Zobrazeno 1 - 10
of 131
pro vyhledávání: '"M. Pickart"'
Publikováno v:
BioTechniques, Vol 27, Iss 5, Pp 950-954 (1999)
The arginine codon AGA is rarely used in E. coli but is common in eukaryotic genes. Prior studies have shown that the low level of tRNAUCUArg can lead to low expression and misincorporation of lysine for arginine, during expression of genes containin
Externí odkaz:
https://doaj.org/article/5eadb304a60d42b5bb0335b24364e066
Autor:
Stephen N. Thibodeau, Melissa C. Larson, Ellen L. Goode, Jessica R. Balcom, Matthew J. Ferber, Shannon K. McDonnell, Steven Gallinger, Noralane M. Lindor, Yan W. Asmann, Sumit Middha, Polly A. Newcomb, Angela M. Pickart, Lindsey A. Waltman, Daniel D. Buchanan, Christophe Rosty, Shanaka R. Gunawardena, Shaun M. Riska, Mark Clendenning, Aung Ko Win, Loic Le Marchand, Zachary C. Fogarty, Bruce W. Eckloff, Melissa S. DeRycke, Robert W. Haile, Amy J. French, John L. Hopper
Publikováno v:
Molecular Genetics & Genomic Medicine
Background Mutations in several genes predispose to colorectal cancer. Genetic testing for hereditary colorectal cancer syndromes was previously limited to single gene tests; thus, only a very limited number of genes were tested, and rarely those inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e8cdd26ae58b0a7bd2ff780125895b
https://doi.org/10.1002/mgg3.317
https://doi.org/10.1002/mgg3.317
Autor:
Angelo Peschiaroli, Y Amy Lam, Cecile M Pickart, Nickolai A Barlev, Gerry Melino, Francesca Bernassola
Publikováno v:
eLS. :1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b66b1678fb880d45396b191bb22bf00
https://doi.org/10.1002/9780470015902.a0000685.pub2
https://doi.org/10.1002/9780470015902.a0000685.pub2
Autor:
Luming Yin, Keith D. Wilkinson, Cecile M. Pickart, Cynthia Wolberger, David Fushman, Seth W. Dickey, Tao Wang, Eric M. Cooper, Robert E. Cohen, Ming Yih Lai
Publikováno v:
Journal of Molecular Biology. 386:1011-1023
Otubain 1 belongs to the ovarian tumor (OTU) domain class of cysteine protease deubiquitinating enzymes. We show here that human otubain 1 (hOtu1) is highly linkage-specific, cleaving Lys48 (K48)-linked polyubiquitin but not K63-, K29-, K6-, or K11-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04da153e61e6991177b510b0c9956eed
https://doi.org/10.1016/j.jmb.2008.12.085
https://doi.org/10.1016/j.jmb.2008.12.085
Akademický článek
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Autor:
Dongren Yang, Angela S. Howard, Donald A. Bruun, Mispa Ajua-Alemanj, Cecile M. Pickart, Pamela J. Lein
Publikováno v:
Toxicology and Applied Pharmacology. 228:32-41
A primary role of acetylcholinesterase (AChE) is regulation of cholinergic neurotransmission by hydrolysis of synaptic acetylcholine. In the developing nervous system, however, AChE also functions as a morphogenic factor to promote axonal growth. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dee6083e4f322b27b601c7c393d0130
https://doi.org/10.1016/j.taap.2007.11.005
https://doi.org/10.1016/j.taap.2007.11.005
Publikováno v:
Journal of Molecular Biology. 367:204-211
Ubiquitin modification of proteins is used as a signal in many cellular processes. Lysine side-chains can be modified by a single ubiquitin or by a polyubiquitin chain, which is defined by an isopeptide bond between the C terminus of one ubiquitin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff52703ab9c7625127de9f86a5a929c0
https://doi.org/10.1016/j.jmb.2006.12.065
https://doi.org/10.1016/j.jmb.2006.12.065
Autor:
Matthew C. Steele, Enid E. Martinez, Ariel Stanhill, Guangwei Min, Xiang-Peng Kong, Cole M. Haynes, Yuhong Zhang, Juliya Kalinina, Cecile M. Pickart, David Ron
Publikováno v:
Molecular Cell. 23:875-885
Protein misfolding caused by exposure to arsenite is associated with transcriptional activation of the AIRAP gene. We report here that AIRAP is an arsenite-inducible subunit of the proteasome's 19S cap that binds near PSMD2 at the 19S base. Compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2423502e9e35916376e42fdabadcc4ea
https://doi.org/10.1016/j.molcel.2006.07.023
https://doi.org/10.1016/j.molcel.2006.07.023
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11589-11594
In cells expressing human cytomegalovirus US11 protein, newly synthesized MHC class I heavy chains (HCs) are rapidly dislocated from the endoplasmic reticulum (ER) and degraded in the cytosol, a process that is similar to ER-associated degradation (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd6fa94e01f388d993d233fdab68530
https://doi.org/10.1073/pnas.0605215103
https://doi.org/10.1073/pnas.0605215103
Publikováno v:
Analytical Chemistry. 78:3681-3687
We report here the application of electrospray ionization tandem mass spectrometry for the characterization of protein ubiquitylation, an important posttranslational modification of cellular proteins. Trypsin digestion of ubiquitin-conjugated protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0cbda4ce259b9dc21f16391009aa38
https://doi.org/10.1021/ac051904b
https://doi.org/10.1021/ac051904b