Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M. R. L. Stratford"'
Autor:
Y. Y. Zheng, P. J. Dobson, Ahmed Ashour Ahmed, Yiyan Zheng, Helen E. Townley, M. R. L. Stratford, Juliet Goldsmith
Publikováno v:
Nanoscale. 7:1127-1135
This study describes a system for quantifying paclitaxel activity using the C-terminus of α-tubulin as a biomarker. Following stabilization of microtubules with paclitaxel, a specific detyrosination reaction occurs at the C-terminus of α-tubulin wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31975fb05386cc6a9f5da3b8cfc5d652
https://doi.org/10.1039/c4nr01105h
https://doi.org/10.1039/c4nr01105h
Publikováno v:
British Journal of Cancer
Large fluctuations in glutathione content were observed on a daily basis using the Tietze enzyme recycling assay in a panel of six human cell lines of varying radiosensitivity. Glutathione content tended to increase to a maximum during exponential ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c8e9601670afaf816241bf75378bf6
http://europepmc.org/articles/PMC2033930
http://europepmc.org/articles/PMC2033930
Autor:
Madeleine F. Dennis, R. R. Watfa, G. J. S. Rustin, M. R. L. Stratford, N. Howells, S. M. O'reilly
Publikováno v:
British Journal of Cancer
Flavone acetic acid (FAA) was administered at a dose of 4.8 g m-2 over 1 h to patients with advanced malignant disease in combination with Interleukin II. A new high performance liquid chromatography method is described to determine both the parent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc1219e9ea19fbdaab5abd4a037ae0
https://doi.org/10.1038/bjc.1993.250
https://doi.org/10.1038/bjc.1993.250
Publikováno v:
British Journal of Cancer
The role of nitric oxide (NO) in the response to Photofrin-based photodynamic therapy (PDT) was investigated using mouse tumour models characterized by either relatively high or low endogenous NO production (RIF and SCCVII vs EMT6 and FsaR, respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b42bf617754b6250057e966d584a42
http://ora.ox.ac.uk/objects/uuid:e3ad219b-015a-4e4d-91b0-4f1cb255d30b
http://ora.ox.ac.uk/objects/uuid:e3ad219b-015a-4e4d-91b0-4f1cb255d30b
Publikováno v:
The Journal of pathology. 139(2)
The toxicity to cultured cells of the cancer chemotherapeutic agent methylglyoxal-bis[guanylhydrazone] (MGBG) varies considerably between different cell lines and is always more toxic in the absence of exogenous polyamine. We have looked at the relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c76eb671dea02ca5451d3a08cb0fa1
https://pubmed.ncbi.nlm.nih.gov/6827399
https://pubmed.ncbi.nlm.nih.gov/6827399
Autor:
R. J. Hodgkiss, M. R. L. Stratford
Publikováno v:
The British Journal of Radiology. 59:83-84
The role of glutathione in radioprotection has been much investigated, but relatively little attention has been paid to ascorbate, which is present at high concentrations in human tumours (Kakar & Wilson, 1974; Moriarty et al, 1977). Both glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f1fe4de8d97ce2a2fcbe2ba1c66248
https://doi.org/10.1259/0007-1285-59-697-83
https://doi.org/10.1259/0007-1285-59-697-83