Zobrazeno 1 - 10 of 21 pro vyhledávání: '"M. R. Hadam"'
1
A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)
Autor: Walter Reith, M. R. Hadam, Bénédicte Durand, Bernard Mach, Madeleine Zufferey, Emmanuèle Barras, Viktor Steimle
Publikováno v: Genes and Development, Vol. 9, No 9 (1995) pp. 1021-1032
Regulation of MHC class II gene expression is an essential aspect of the control of the immune response. Primary MHC class II deficiency is a genetically heterogeneous disease of gene regulation that offers the unique opportunity of a genetic approac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df20c5035927947188b8e9f9b7b0cb42
https://doi.org/10.1101/gad.9.9.1021
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2
Production of interleukin-1 beta and interleukin-6 in hepatoblastoma
Autor: D von Schweinitz, Torsten Pietsch, Karl Welte, M R Hadam, H. Mildenberger
Publikováno v: International journal of cancer. 53(5)
Thrombocytosis and fever are frequent symptoms in children with hepatoblastoma. Interleukin-6 (IL-6) has been shown to mediate thrombocytosis and an acute-phase reaction including fever. We therefore investigated samples from 14 untreated patients wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c66ee09074c37384d78c32d692e934e
https://pubmed.ncbi.nlm.nih.gov/8383628
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3
Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: heterogeneity in response and synergy with other hematopoietic growth factors
Autor: T, Pietsch, U, Kyas, U, Steffens, E, Yakisan, M R, Hadam, W D, Ludwig, K, Zsebo, K, Welte
Publikováno v: Blood. 80(5)
A novel hematopoietic growth factor, the stem cell factor (SCF), for primitive hematopoietic progenitor cells has recently been purified and its gene has been cloned. In this study we tested the mitogenic activity of recombinant human SCF on myeloid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e78948bbe0a20b06bf6611808ab68ab
https://pubmed.ncbi.nlm.nih.gov/1381238
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4
Mitotic disturbance associated with mosaic aneuploidies
Autor: L. Winkler, W. Müller, J. H. H. Ehrich, M. R. Hadam, Sibylle D. Flatz, K. Miller
Publikováno v: Human genetics. 84(4)
The association of various unsystematic aneuploidies with premature centromere division (PCD) was observed in a patient with conspicuous clinical features and combined immunodeficiency. Trisomies and monosomies of almost all autosomes and gonosomal a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb450ed242efc7d732a40d5b1565dbc
https://pubmed.ncbi.nlm.nih.gov/2307459
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5
Lymphocyte subsets in Crohn’s disease
Autor: M. R. Hadam, M. Burdelski, B. Rodeck
Publikováno v: Inflammatory Bowel Disease and Coeliac Disease in Children ISBN: 9789401073240
The aetiology of Crohn’s disease remains unresolved, though it is generally accepted that the immune system may be involved in its pathogenesis. Peripheral blood lymphocytes have been the starting point for many investigations of immune function, m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e169b82ddb44a13d132d90deeb0d859a
https://doi.org/10.1007/978-94-009-1850-4_6
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8
Inherited Immunodeficiency with a Defect in a Major Histocompatibility Complex Class II Promoter-Binding Protein Differs in the Chromatin Structure of the HLA-DRA Gene
Autor: C. Griscelli, B. Lisowska-Grospierre, Emmanuèle Barras, M. R. Hadam, Walter Reith, Bernard Mach, Pierre Gönczy
Publikováno v: Molecular and Cellular Biology, Vol. 9, No 1 (1989) pp. 296-302
A defect in a trans-regulatory factor which controls major histocompatibility complex class II gene expression is responsible for an inherited form of immunodeficiency with a lack of expression of human leukocyte antigen (HLA) class II antigens. We h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d12d26033d70b2d94aef2ad5144751
https://doi.org/10.1128/mcb.9.1.296-302.1989
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9
Divergent Expression of HLA-DC/MB, -DR, and -SB region products on normal and pathological tissues as detected by monoclonal antibodies
Autor: Claudia A. Müller, G. A. Müller, Andreas Ziegler, H. D. Waller, C. A. Müller, M. R. Hadam, P. Kernet
Publikováno v: Immunobiology. 169:228-249
A group of eight monoclonal antibodies directed against different monomorphic determinantsof HLA-class II molecules was used to investigate the distribution of HLA-DC/DS/MB, -DR and -SB-like antigens on normal and pathological lymphoid and nonlymphoi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa5b8001d4001cf7138f904a873310b
https://doi.org/10.1016/s0171-2985(85)80036-x
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10
Regulation of Genes for HLA Class II Antigens in Cell Lines from Patients with Severe Combined Immunodeficiency
Autor: M. R. Hadam, Bernard Mach, C. de Préval
Publikováno v: New England Journal of Medicine. 318:1295-1300
HLA Class II-negative severe combined immunodeficiency (SCID) results from a congenital defect characterized by an absence of HLA Class II antigens. Patients with the disorder have no HLA-DR, DQ, or DP antigens or mRNAs in their peripheral-blood lymp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a359685ebb8179acc8ebfe7c77f317
https://doi.org/10.1056/nejm198805193182003
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