Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M. R. Szewczak"'
Autor:
Hugo M. Vargas, J. T. Strupczewski, L. Griffiths, R. Corbett, J. E. Shipley, S. Kongsamut, A. M. Szczepanik, U. Shukla, D. J. Turk, M. R. Szewczak
Publikováno v:
CNS Drug Reviews. 3:120-147
Schizophrenia is a severe mental illness affecting an estimated 1% of the world's population (73). The disease has an uncertain pathophysiology possibly leading to disruption of dopaminergic neural systems through poorly understood interactions of an
Autor:
Lawrence L. Martin, Douglas K. Rush, J. E. Roehr, J. T. Klein, Francis P. Huger, M. R. Szewczak, R. Corbett, A. Giovanni, Richard C. Effland, R. D. Porsolt, A. T. Woods-Kettelberger, C. P. Smith, D. J. Turk, E. M. DiLeo, G. M. Bores, S. Kongsamut
Publikováno v:
CNS Drug Reviews. 3:1-23
Autor:
A. T. Woods-Kettelberger, R. Corbett, S. Kongsamut, J. T. Klein, M. R. Szewczak, G. M. Bores, C. P. Smith, J. E. Roehr
Publikováno v:
Brain Research Bulletin. 41:125-130
The aim of the present paper is to report on the adrenergic and serotonergic effects of besipirdine (HP 749) in vivo and to discuss its potential use in the treatment of obsessive compulsive disorder. Besipirdine inhibited biogenic amine uptake in vi
Autor:
A T, Woods-Kettelberger, C P, Smith, R, Corbett, M R, Szewczak, J E, Roehr, G M, Bores, J T, Klein, S, Kongsamut
Publikováno v:
Brain research bulletin. 41(2)
The aim of the present paper is to report on the adrenergic and serotonergic effects of besipirdine (HP 749) in vivo and to discuss its potential use in the treatment of obsessive compulsive disorder. Besipirdine inhibited biogenic amine uptake in vi
Autor:
M R, Szewczak, R, Corbett, D K, Rush, C A, Wilmot, P G, Conway, J T, Strupczewski, M, Cornfeldt
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(3)
Iloperidone (1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone) demonstrated a potent antipsychotic profile in several in vitro and in vivo animal models. Iloperidone displaced ligand binding at D2 dopamine
Autor:
S, Fielding, M R, Szewczak
Publikováno v:
The Journal of clinical psychiatry. 45(4 Pt 2)
Nomifensine has demonstrated efficacy in several animal models that have been found to be predictive of clinical antidepressant activity, and has also been found to have a low potential for both cardiovascular and anticholinergic side effects. A comp