Zobrazeno 1 - 10
of 44
pro vyhledávání: '"M. R. Lerner"'
Publikováno v:
Biochemical pharmacology. 62(9)
We sought to clone and characterize the murine cysteinyl-leukotriene D(4) receptor (mCysLT(1)R) to complement our studies with leukotriene-deficient mice. A cDNA, cloned from trachea mRNA by reverse transcriptase-polymerase chain reaction, has two po
Publikováno v:
Pigment cell research. 14(4)
Xenopus laevis dermal melanophores provide an excellent model system for the investigation of complex cellular processes. Specifically, the expression of exogenous genes in Xenopus melanophores is the basis of recombinant bioassays for the study of r
Autor:
C. K. Jayawickreme, M. R. Lerner
Publikováno v:
The Pharmacology of Functional, Biochemical, and Recombinant Receptor Systems ISBN: 9783642630286
This chapter describes the development and application of a Xenopus laevis melanophore recombinant system to study receptor-ligand interactions. Many Poikilothermie vertebrates possess the ability to change their skin color rapidly. The cells respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc827869fb1fd578208c2cd212b7d21
https://doi.org/10.1007/978-3-642-57081-0_16
https://doi.org/10.1007/978-3-642-57081-0_16
Publikováno v:
Journal of Biological Chemistry. 266:11234-11236
Blood feeding by the sand fly Lutzomyia longipalpis is aided by the presence of a vasodilator in its salivary glands. This novel vasodilator has been isolated by reversed-phase high-performance liquid chromatography. Ten nanograms of the vasodilator
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
The goal of the present study was to investigate a possible role for regulators of G protein-signaling (RGS) proteins in opioid receptor (OR) desensitization using cultured Xenopus laevis dermal melanophores. Morphine-induced pigment aggregation in a
Autor:
J S, Hanas, M R, Lerner, S A, Lightfoot, C, Raczkowski, D J, Kastens, D J, Brackett, R G, Postier
Publikováno v:
Cancer. 86(5)
Barrett esophagus predisposes individuals to esophageal carcinoma, which develops from intermediate stages of tissue dysplasia primarily in the vicinity of the gastroesophageal junction. Understanding the cellular and molecular events in the progress
Publikováno v:
Photodermatology, photoimmunologyphotomedicine. 15(1)
Publikováno v:
The Journal of the Oklahoma State Medical Association. 91(7)
Blast wave injury from bombs cause a unique but poorly understood spectrum of injuries. Previous blast wave models involved high energy explosives detonated in an open field without the sophisticated monitoring of laboratory equipment. We characteriz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 78
Autor:
J D, Alvaro, J B, Tatro, J M, Quillan, M, Fogliano, M, Eisenhard, M R, Lerner, E J, Nestler, R S, Duman
Publikováno v:
Molecular pharmacology. 50(3)
Melanocortin peptides are reported to antagonize opiate dependence and tolerance, but the neural substrates underlying these actions are unknown. In this study, we characterize the rat melanocortin-4 receptor (MC4-R) and demonstrate that this recepto