Quantitation of putative activator-target affinities predicts transcriptional activating potentials

Autor: Y, Wu, R J, Reece, M, Ptashne

Publikováno v: The EMBO journal. 15(15)

We quantitate the 'activating potentials' of deletion and point mutation variants of a 42 amino acid yeast transcriptional activating region excised from the yeast activator GAL4 and, using surface plasmon resonance, we measure the relative affinitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5dee3a072d5c81bf3c21b83aba10a3a
https://pubmed.ncbi.nlm.nih.gov/8670900

Regulation of transcription of genes

Autor: M. Ptashne

Publikováno v: Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 349:255-255

The principles of the mechanism of gene regulation as elucidated for prokaryotes apply in outline to the eukaryotic as well. For example, the mechanisms of protein-DNA interactions are similar and in some cases highly conserved throughout evolution.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86da851a6bbc39209f0fa16e5da96a3b
https://doi.org/10.1098/rstb.1995.0110

DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae

Autor: Roger Brent, Pamela A. Silver, M Ptashne

Publikováno v: Molecular and Cellular Biology. 6:4763-4766

We showed by immunofluorescence that the procaryotic DNA-binding protein LexA and a chimeric protein that contains the DNA-binding portion of LexA (amino acids 1 to 87) and a large portion (amino acids 74 to 881) of the Saccharomyces cerevisiae posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a342b68ec670d1d6c1b76ad5a582df3
https://doi.org/10.1128/mcb.6.12.4763

Patents and literature

Autor: M. E. Long, C. K. Lee, W. L. Griffith, A. L. Compere, J. W. Holleman, L. G. Simonson, B. L. Lamberts, D. M. Fenton, J. Goldstein, E. C. Dawson, J. D. H. Roman, B. K. Van Weemen, E. Matsumura, H. lshikawa, H. Misaki, M. W. Griffiths, D. D. Muir, J. D. Phillips, H. Gauhl, G. Schawohl, H. Seidel, K. Beaucamp, S. Johal, B. E. Norman, O. Terada, K. Aisaka, J. R. Teague, A. L. Huebner, D. F. Hershberger, M. M. Sternberg, J. Shimizu, K. Suzuki, Y. Nakajima, I. J. Higgins, K. D. Spence, R. E. Andrews, E. Peel, C. C. Dalton, J. H. Litchfield, W. T. Lawhon, H. Nakajima, K. Nagata, M. Kageyma, T. Suga, T. Suzuki, K. Motosugi, T. Sozzi, A. Schrenk, M. Buhler, R. A. Rosenberg, C. S. Gong, L. F. Chen, G. T. Tsao, R. Kurane, Y. Takahara, F. J. Carduck, D. Kloetzer, G. Veldman, W. R. Tolbert, M. M. Hitt, J. Feder, R. C. Kimes, W. Hartmeier, P. J. Senior, L. F. Wright, B. Alderson, H. Yukawa, T. Nara, Y. Takayama, F. W. Hayes, W. P. Weisrock, M. H. Updike, G. J. Calton, R. G. Cox, D. C. Steer, G. R. Lawford, P. N. Lewis, R. L. Whistler, H. Nakazawa, I. Yamane, E. Akutsu, R. E. Heady, Y. Assai, M. Shimada, K. Soda, K. A. Powell, B. A. Collinson, W. C. Muller, F. D. Miller, H. Iizuka, Y. Nakamura, P. P. Hung, S. G. Lee, M. Ptashne, G. D. Lauer, T. M. Roberts, K. C. Backman, F. Reusser, J. J. Manis, K. Highlander, T. J. Silhavy, H. A. Shuman, J. Beckwith, M. Schwartz, H. Sugano, D. G. Kleid, D. G. Yansura, H. L. Heyneken, G. F. Miozzari

Publikováno v: Applied Biochemistry and Biotechnology. 8:69-84

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de2690f47202245196e9a7111cf71147
https://doi.org/10.1007/bf02798349

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