Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M. R. Zalutsky"'
Autor:
M R, Zalutsky, O R, Pozzi
Publikováno v:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 48(4)
An important consideration in the development of effective strategies for radioimmunotherapy is the nature of the radiation emitted by the radionuclide. Radionuclides decaying by the emission of alpha-particles offer the possibility of matching the c
Autor:
M. R. Zalutsky
The overall objective of this project was to investigate the use of local hyperthermia as a means for improving the potential utility of radiolabeled monoclonal antibodies for tumor therapy. Hyperthermia not only can alter tumor hemodynamics but also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590d5133420a7ee76f813026f8e694e1
https://doi.org/10.2172/825909
https://doi.org/10.2172/825909
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(10)
In vitro and in vivo studies in human glioma models suggest that the antitenascin monoclonal antibody 81C6 labeled with the 7.2-h-half-life alpha-particle emitter (211)At might be a valuable endoradiotherapeutic agent for the treatment of brain tumor
Autor:
I, Cokgor, G, Akabani, H S, Friedman, A H, Friedman, M R, Zalutsky, L M, Zehngebot, J M, Provenzale, C D, Guy, C J, Wikstrand, D D, Bigner
Publikováno v:
Cancer. 91(9)
Even with novel chemotherapeutic agents and external beam radiation therapy, the prognosis of neoplastic meningitis secondary to malignant melanoma is still dismal. The authors report a case study of a 46-year-old white female who presented with prog
Publikováno v:
Cancer research. 61(4)
Elastin-like polypeptides (ELPs) are biopolymers of the pentapeptide repeat Val-Pro-Gly-Xaa-Gly that undergo an inverse temperature phase transition. They are soluble in aqueous solutions below their transition temperature (T1) but hydrophobically co
Publikováno v:
International journal of cancer. 88(6)
Combinatorial variation of CDR3 of V(H) and V(L), followed by phage display, was used to select affinity mutants of the parental anti-epidermal growth factor receptor-vIII (EGFRvIII) scFv MR1. One mutant, MR1-1(scFv), had increased specific binding a
Publikováno v:
Cancer research. 60(16)
The mutant epidermal growth factor receptor variant III (EGFRvIII) has been found on gliomas and other tumors but not on normal tissues, including those that express the wild-type receptor. Monoclonal antibodies (mAbs) specific for EGFRvIII are rapid
Autor:
F, Xu, S A, Leadon, Y, Yu, C M, Boyer, K, O'Briant, K, Ward, A, McWatters, X, Zhao, D S, Bae, K, DeSombre, M R, Zalutsky, R C, Bast
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
Radionuclide conjugates or ricin A chain (RTA) immunotoxins that target pl85HER-2 have partially inhibited the growth of human ovarian cancer xenografts in athymic mice but generally have not cured mice bearing human tumor transplants. The present st
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(7)
Bisphosphonates were synthesized for use as carriers for astatine and iodine radioisotopes to target bone neoplasms.Radiohalogenated activated esters were coupled to the amino group in the side chain of the bisphosphonate. The bisphosphonate 3-amino-