Zobrazeno 1 - 10
of 526
pro vyhledávání: '"M. Ponec"'
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 11, Pp 1759-1770 (2001)
The lipid regions in the outermost layer of the skin (stratum corneum) form the main barrier for diffusion of substances through the skin. In this layer the main lipid classes are ceramides, cholesterol (CHOL), and FFA. Previous studies revealed a co
Externí odkaz:
https://doaj.org/article/7f6af13ec1cd474587f388be63966ce0
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 12, Pp 2303-2312 (1999)
Abstract The main diffusion barrier for drugs penetrating through the skin is located in the intercellular lipid matrix in the upper layer of the skin, the stratum corneum (SC). The main lipid classes in the SC are ceramides (CER), free fatty acids (
Externí odkaz:
https://doaj.org/article/f28100bbe5c74e4cbcf1c6bee0a66c43
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 186-196 (1998)
The main barrier of the skin is formed by the lipids in the apical skin layer, the stratum corneum (SC). In SC mainly ceramides (CER), free fatty acids (FFA) and cholesterol (CHOL) are present. The CER are composed of at least six different fractions
Externí odkaz:
https://doaj.org/article/1759cfd304984d8481957c4a7bee70dd
Publikováno v:
Current Breast Cancer Reports. 9:188-194
Breast cancer treatment continues to evolve as targeted therapeutic strategies are developed for the various molecular subtypes of breast cancer. The PARP inhibitors represent a novel targeted therapy for tumors with defective homologous recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be19b9ee0c2fa5240e565e4d1bd5153
https://doi.org/10.1007/s12609-017-0251-x
https://doi.org/10.1007/s12609-017-0251-x
Autor:
M. Luisa Iruela-Arispe, Kevin C. Chen, Jennifer J. Hofmann, Judith C. Gasson, Timothy C. Cox, Ryan M. Ponec, Ann C. Zovein, Kirsten A. Turlo, Maureen Lynch
Publikováno v:
Blood
The vitelline artery is a temporary structure that undergoes extensive remodeling during midgestation to eventually become the superior mesenteric artery (also called the cranial mesenteric artery, in the mouse). Here we show that, during this remode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa4907603177f6d31a8a56291b5765f
https://doi.org/10.1182/blood-2010-04-279497
https://doi.org/10.1182/blood-2010-04-279497
Autor:
J, van de Sandt, R, Roguet, C, Cohen, D, Esdaile, M, Ponec, E, Corsini, C, Barker, N, Fusenig, M, Liebsch, D, Benford, A de B, de Fraissinette, M, Fartasch
Publikováno v:
Alternatives to laboratory animals : ATLA. 27(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e49d607d04b28b6a2aa26069771b6331
https://pubmed.ncbi.nlm.nih.gov/25490286
https://pubmed.ncbi.nlm.nih.gov/25490286
Publikováno v:
Food and Chemical Toxicology. 40:573-592
The dermatotoxicologist today is faced with a dilemma. Protection of workers and consumers from skin toxicities (irritation and allergy) associated with exposure to products, and the ingredients they contain, requires toxicological skin testing prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ceaa9fa3b176045610e95c4d744972
https://doi.org/10.1016/s0278-6915(02)00005-4
https://doi.org/10.1016/s0278-6915(02)00005-4
Publikováno v:
Melanoma Research. 10:127-140
The growth patterns and morphological phenotype of four human melanoma cell lines with different metastatic potentials were investigated in submerged and in air-exposed (skin equivalent) keratinocyte-melanoma cell co-cultures. In contrast to the subm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0236435dcdc4333c7662f3081e7012d6
https://doi.org/10.1097/00008390-200004000-00005
https://doi.org/10.1097/00008390-200004000-00005
Publikováno v:
Journal of biological physics. 28(2)
The superficial layer of the skin, the stratum corneum, is the main barrier for diffusion of substances across the skin. The stratum corneum is composed of corneocytes embedded in lipid lamellae. In previous studies two lamellar phases have been iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76119978aebf06b7af525f1f30a2522e
https://pubmed.ncbi.nlm.nih.gov/23345770
https://pubmed.ncbi.nlm.nih.gov/23345770