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Slow Waning of Antibodies Following BNT162b2 as a Third Dose in Adults Who Had Previously Received 2 Doses of Inactivated Vaccine

Autor: Benjamin J Cowling, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Karl C K Chan, John K C Li, Lison W C Fung, Leo L H Luk, Leo C H Tsang, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Nancy H L Leung

Publikováno v: The Journal of Infectious Diseases. 227:251-255

We administered BNT162b2 as a third dose to 314 adults aged ≥30 years who had previously received 2 doses of inactivated vaccine. We collected blood samples before the third dose and again after 1 month and 6 months, and found robust antibody respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96ba5b0046a1e8e490e0bcb869941996
https://doi.org/10.1093/infdis/jiac380

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Reduced Pathogenicity and Transmission Potential of Omicron BA.1 and BA.2 Sublineages Compared with the Early Severe Acute Respiratory Syndrome Coronavirus 2 D614G Variant in Syrian Hamsters

Autor: Wen Su, Ka Tim Choy, Haogao Gu, Sin Fun Sia, Ka Man Cheng, Sarea Islam Nuha Nizami, Pavithra Krishnan, Yuet Mai Ng, Lydia Dai Jia Chang, Yingzhi Liu, Samuel M S Cheng, Malik Peiris, Leo L M Poon, John M Nicholls, Hui-Ling Yen

Publikováno v: The Journal of Infectious Diseases. 227:1143-1152

Background The epidemiological advantage of Omicron variant is evidenced by its rapid spread and the ability to outcompete prior variants. Among Omicron sublineages, early outbreaks were dominated by BA.1, while BA.2 has gained dominance since Februa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::711ea1eb424078ec619774a521cc80f6
https://doi.org/10.1093/infdis/jiac276

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Lexicon-Based Sentiment Convolutional Neural Networks for Online Review Analysis

Autor: Yanghui Rao, Haoran Xie, Yuwei Liu, Minghui Huang, Leonard K. M. Poon, Fu Lee Wang

Publikováno v: IEEE Transactions on Affective Computing. 13:1337-1348

With the growing availability and popularity of sentiment-rich resources like blogs and online reviews, new opportunities and challenges have emerged regarding the identification, extraction, and organization of sentiments from user-generated documen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb62397c63764147df7b9feeacdd5b2d
https://doi.org/10.1109/taffc.2020.2997769

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Immunogenicity of a Third Dose of BNT162b2 to Ancestral Severe Acute Respiratory Syndrome Coronavirus 2 and the Omicron Variant in Adults Who Received 2 Doses of Inactivated Vaccine

Autor: Nancy H L Leung, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Yvonne Y Ng, Leo L H Luk, Karl C K Chan, John K C Li, Yonna W Y Leung, Leo C H Tsang, Sara Chaothai, Kelvin K H Kwan, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Benjamin J Cowling

Publikováno v: Clinical Infectious Diseases. 76:e299-e307

Background Limited data exist on antibody responses to mixed vaccination strategies that involve inactivated coronavirus disease 2019 (COVID-19) vaccines, particularly in the context of emerging variants. Methods We conducted an open-label trial of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52930cde3dc79c643f8185d8ebad0120
https://doi.org/10.1093/cid/ciac458

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Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong

Publikováno v: Nature Communications. 14

After keeping infections at bay for two years, Hong Kong experienced a surge of Omicron BA.2 infections in early 2022 that overwhelmed the health care system, isolation facilities, and contact tracing capacity, leading to one of the highest per-capit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeefd13234a448c206d2d5b12d811ae
https://doi.org/10.1038/s41467-023-38201-5

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Within-host genetic diversity of SARS-CoV-2 lineages in unvaccinated and vaccinated individuals

Autor: Haogao Gu, Ahmed Abdul Quadeer, Pavithra Krishnan, Daisy Y. M. Ng, Lydia D. J. Chang, Gigi Y. Z. Liu, Samuel M. S. Cheng, Tommy T. Y. Lam, Malik Peiris, Matthew R. McKay, Leo L. M. Poon

Publikováno v: Nature Communications. 14

Viral and host factors can shape SARS-CoV-2 evolution. However, little is known about lineage-specific and vaccination-specific mutations that occur within individuals. Here, we analysed deep sequencing data from 2,820 SARS-CoV-2 respiratory samples

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ed9f8c05bad60275c16603b65336e05
https://doi.org/10.1038/s41467-023-37468-y

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