Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M. Quadir Siddiqui"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35158- (2024)
Glucose-6-Phosphate Dehydrogenase (G6PD) is a crucial enzyme that executes the pentose phosphate pathway. Due to its critical nodal position in the metabolic network, it is associated with different forms of cancer tumorigeneses and progression. None
Externí odkaz:
https://doaj.org/article/da0b645fe28e4ad3836cf6b5c9410475
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2647 (2021)
Members of the human Zyxin family are LIM domain-containing proteins that perform critical cellular functions and are indispensable for cellular integrity. Despite their importance, not much is known about their structure, functions, interactions and
Externí odkaz:
https://doaj.org/article/ed98be949f574ff090a5254145d52fc1
Publikováno v:
Biochemical Society Transactions. 50:1415-1426
The long non-coding RNAs (lncRNAs) other than rRNA and tRNA were earlier assumed to be ‘junk genomic material’. However, recent advancements in genomics methods have highlighted their roles not only in housekeeping but also in the progression of
Autor:
Higor Sette Pereira, Darren L. Gemmill, M. Quadir Siddiqui, Gunjan Vasudeva, Trushar R. Patel
Publikováno v:
Journal of Medical Virology. 95
Publikováno v:
International journal of biological macromolecules. 223
RING-B box-coiled coil (RBCC) domain of promyelocytic leukemia (PML) comprises a zinc finger motif that is targeted by arsenic trioxide (ATO) to treat acute promyelocytic leukemia (APL) pathogenesis. Preliminary evidence suggests that the PML-RBCC ha
Publikováno v:
European Biophysics Journal. 49:809-818
Analytical ultracentrifugation (AUC) has emerged as a robust and reliable technique for biomolecular characterization with extraordinary sensitivity. AUC is widely used to study purity, conformational changes, biomolecular interactions, and stoichiom
Publikováno v:
International journal of biological macromolecules. 209
Breast cancer type 2 susceptibility (BRCA2) protein plays an essential role in the repair mechanism of DNA double-strand breaks and interstrand cross-links by Homologous recombination. Germline mutations identified in the BRCA2 gene confer an increas
Autor:
Nachimuthu Senthil Kumar, Rajan Kumar Choudhary, Nikhil Gadewal, Ekaterina S. Kuligina, M. Quadir Siddiqui, Ashok K. Varma
Publikováno v:
RSC Advances. 8:34056-34068
The BRCT domain of BARD1 (BARD1 BRCT) is involved in many cellular processes such as DNA damage repair (DDR) and cell-cycle checkpoint regulation. BARD1 BRCT performs tumor suppressor function by recruiting BRCA1 at DNA damage site via interactions w
Autor:
Mayank Maheshwari, Rituraj Konwar, Jayanta Sarkar, M. Quadir Siddiqui, L. Ravithej Singh, Hamidullah, Raghib Ashraf, Koneni V. Sashidhara, Praveen Pandey, Mohammad Hasanain
Publikováno v:
Scientific Reports
S009-131, a coumarin-chalcone hybrid, had been shown to possess anti-proliferative and anti-tumour effect by triggering apoptosis. In this report, we investigated role of DNA damage signalling pathway in S009-131 induced cancer cell death. Here we sh