Zobrazeno 1 - 10
of 376
pro vyhledávání: '"M. Pullen"'
Autor:
Nikolaos Meimetis, Krista M. Pullen, Daniel Y. Zhu, Avlant Nilsson, Trong Nghia Hoang, Sara Magliacane, Douglas A. Lauffenburger
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract The development of therapeutics and vaccines for human diseases requires a systematic understanding of human biology. Although animal and in vitro culture models can elucidate some disease mechanisms, they typically fail to adequately recapi
Externí odkaz:
https://doaj.org/article/d709836e3f53497f9d22e8848afa7d5b
Autor:
Molly F. Parsons, Matthew F. Allan, Shanshan Li, Tyson R. Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M. Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Hybrid nucleic acid origami has potential for biomedical delivery of mRNA and fabrication of artificial ribozymes. Here, the authors use chemical footprinting and cryo-electron microscopy to reveal insights into nucleic acid origami used to fold mess
Externí odkaz:
https://doaj.org/article/108ab9faee2848f09c545c0415482066
Autor:
Matthew J. Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L. Zhu, Caroline Atyeo, Krista M. Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jr., Jing-Hui Tian, Dansu Yuan, Kathryn A. Bowman, Bin Zhou, Sonia Maciejewski, Marisa E. McGrath, James Logue, Matthew B. Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A. Lauffenburger, Ann M. Greene, Alyse D. Portnoff, Michael J. Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100405- (2021)
Summary: Recently approved vaccines have shown remarkable efficacy in limiting SARS-CoV-2-associated disease. However, with the variety of vaccines, immunization strategies, and waning antibody titers, defining the correlates of immunity across a spe
Externí odkaz:
https://doaj.org/article/4986517e15404f80baa1ac1f4714b268
Autor:
Jingli Wang, William R. Wilson, Susan M. Pullen, Jiechuang Su, Huai-Ling Hsu, Francis W. Hunter
Supplementary Figures. Supplementary Figures including correlations of HAP sensitivity between cell lines, development and characterisation of doxycycline-inducible shRNA cell lines, and effect of BRCA2 knockout on radiation sensitivity of DLD-1 tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5024b37df1574f0ecb36039cae084bf4
https://doi.org/10.1158/1535-7163.22502809
https://doi.org/10.1158/1535-7163.22502809
Autor:
Jingli Wang, William R. Wilson, Susan M. Pullen, Jiechuang Su, Huai-Ling Hsu, Francis W. Hunter
Supplementary Tables. Supplementary Tables (including statistical analysis of relationships between one-electron reductase activity, HR status and chemosensitivity) and supplementary references related to this material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b74e544cf3021c52e6a78e33361d5e
https://doi.org/10.1158/1535-7163.22502806.v1
https://doi.org/10.1158/1535-7163.22502806.v1
Autor:
William R. Wilson, Adam V. Patterson, J. Martin Brown, Mary J. Dorie, Susan M. Pullen, Dianne M. Ferry, Christopher P. Guise, Rachelle S. Singleton
Supplementary Figure 4 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ec07e6ed7b40b3c4fb91a36d3c8c2e
https://doi.org/10.1158/0008-5472.22380690.v1
https://doi.org/10.1158/0008-5472.22380690.v1
Autor:
William R. Wilson, Adam V. Patterson, J. Martin Brown, Mary J. Dorie, Susan M. Pullen, Dianne M. Ferry, Christopher P. Guise, Rachelle S. Singleton
Supplementary Figure 1 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e68e54bf42ad26ebe3cd4e0175a32bc
https://doi.org/10.1158/0008-5472.22380699
https://doi.org/10.1158/0008-5472.22380699
Autor:
William R. Wilson, Adam V. Patterson, J. Martin Brown, Mary J. Dorie, Susan M. Pullen, Dianne M. Ferry, Christopher P. Guise, Rachelle S. Singleton
PR-104, currently in clinical trial, is converted systemically to the dinitrobenzamide nitrogen mustard prodrug PR-104A, which is reduced selectively in hypoxic cells to cytotoxic hydroxylamine (PR-104H) and amine (PR-104M) metabolites. Here, we eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::975719a47c895fc2558b0bca06631134
https://doi.org/10.1158/0008-5472.c.6499647.v1
https://doi.org/10.1158/0008-5472.c.6499647.v1
Autor:
William R. Wilson, Adam V. Patterson, J. Martin Brown, Mary J. Dorie, Susan M. Pullen, Dianne M. Ferry, Christopher P. Guise, Rachelle S. Singleton
Supplementary Figure 2 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960baa38d22650786272fd3fe84063a4
https://doi.org/10.1158/0008-5472.22380696.v1
https://doi.org/10.1158/0008-5472.22380696.v1
Autor:
William R. Wilson, Adam V. Patterson, J. Martin Brown, Mary J. Dorie, Susan M. Pullen, Dianne M. Ferry, Christopher P. Guise, Rachelle S. Singleton
Supplementary Table 1 from DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59de3e4968793904bae6b6f70ab587ef
https://doi.org/10.1158/0008-5472.22380684
https://doi.org/10.1158/0008-5472.22380684