Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M. Paskowitz"'
Publikováno v:
British Journal of Ophthalmology. 90:1060-1066
Light deprivation has long been considered a potential treatment for patients with inherited retinal degenerative diseases, but no therapeutic benefit has been demonstrated to date. In the few clinical studies that have addressed this issue, the unde
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 251:1015-1017
Publikováno v:
The Astrophysical Journal. 565:608-620
We examine the eccentricity evolution of a system of two planets locked in a mean motion resonance, in which the outer planet loses energy and angular momentum. The sink of energy and angular momentum could be either a gas or planetesimal disk. We sh
Publikováno v:
Journal of Molecular Biology. 284:557-568
The activity of the developmental transcription factor sigmaF in Bacillus subtilis is governed by a switch involving the dual function protein SpoIIAB. SpoIIAB is an antisigma factor that forms complexes with sigmaF and with an alternative partner pr
Autor:
Walter J. Stark, James T. Handa, D M Paskowitz, Peter L. Gehlbach, T R Gadek, Diana V. Do, Ovais Shaikh, Quan Dong Nguyen, C Semba, Scott D. Solomon
A growing body of evidence points to a role for inflammation mediated by lymphocyte function-associated antigen-1 (LFA-1) and its ligand intercellular adhesion molecule-1 in the pathogenesis of diabetic macular oedema. This phase 1b clinical trial as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2458d82c6e062082813b153bdf572fbe
https://europepmc.org/articles/PMC3396168/
https://europepmc.org/articles/PMC3396168/
Autor:
John G. Flannery, Haidong Yang, Daniel M. Paskowitz, Dirk Grimm, Douglas Yasumura, Kenneth P. Greenberg, Douglas Vollrath, Jacque L. Duncan, Matthew M. LaVail, Mark A. Kay
Publikováno v:
Human gene therapy. 18(10)
The selective silencing of target genes in specific cell types by RNA interference (RNAi) represents a powerful approach both to gene therapy of dominantly active mutant alleles, and to the investigation of normal gene function in animal models in vi
Autor:
Jacque L. Duncan, Haidong Yang, Michael T. Matthes, Marco A. Zarbin, Matthew M. LaVail, Douglas Yasumura, Daniel M. Paskowitz, George Nune
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Age related macular degeneration (AMD) is the leading cause of blindness among the elderly in the United States (Klein et al., 1992; Klein et al., 2002), and choroidal neovascularization (CNV) accounts for the majority of severe vision loss (Ferris e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a9ac7b163668bb8607f7eb28664b0e
https://doi.org/10.1007/0-387-32442-9_41
https://doi.org/10.1007/0-387-32442-9_41
Autor:
Jacque L, Duncan, Daniel M, Paskowitz, George C, Nune, Douglas, Yasumura, Haidong, Yang, Michael T, Matthes, Marco A, Zarbin, Matthew M, LaVail
Publikováno v:
Advances in experimental medicine and biology. 572
Autor:
Kate Donohue-Rolfe, Michael T. Matthes, Carolyn M Graybeal, Jacque L. Duncan, Douglas Yasumura, Marco A. Zarbin, Haidong Yang, Daniel M. Paskowitz, George Nune, Matthew M. LaVail, Kamran Hosseini
Publikováno v:
Investigative ophthalmologyvisual science. 48(1)
Purpose A prior study showed that brain-derived neurotrophic factor (BDNF) rescues photoreceptors from collateral retinal damage caused by photodynamic therapy (PDT). This study was conducted to determine whether ciliary neurotrophic factor (CNTF), a
Autor:
Daniel M. Paskowitz, Marco A. Zarbin, George Nune, Matthew M. LaVail, Michael T. Matthes, Shivani Sharma, Jacque L. Duncan, Douglas Yasumura, Haidong Yang, Robert B. Bhisitkul
Publikováno v:
Investigative ophthalmologyvisual science. 45(11)
PURPOSE. Verteporfin photodynamic therapy (PDT) is the most effective treatment for age-related macular degeneration, using laser activation of a photosensitizing dye to achieve closure of choroidal neovascularization. Although PDT preferentially aff