Zobrazeno 1 - 10
of 566
pro vyhledávání: '"M. Rajadhyaksha"'
Publikováno v:
EJC Skin Cancer, Vol 2, Iss , Pp 100097- (2024)
Externí odkaz:
https://doaj.org/article/ac04502b170647b0935777c7e0ac3dcf
Publikováno v:
Channels, Vol 17, Iss 1 (2023)
ABSTRACTRecent human genetic studies have linked a variety of genetic variants in the CACNA1C and CACNA1D genes to neuropsychiatric and neurodevelopmental disorders. This is not surprising given the work from multiple laboratories using cell and anim
Externí odkaz:
https://doaj.org/article/8bc61feed9044c26881d1ca1bee22015
Autor:
Robert N. Fetcho, Baila S. Hall, David J. Estrin, Alexander P. Walsh, Peter J. Schuette, Jesse Kaminsky, Ashna Singh, Jacob Roshgodal, Charlotte C. Bavley, Viraj Nadkarni, Susan Antigua, Thu N. Huynh, Logan Grosenick, Camille Carthy, Lauren Komer, Avishek Adhikari, Francis S. Lee, Anjali M. Rajadhyaksha, Conor Liston
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Social hierarchies exert a powerful influence on behavior, but the neurobiological mechanisms that detect and regulate hierarchical interactions are not well understood, especially at the level of neural circuits. Here, we use fiber photomet
Externí odkaz:
https://doaj.org/article/34af93d96a52438193e6be935526d228
Autor:
Melissa C. Knouse, Anna G. McGrath, Andre U. Deutschmann, Matthew T. Rich, Lia J. Zallar, Anjali M. Rajadhyaksha, Lisa A. Briand
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-9 (2022)
Highlights Female mice exhibit heightened synaptosomal expression of AMPAR subunits GluA1 and GluA2 in the mPFC compared to males. Females have enhanced glutamatergic transmission in the mPFC compared to males. There are baseline sex differences in t
Externí odkaz:
https://doaj.org/article/f37542aace1049dfa38fb01f4058297a
Autor:
Hong-Gang Wang, Charlotte C. Bavley, Anfei Li, Rebecca M. Jones, Jonathan Hackett, Yared Bayleyen, Francis S. Lee, Anjali M. Rajadhyaksha, Geoffrey S. Pitt
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
SCN2A, encoding the neuronal voltage-gated Na+ channel NaV1.2, is one of the most commonly affected loci linked to autism spectrum disorders (ASDs). Most ASD-associated mutations in SCN2A are loss-of-function mutations, but studies examining how such
Externí odkaz:
https://doaj.org/article/9a95e5204ad949b9b723b025420aa482
Publikováno v:
Journal of Pharmaceutical Sciences. 112:868-876
Injectable, thermosensitive hydrogels, constructed from cross-linked polymers, can offset the limitations of other sustained release delivery systems, overcome constrains of available therapies, and improve patient compliance to chronic therapy. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9190837b09c803f174855568af0e3a
https://doi.org/10.1016/j.xphs.2022.11.022
https://doi.org/10.1016/j.xphs.2022.11.022
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a strong genetic basis. The role of de novo mutations in ASD has been well established, but the set of genes implicated to date is still far from complete. The current stud
Externí odkaz:
https://doaj.org/article/668731df287a4d50a6197530ad1e1daf
Publikováno v:
Neurobiology of Stress, Vol 7, Iss , Pp 27-37 (2017)
Chronic stress is known to precipitate and exacerbate neuropsychiatric symptoms, and exposure to stress is particularly pathological in individuals with certain genetic predispositions. Recent genome wide association studies have identified single nu
Externí odkaz:
https://doaj.org/article/d7276c54d8694ad99e68cac826ec6894
Autor:
Herie Sun, Anjali M Rajadhyaksha
Publikováno v:
Calcium Signals ISBN: 9780750320092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614b85ad654f64ed2a2a8d13962d9123
https://doi.org/10.1088/978-0-7503-2009-2ch14
https://doi.org/10.1088/978-0-7503-2009-2ch14
Autor:
Melis Inan, Mingrui Zhao, Monica Manuszak, Cansu Karakaya, Anjali M. Rajadhyaksha, Virginia M. Pickel, Theodore H. Schwartz, Peter A. Goldstein, Giovanni Manfredi
Publikováno v:
Neurobiology of Disease, Vol 93, Iss , Pp 35-46 (2016)
Parvalbumin-expressing, fast spiking interneurons have high-energy demands, which make them particularly susceptible to energy impairment. Recent evidence suggests a link between mitochondrial dysfunction in fast spiking cortical interneurons and neu
Externí odkaz:
https://doaj.org/article/0fc74e59f61f42da95e50166e4648e1d