Zobrazeno 1 - 10
of 20
pro vyhledávání: '"M. R. MacLean"'
Publikováno v:
Textbook of Vascular Medicine ISBN: 9783030164805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf4a3d6fb26a9c17f5a4e2cf6953466
https://doi.org/10.1007/978-3-030-16481-2_41
https://doi.org/10.1007/978-3-030-16481-2_41
Autor:
M. R. Maclean, Kathleen A. Kane, Roger M. Wadsworth, K.M. McCulloch, V. S. N. M. R. Karamsetty
Publikováno v:
Respiration Physiology. 105:85-93
The aim of this study was to characterise the response to acute hypoxia in pulmonary artery rings isolated from rats exposed to chronic hypoxia for 2 weeks (CH) and following recovery in room air for 24 h (post hypoxic, PH). Large intrapulmonary arte
Autor:
Kirsty M. McCulloch, M. R. MacLean
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:S169-176
Publikováno v:
Endothelium. 1:251-258
The effects of hypoxia on endothelin-1 (ET-1) release were studied in vitro in human, sheep (under resting force) and preconstricted rabbit pulmonary artery rings. Hypoxic contraction in human and sheep arteries was well maintained, while that in rab
Autor:
M. R. Maclean
Publikováno v:
Azania: Archaeological Research in Africa. :296-302
A partir des resultats d'une prospection archeologique du district de Rakai (Lac Victoria, sud-ouest de l'Ouganda) et des donnees ethnographiques, l'auteur examine les consequences de l'evolution de l'environnement et le passage de la technologie de
Publikováno v:
Handbook of experimental pharmacology. (204)
Pulmonary arterial hypertension (PAH) is characterized by increased mean pulmonary artery pressure (mPAP) due to vasoconstriction and structural changes in the small pulmonary arteries (PAs); proliferation of pulmonary artery smooth muscle cells (PAS
Autor:
N F, Kelland, A J, Bagnall, I, Morecroft, F H, Gulliver-Sloan, Y, Dempsie, M, Nilsen, M, Yanagisawa, M R, Maclean, Y V, Kotelevtsev, D J, Webb
Publikováno v:
Journal of vascular research. 47(1)
We hypothesised that the potential protective effects of endothelial ET(B) are important in limiting pulmonary vascular muscularisation, vasoconstriction and the development of pulmonary arterial hypertension in response to hypoxia.EC-specific ET(B)
Publikováno v:
British journal of pharmacology. 155(4)
While the 5-HT and Rho-kinase (ROCK) pathways have been implicated in the development of pulmonary arterial hypertension (PAH), the nature of any interactions between them remain unclear. This study investigated a role for ROCK in 5-HT-regulated prol
Autor:
M R, MacLean
Publikováno v:
International journal of clinical practice. Supplement. (156)
In the 1960s, serotonin (5HT) was associated with pulmonary arterial hypertension (PAH) caused by certain diet pills, but has recently been the subject of renewed interest in the field of PAH. Serotonin can be synthesised in the pulmonary endothelium
Publikováno v:
Circulation research. 89(12)
5-Hydroxytryptamine (5-HT)(1B) receptors mediate contraction in human pulmonary arteries, and 5-HT(1B) receptor-mediated contraction is enhanced in pulmonary arteries from hypoxic rats. Here we further examine the role of this receptor in the develop