Zobrazeno 1 - 10
of 142
pro vyhledávání: '"M. Pertovaara"'
Autor:
M Korpela, M. Pertovaara
Publikováno v:
Scandinavian Journal of Rheumatology. 48:418-419
Fatigue is one of the most distracting symptoms of primary Sjogren’s syndrome (pSS), which also notably affects the health-related quality of life (1). In an incidence cohort of Swedish pSS patient...
Autor:
Markku Korpela, M. Pertovaara
Publikováno v:
Rheumatology. 53:927-931
Objective. A European League Against Rheumatism (EULAR) SS disease activity index (ESSDAI) and a patient-reported index (ESSPRI) have recently been developed and validated. In our previous study the ESSDAI correlated significantly with serum b2 micro
Publikováno v:
Rheumatology. 50:1453-1457
Objective. Anti-carbonic anhydrase II (anti-CA II) antibodies have been related to renal manifestations of primary SS (pSS), and animal studies have even suggested a pathogenic role for them. However, not all pSS patients with renal tubular acidosis
Autor:
Reetta Huttunen, M. Pertovaara, Janne Aittoniemi, Simo S. Oja, Janne Laine, A. Raitala, Jaana Syrjänen, Risto Vuento, Heini Huhtala, Mikko Hurme
Publikováno v:
Shock. 33:149-154
Indoleamine 2,3-dioxygenase (IDO), which is the rate-limiting enzyme for tryptophan (trp) catabolism, may play a critical role in various inflammatory disorders. Recent studies on trauma patients have suggested that the degradation of trp is associat
Autor:
M. Pertovaara, Markus Juonala, Olli T. Raitakari, Terho Lehtimäki, Tomi Laitinen, Mika Kähönen, Jorma Viikari, M Hurme, L. Taittonen
Publikováno v:
Rheumatology. 48:1553-1556
Objective. There is ample evidence demonstrating that accelerated atherosclerosis prevails in autoimmune rheumatic diseases, particularly in SLE, and that the risk is due not only to traditional cardiovascular risk factors but also to the disease its
Autor:
A. Jula, Markus Juonala, M. Pertovaara, Mika Kähönen, Atte Haarala, Mikko Hurme, Juulia Jylhävä, Jorma Viikari, Terho Lehtimäki, Carita Eklund, Olli T. Raitakari, Risto Huupponen, N. Hutri-Kähönen, Mari Levula
Publikováno v:
Journal of Internal Medicine. 266:286-295
Background. Serum amyloid A (SAA) is a sensitive marker of inflammation and its elevation has been implicated in obesity and in cardiovascular disease, yet data on its regulation in young adults or on its role in early atherosclerosis is scarce. We i
Publikováno v:
Clinical immunology (Orlando, Fla.). 165
Limited data are available regarding the intracellular responses to different cytokines in primary Sjogren's syndrome (pSS). We studied the signal transducer and activator of transcription (STAT) activation profile in response to cytokine stimulation
Autor:
M. Pertovaara, Matti K. Romu, Kalle Aaltonen, J. Joensuu, Dan Nordström, Jukka Lähteenmäki, Hanna E. Hirvonen, Arto V. Heinonen, Marja Blom, Aki K. Similä
Publikováno v:
The Journal of rheumatology. 42(12)
Objective.The aim of this research was to describe the effectiveness and drug survival of tumor necrosis factor (TNF) inhibitors in the treatment of ankylosing spondylitis (AS) and to analyze the effect of concomitant treatment with conventional dise
Publikováno v:
Clinical and experimental immunology. 181(1)
Summary The expression and phosphorylation of signal transducer and activator of transcription-1 (STAT-1) have been shown to be markedly increased in the salivary gland epithelial cells of patients with primary Sjögren's syndrome (pSS). The present
Autor:
A. Raitala, Mika Kähönen, Mikko Hurme, Jorma Viikari, M. Pertovaara, Terho Lehtimäki, Olli T. Raitakari, Markus Juonala
Publikováno v:
Tampere University
Summary There is a growing body of evidence attesting the significance of inflammation in the pathogenesis of atherosclerosis. Protein tyrosine phosphate PTPN22 C/T single nucleotide polymorphism (SNP) at +1858 has been identified recently as a susce