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Akademický článek

Inhibition of tyrosine kinase Fgr prevents radiation-induced pulmonary fibrosis (RIPF)

Autor: Amitava Mukherjee, Michael W. Epperly, Renee Fisher, Wen Hou, Donna Shields, M. Saiful Huq, Phillip M. Pifer, Ria Mulherkar, Tyler J. Wilhite, Hong Wang, Peter Wipf, Joel S. Greenberger

Publikováno v: Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)

Abstract Cellular senescence is involved in the development of pulmonary fibrosis as well as in lung tissue repair and regeneration. Therefore, a strategy of removal of senescent cells by senolytic drugs may not produce the desired therapeutic result

Externí odkaz: https://doaj.org/article/b26d0e1944c94d44b7aaa72439d312ac

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Akademický článek

Metabolic targeting, immunotherapy and radiation in locally advanced non-small cell lung cancer: Where do we go from here?

Autor: Annika Dhawan, Phillip M. Pifer, Vlad C. Sandulache, Heath D. Skinner

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

In the US, there are ~250,000 new lung cancer diagnoses and ~130,000 deaths per year, and worldwide there are an estimated 1.6 million deaths per year from this deadly disease. Lung cancer is the most common cause of cancer death worldwide, and it ac

Externí odkaz: https://doaj.org/article/203cac6cf9934343b84723ffd84e2cfd

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