Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M. R. Pickard"'
Autor:
John Pablo Valladares, Angel E. Spotorno, John M. McArthur, Arnaldo Vilaxa, AK Sinha, Annette Duerr, Bastien D. Gomperts, Gertrudis Cabello, Richard Sullivan, M. R. Pickard, Isabel Behncke
Publikováno v:
Scopus-Elsevier
Lack of dietary iodine is associated with thyroid insufficiency and its dire consequences including cretinism, yet territories severely deficient in iodine are home to many species of wild animals. The premise of our work is that an adaptation must b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4320d1738c4617bbfa8b311c4582734
https://doi.org/10.1007/s00424-002-0972-0
https://doi.org/10.1007/s00424-002-0972-0
Publikováno v:
Journal of Endocrinology. 176:247-255
Maternal hypothyroidism impairs fetal growth in the rat, but the mechanisms by which this occurs are unknown. Since the fetus derives its glucose supply from the mother, and maternal thyroidectomy may disturb maternal and placental glucose metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6c8cb17e31b2acaa72b5f58e9aff6d
https://doi.org/10.1677/joe.0.1760247
https://doi.org/10.1677/joe.0.1760247
Publikováno v:
Journal of Endocrinology. 175:597-604
Maternal hypothyroidism during pregnancy impairs brain function in human and rat offspring, but little is known regarding the influence of maternal hyperthyroidism on neurodevelopment. We have previously shown that the expression of neuronal and glia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8527812b87069c07c5dcc6b0a364e828
https://doi.org/10.1677/joe.0.1750597
https://doi.org/10.1677/joe.0.1750597
Publikováno v:
Journal of Endocrinology. 167:439-445
Maternal thyroid hormone (TH) crosses the placenta and is postulated to regulate fetal brain development. However, TH-dependent stages of fetal brain development remain to be characterised. We have therefore compared the levels of several neuronal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41723a9adb6d043e4b80c4510f972055
https://doi.org/10.1677/joe.0.1670439
https://doi.org/10.1677/joe.0.1670439
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:2620-2623
Maternal thyroid hormone is transferred to the fetus early in pregnancy and is postulated to regulate brain development. Thyroid hormone nuclear receptor (TR) proteins are present in fetal brain, but their isoformal composition is unknown. We therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2508b7d44172716c882db2e8ed9d07
https://doi.org/10.1210/jcem.85.7.6766
https://doi.org/10.1210/jcem.85.7.6766
Publikováno v:
ChemInform. 44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b3c1d30ecc9f65168bd4872ae6f980
https://doi.org/10.1002/chin.201346122
https://doi.org/10.1002/chin.201346122
Publikováno v:
Organicbiomolecular chemistry. 11(29)
3-(4-Chlorophenyl)-4-substituted pyrazole derivatives were synthesised and tested for their in vitro antifungal activity. Some compounds showed very good antifungal activity against four pathogenic strains of fungi. The same compounds exhibited an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217194ac41d84da5bb823d444c276fbe
https://pubmed.ncbi.nlm.nih.gov/23779132
https://pubmed.ncbi.nlm.nih.gov/23779132
Publikováno v:
Journal of Endocrinology. 139:205-212
The influence of maternal hypothyroxinaemia on early brain and placental development was examined in a partially thyroidectomized (parathyroid-spared; TX) rat dam model. Ornithine decarboxylase (ODC) specific activity, along with more general indices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a987fb8668e02b8e08bff3c0594bbbae
https://doi.org/10.1677/joe.0.1390205
https://doi.org/10.1677/joe.0.1390205
Publikováno v:
Journal of Endocrinology. 138:299-305
The influence of hypothyroidism in the adult rat on brain biochemistry was investigated. Hypothyroidism was induced in 6-month-old male rats by partial thyroidectomy coupled with the administration of 6-n-propyl-2-thiouracil (0·005%, w/v) in the dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3221252cb62569b6121ac53347349b63
https://doi.org/10.1677/joe.0.1380299
https://doi.org/10.1677/joe.0.1380299
Publikováno v:
Journal of Endocrinology. 124:387-396
The effects of maternal hypothyroxinaemia during pregnancy on subsequent brain biochemistry in progeny was studied. Normal and partially thyroidectomized rat dams were mated and progeny allowed to grow to adulthood. Brain regions (cerebellum, medulla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d91c479fc233e8015de836e185d171
https://doi.org/10.1677/joe.0.1240387
https://doi.org/10.1677/joe.0.1240387