Zobrazeno 1 - 10
of 41
pro vyhledávání: '"M. R. Lakshman"'
Autor:
M. R. Lakshman
Publikováno v:
The Journal of Nutrition. 134:241S-245S
In early 1900s, based on indirect evidence, Steenbock and Morton independently predicted that beta-carotene could be the biological precursor of vitamin A, although this notion was contested by others. In the 1930s, Thomas Moore showed the in vivo fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774e99a36b7b0c187a60fb86e88373d8
https://doi.org/10.1093/jn/134.1.241s
https://doi.org/10.1093/jn/134.1.241s
Autor:
Qing-Hong Liu, Doris B Strader, M. R. Lakshman, Leonard B. Seeff, Philippe Marmillot, Manjunath N. Rao
Publikováno v:
Metabolism. 49:1406-1410
We have previously shown that chronic alcohol consumption leads to inhibition of sialylation of apolipoprotein E (apo E) that results in its impaired binding to high-density lipoprotein (HDL) molecule. Because apo E plays a major role in reverse chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e97a6087b50b102b6283c317657da49
https://doi.org/10.1053/meta.2000.17728
https://doi.org/10.1053/meta.2000.17728
Publikováno v:
The American Journal of Clinical Nutrition. 72:190-198
Background: Plasma apolipoprotein (apo) E, a sialoprotein, plays an important role in reverse cholesterol transport. Previously, we showed that chronic alcohol consumption impairs glycosylation of apo E in rat liver. Peritoneal macrophages are anothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34a0e2d1ab15e40e8dfe8ee5e90dd2d
https://doi.org/10.1093/ajcn/72.1.190
https://doi.org/10.1093/ajcn/72.1.190
Publikováno v:
Alcohol. 19:239-247
Chronic alcohol exposure leads to the appearance of carbohydrate-deficient transferrin (CDT), a N- glycosylated protein and sialic acid-deficient apolipoprotein E (apoE), an O -glycosylated protein. We show that chronic ethanol treatment destabilizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fe920c4e53454f76bee744f5abfa4b
https://doi.org/10.1016/s0741-8329(99)00041-5
https://doi.org/10.1016/s0741-8329(99)00041-5
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:376-380
In view of the chronic alcohol-mediated pathological changes in various sialic acid-deficient glycoconjugates and the potential importance of sialidase in the generation of these glycoconjugates in the blood compartment and in the brain, we have inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3fc321594577711321febd5924c5a7
https://doi.org/10.1111/j.1530-0277.1999.tb04125.x
https://doi.org/10.1111/j.1530-0277.1999.tb04125.x
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 10, Pp 1545-1550 (1989)
Absorption and storage of [14C]beta-carotene in control and beta-carotene-fed (BC-fed) rats were determined. Pre-feeding with beta-carotene for 2 weeks caused a 1.9-fold stimulation of its own absorption as well as its conversion to retinyl esters, w
Externí odkaz:
https://doaj.org/article/1539c65211d74aadb660dfef3000b547
Publikováno v:
Hepatology. 25:1451-1456
Various lipid parameters were determined in lean control and LA/NIH-corpulent (LA/N-cp) rats, a normotensive strain showing metabolic characteristics associated with human Type IV hyperlipidemia. Hepatic and plasma total cholesterol, high density lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30746f1bbac1b7335459f6ff80ae69f
https://doi.org/10.1002/hep.510250624
https://doi.org/10.1002/hep.510250624
Autor:
M. R. Lakshman, Manjunath N. Rao
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:348-351
We have previously demonstrated that chronic ethanol specifically decreases the hepatic level and rate of synthesis of 2,6-sialyltrans-ferase (2,6-ST). To understand its mechanism of action, effects of 8 weeks of chronic ethanol feeding on the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1903726474d35fcba3125e3e6cb42e45
https://doi.org/10.1111/j.1530-0277.1997.tb03771.x
https://doi.org/10.1111/j.1530-0277.1997.tb03771.x
Autor:
Pradeep Ghosh, M. R. Lakshman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:76-81
In recent years, a number of studies have been reported that have clearly established that hepatic glycosylation machinery is affected by chronic ethanol treatment in rats. We have previously reported that chronic ethanol treatment in rats resulted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd63a7d76748b2e46fba90395e2703d
https://doi.org/10.1111/j.1530-0277.1997.tb03731.x
https://doi.org/10.1111/j.1530-0277.1997.tb03731.x
Publikováno v:
Nutrition and Cancer. 26:49-61
Dietary beta-carotene has been shown to have cancer chemopreventive action on the basis of epidemiologic evidence and studies in animals. Because the anticarcinogenic property of beta-carotene may be exerted per se, it is desirable to achieve the max
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f4bb7340ef41bd750479f5114d5ed5
https://doi.org/10.1080/01635589609514462
https://doi.org/10.1080/01635589609514462