Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. Pilar D'ocon"'
Autor:
M. Antonia Noguera, M. Pilar D'ocon, Cristina Arce, Eduardo Oliver, Nicla Flacco, M. Dolores Ivorra
Publikováno v:
Journal of Vascular Research. 51:209-220
This work compares the expression of adrenoceptors (ARs) and G-protein-coupled receptor kinase (GRK) 2 (RT-PCR and immunoblotting) and functional responses in conductance (aorta) and resistance vessels (mesenteric resistance arteries; MRA) in two dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea211bde7b2e471ca87d9675a4a993c9
https://doi.org/10.1159/000360400
https://doi.org/10.1159/000360400
Simplified Tetrandrine Congeners as Possible Antihypertensive Agents with a Dual Mechanism of Action
Autor:
M. Dolores Ivorra, Raquel Miquel, Bruce K. Cassels, M. Pilar D'ocon, Patricio Iturriaga-Vásquez
Publikováno v:
Journal of Natural Products. 66:954-957
A series of O- and/or N-substituted derivatives of (+/-)-coclaurine (1a) were synthesized as simplified structural mimics of the antihypertensive alkaloid tetrandrine (2) and assayed for binding to brain cortical sites labeled with the alpha(1)-adren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e321ae3548c51f6e30c8ff0a54c47b9
https://doi.org/10.1021/np030022+
https://doi.org/10.1021/np030022+
Autor:
Eduardo, Oliver, Nicla, Flacco, Cristina, Arce, M Dolores, Ivorra, M Pilar, D'Ocon, M Antonia, Noguera
Publikováno v:
Journal of vascular research. 51(3)
This work compares the expression of adrenoceptors (ARs) and G-protein-coupled receptor kinase (GRK) 2 (RT-PCR and immunoblotting) and functional responses in conductance (aorta) and resistance vessels (mesenteric resistance arteries; MRA) in two dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b96fa60ce90caf1af8a95f8420b0b633
https://pubmed.ncbi.nlm.nih.gov/24942010
https://pubmed.ncbi.nlm.nih.gov/24942010
Autor:
Emmanuel Naline, Susana Chuliá, Charles Advenier, M. Pilar D'ocon, M. Antonia Noguera, Joelle Moreau, M. Dolores Ivorra
Publikováno v:
British Journal of Pharmacology. 119:1305-1312
1. The cardiovascular activity of S-(+)-boldine, an aporphine alkaloid structurally related to papaverine, was determined. The work includes functional studies on guinea-pig isolated aorta contracted with noradrenaline, caffeine, KCl or Ca2+, and on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434502c410fc7a7ecd98696656104da5
https://doi.org/10.1111/j.1476-5381.1996.tb16039.x
https://doi.org/10.1111/j.1476-5381.1996.tb16039.x
Publikováno v:
Journal of the Chilean Chemical Society v.51 n.3 2006
SciELO Chile
CONICYT Chile
instacron:CONICYT
Journal of the Chilean Chemical Society, Volume: 51, Issue: 3, Pages: 935-937, Published: SEP 2006
SciELO Chile
CONICYT Chile
instacron:CONICYT
Journal of the Chilean Chemical Society, Volume: 51, Issue: 3, Pages: 935-937, Published: SEP 2006
Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity of these compounds for α 1 -a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64db048e9d863a00d22052a7b3018e7
https://doi.org/10.4067/s0717-97072006000300001
https://doi.org/10.4067/s0717-97072006000300001
Simplified tetrandrine congeners as possible antihypertensive agents with a dual mechanism of action
Autor:
Patricio, Iturriaga-Vásquez, Raquel, Miquel, M Dolores, Ivorra, M Pilar, D'Ocon, Bruce K, Cassels
Publikováno v:
Journal of natural products. 66(7)
A series of O- and/or N-substituted derivatives of (+/-)-coclaurine (1a) were synthesized as simplified structural mimics of the antihypertensive alkaloid tetrandrine (2) and assayed for binding to brain cortical sites labeled with the alpha(1)-adren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89c154110d9ff795b9190cad50ffb228
https://pubmed.ncbi.nlm.nih.gov/12880313
https://pubmed.ncbi.nlm.nih.gov/12880313
Autor:
M. Antonia Noguera, M. Pilar D'ocon
1. Noradrenaline 1 microM induced a contractile response in rat isolated aorta in the presence or in the absence of extracellular Ca2+ with depletion of intracellular Ca2+ stores. Thereafter, during incubation in the presence of Ca2+, an increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eb6a7be4987459a7704c4145b36757
https://europepmc.org/articles/PMC2175951/
https://europepmc.org/articles/PMC2175951/
Autor:
M. Antonia Noguera, M. Pilar D'ocon
Publikováno v:
The Journal of pharmacy and pharmacology. 45(8)
Acute withdrawal of external Mg2+ increased basal tone of rat isolated aorta incubated in the presence of Ca2+. Above normal levels of Mg2+ (1–4 Mm) inhibited basal tone while much higher levels of the divalent cation (64–256 Mm) evoked contracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd1fe054e2af0deb22654832498dc3d
https://pubmed.ncbi.nlm.nih.gov/7901366
https://pubmed.ncbi.nlm.nih.gov/7901366
Publikováno v:
European journal of pharmacology. 231(2)
Contractions evoked by noradrenaline (1 μM) or a depolarizing solution of 60 mM KCI were concentration dependently depressed by the aporphine alkaloids (S)-boldine and (R)-apomorphine in rataorta. Both drugs had a greater inhibitory potency on the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d2e8c04dcc51092733d07805945a01
https://pubmed.ncbi.nlm.nih.gov/8384112
https://pubmed.ncbi.nlm.nih.gov/8384112
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.