Zobrazeno 1 - 10
of 248
pro vyhledávání: '"M. Pfahl"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of Biological Chemistry. 271:22441-22446
Retinoids have shown promise as anti-cancer and cancer preventative agents. All-trans-N-(4-hydroxyphenyl)retinamide (4HPR) belongs to a new group of retinoids that not only inhibit the proliferation of cancer cells but also can induce apoptosis in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92683572cfe2e4c279dc472fe8453404
https://doi.org/10.1074/jbc.271.37.22441
https://doi.org/10.1074/jbc.271.37.22441
Autor:
MI Dawson, R Morosetti, S Pakkala, W Chao, Hironori Ueno, Y. Ikeda, DL Chen, HP Koeffler, M Morikawa, M Pfahl, Masahiro Kizaki, E Elster, R Heyman, D Heber
Publikováno v:
Scopus-Elsevier
The biologic effects of retinoids such as all-trans-retinoic acid (ATRA) and 9-cis-retinoic acid on proliferation and differentiation of hematopoietic cells are mediated by binding and activating two distinct families of transcription factors: the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107b232f2f2ed92388aafbaaecbf9bf4
https://doi.org/10.1182/blood.v87.5.1977.1977
https://doi.org/10.1182/blood.v87.5.1977.1977
Publikováno v:
Biochemical and Biophysical Research Communications. 211:83-91
Recently, we reported the cloning and characterization of the novel orphan receptor TAK1. In this study, we analyze the interaction of TAK1 with a variety of response elements (RE′s) and demonstrate that TAK1 binds effectively to RE′s composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2660a9fae889011f4908049d2db1bf
https://doi.org/10.1006/bbrc.1995.1781
https://doi.org/10.1006/bbrc.1995.1781
Autor:
M. Pfahl, N. Dean, C. Liu, D. Mercola, Y. M. Yang, W. Charbono, R. Mckay, O. Potapova, F. Bost, X. P. Lu
Publikováno v:
Insulin & Related Proteins-Structure to Function and Pharmacology ISBN: 9781402006555
Recent studies have revealed that the alternate Map Kinase pathway, termed the Jun Kinase pathway, is commonly activated by the Epidermal Growth Factor and Serum in a variety of human tumor lines, especially prostate carcinoma. This pathway activates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0542124efa3ecc4ce7e0f93eea00211d
https://doi.org/10.1007/0-306-47582-0_17
https://doi.org/10.1007/0-306-47582-0_17
Publikováno v:
Cancer research. 61(23)
Retinoid-related molecules have been described that induce apoptosis in a variety of cancer cell lines. Of particular interest is the apoptotic activity of the all-trans-retinoic acid receptor gamma-selective molecules MX2870-1 and MX3350-1. These co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f812a273dc62ae11bbebbacb33fe2aa9
https://pubmed.ncbi.nlm.nih.gov/11731435
https://pubmed.ncbi.nlm.nih.gov/11731435
Publikováno v:
Cancer research. 58(21)
Endothelin-1 (ET-1) is not only a potent vasoconstrictor but also serves as an important growth stimulator in various cancers, including breast, cervical, pancreatic, and prostate cancer. This suggests that blockage of ET-1 production may suppress tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0096e2c2cefcab647c8da3ee603d927
https://pubmed.ncbi.nlm.nih.gov/9809984
https://pubmed.ncbi.nlm.nih.gov/9809984
Publikováno v:
Cancer research. 58(20)
Close to 180,000 women will be diagnosed with breast cancer this year in the United States and more than 43,000 will die from this disease. Antiestrogens have shown promise, but they can only be effective against estrogen-dependent stages of the dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8abea5fd8bec7ed8a6f452e7028baab1
https://pubmed.ncbi.nlm.nih.gov/9788611
https://pubmed.ncbi.nlm.nih.gov/9788611
Autor:
F J Piedrafita, M Pfahl
Publikováno v:
Molecular and Cellular Biology, vol 17, iss 11
Vitamin A and its derivatives, the retinoids, are essential regulators of many important biological functions, including cell growth and differentiation, development, homeostasis, and carcinogenesis. Natural retinoids such as all-trans retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab25c25779a8811065919f2bb85b89f9
https://pubmed.ncbi.nlm.nih.gov/9343396
https://pubmed.ncbi.nlm.nih.gov/9343396