Zobrazeno 1 - 10
of 681
pro vyhledávání: '"M. Quiros"'
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Mechanical ventilation is often employed to facilitate breathing in patients suffering from respiratory illnesses and disabilities. Despite the benefits, there are risks associated with ventilator-induced lung injuries and death,
Externí odkaz:
https://doaj.org/article/b6316024989449bd8dea18d04b197cbe
Autor:
Talyah M. Nelson, Kathrine A. M. Quiros, Crystal A. Mariano, Samaneh Sattari, Arzu Ulu, Edward C. Dominguez, Tara M. Nordgren, Mona Eskandari
Publikováno v:
Physiological Reports, Vol 10, Iss 19, Pp n/a-n/a (2022)
Abstract Pulmonary diseases alter lung mechanical properties, can cause loss of function, and necessitate use of mechanical ventilation, which can be detrimental. Investigations of lung tissue (local) scale mechanical properties are sparse compared t
Externí odkaz:
https://doaj.org/article/f8da7d78645443af8ea07c8e4ea45cd2
Autor:
Silvia Basilico, Xiaonan Wang, Alison Kennedy, Konstantinos Tzelepis, George Giotopoulos, Sarah J. Kinston, Pedro M. Quiros, Kim Wong, David J. Adams, Larissa S. Carnevalli, Brian J. P. Huntly, George S. Vassiliou, Fernando J. Calero-Nieto, Berthold Göttgens
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The oncogene MLL is frequently translocated in leukemia, resulting in oncogenic fusion proteins. Here, the authors report a temporally controlled mouse model of MLL-ENL driven leukemia AND identify therapeutic targets associated with early MLL-ENL dr
Externí odkaz:
https://doaj.org/article/f3f11e1f04f14988aa6abc97b3c99275
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/452d846ba04347e98a432bfe4b77576d
Autor:
Olli Matilainen, Maroun S. Bou Sleiman, Pedro M. Quiros, Susana M. D. A. Garcia, Johan Auwerx
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Changes in chromatin structure have been linked to organismal ageing. Here the authors show that altered histone expression and mitochondrial stress during C. elegans development result in chromatin changes and a cytosolic stress response that affect
Externí odkaz:
https://doaj.org/article/f2448e82fe1a47ca8ebd24b4a5a05de3
Akademický článek
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Akademický článek
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Publikováno v:
Scientific reports, vol 13, iss 1
Tissue remodeling in pulmonary disease irreversibly alters lung functionality and impacts quality of life. Mechanical ventilation is amongst the few pulmonary interventions to aid respiration, but can be harmful or fatal, inducing excessive regional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794874de96a9a918c3067381ac74d5d2
https://escholarship.org/uc/item/6n23g61x
https://escholarship.org/uc/item/6n23g61x
Autor:
Norman Moullan, Laurent Mouchiroud, Xu Wang, Dongryeol Ryu, Evan G. Williams, Adrienne Mottis, Virginija Jovaisaite, Michael V. Frochaux, Pedro M. Quiros, Bart Deplancke, Riekelt H. Houtkooper, Johan Auwerx
Publikováno v:
Cell Reports, Vol 10, Iss 10, Pp 1681-1691 (2015)
In recent years, tetracyclines, such as doxycycline, have become broadly used to control gene expression by virtue of the Tet-on/Tet-off systems. However, the wide range of direct effects of tetracycline use has not been fully appreciated. We show he
Externí odkaz:
https://doaj.org/article/0dcb4c23bfc94665a9e7844015682049
Autor:
Yifan Zhou, Ruba Shalhoub, Stephanie N. Rogers, Shiqin Yu, Muxin Gu, Margarete A. Fabre, Pedro M. Quiros, Tae-Hoon Shin, Arch Diangson, Wenhan Deng, Shubha Anand, Wenhua Lu, Matthew Cullen, Anna L. Godfrey, Jacobus Preller, Jerome Hadjadj, Emmanuelle Jouanguy, Aurélie Cobat, Laurent Abel, Frederic Rieux-Laucat, Benjamin Terrier, Alain Fischer, Lara Novik, Ingelise J. Gordon, Larisa Strom, Martin R. Gaudinski, Andrea Lisco, Irini Sereti, Thomas J. Gniadek, Andrea Biondi, Paolo Bonfanti, Luisa Imberti, Clifton L. Dalgard, Yu Zhang, Kerry Dobbs, Helen C. Su, Luigi D. Notarangelo, Colin O. Wu, Peter J.M. Openshaw, Malcolm G. Semple, Ziad Mallat, Kenneth Baillie, Cynthia E. Dunbar, George S. Vassiliou
Publikováno v:
Zhou, Y, Shalhoub, R N, Rogers, S N, Yu, S, Gu, M, Fabre, M A, Quiros, P M, Diangson, A, Deng, W, Anand, S, Lu, W, Cullen, M, Godfrey, A L, Preller, J, Hadjadj, J, Jouanguy, E, Cobat, A, Abel, L, Rieux-Laucat, F, Terrier, B, Fischer, A, Novik, L, Gordon, I J, Strom, L, Gaudinski, M, Lisco, A, Sereti, I, Gniadek, T J, Biondi, A, Bonfanti, P, Imberti, L, Zhang, Y, Dalgard, C L, Dobbs, K, Su, H C, Notarangelo, L D, Wu, C O, Openshaw, P J M, Semple, M G, Mallat, Z, Baillie, K, Dunbar, C E & Vassiliou, G S 2022, ' Clonal Hematopoiesis Is Not Significantly Associated with Covid-19 Disease Severity ', Blood, vol. 140, no. 14, pp. 1650-1655 . https://doi.org/10.1182/blood.2022015721
Clonal hematopoiesis (CH) describes the disproportionate expansion of a hematopoietic stemcell (HSC) and its progeny, in association with leukemia-associated somatic mutations, mostcommonly affecting the genes for epigenetic regulators DNMT3A, TET2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b76ab2376652b898353a85bd024178
https://www.repository.cam.ac.uk/handle/1810/340199
https://www.repository.cam.ac.uk/handle/1810/340199