Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. R. Shurin"'
Publikováno v:
Russian Journal of Biotherapy. 16:12-23
Dendritic cells play key role during tumorigenesis and immune response to it. They are able to uptake and present antigens to T cells, resulting in specific T cell mediated immune response. Furthermore, interaction between dendritic cells and other t
Publikováno v:
Russian Journal of Biotherapy. 15:25-33
Immune system plays a crucial role in tumor growth process. It exerts cancer surveillance function via innate and adaptive immune mechanisms, nonetheless tumor may exploit various immune cells to escape specific immune response. Dendritic cells are t
Autor:
Gennady T. Sukhikh, M. S. Solov'eva, M. R. Shurin, V. V. Mit'kin, G. B. Kirillicheva, S. F. Pshenichkin, A. A. Zozulya
Publikováno v:
Bulletin of Experimental Biology and Medicine. 114:1475-1478
Publikováno v:
Histology and histopathology. 20(4)
A number of antibodies that recognize human dendritic cells (DC) have been identified. The main aim of this study was to compare and contrast different antigen retrieval techniques using both enzymatic and non-enzymatic treatments in order to determi
Autor:
C, Esche, G V, Shurin, J M, Kirkwood, G Q, Wang, H, Rabinowich, G, Pirtskhalaishvili, M R, Shurin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7
Melanoma escapes host defenses through a variety of means, including the elimination of immune effector cells within the tumor microenvironment. We have reported recently that murine and human tumors including melanoma induce premature apoptosis of d
Publikováno v:
Current opinion in molecular therapeutics. 1(1)
Dendritic cells (DC) are the most potent antigen presenting cells (APC) and the only ones capable of presenting novel antigens to naïve T-cells. Large numbers of DC can be generated in vitro in the presence of appropriate cytokine cocktails using ei
Publikováno v:
Cancer research. 61(1)
Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common extracranial solid tumor in children. NB-derived gangliosides inhibit the functional activity of T and natural killer cells, contribute to tumor-induced bone marrow sup
Publikováno v:
European journal of immunology. 30(9)
Interleukin-12 (IL-12) and Flt3 ligand (FL) regulate hematopoiesis by stimulating proliferation, differentiation and migration of progenitor and/or stem cells. In this study, we evaluated the in vivo effect of IL-12 alone or in combination with FL on
Publikováno v:
Forum (Genoa, Italy). 10(3)
Incidence and mortality of human malignant melanoma has risen rapidly over recent decades. Systemic therapies for metastatic cutaneous melanoma, the most aggressive of all skin cancers, remain disappointing although immunological treatment has been m
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(6)
The cytokine FLT3 ligand (FL) enhances dendritic cell (DC) generation and has therefore been proposed as a means to boost antitumor immunity. Vascular endothelial growth factor (VEGF) is produced by a large percentage of tumors and is required for de