Zobrazeno 1 - 10 of 33 pro vyhledávání: '"M. Paraire"'
1
Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation
Autor: Nicholas H. G. Holford, Christian Laveille, M. Francillard, M. Paraire, Nicolas Frey, Roeline Jochemsen
Publikováno v: British Journal of Clinical Pharmacology. 55:147-157
Aims To study the relationship between the pharmacokinetics (PK) of gliclazide and its long-term pharmacodynamic (PD) effect in a large population of Type 2 diabetic patients and to identify factors predicting intersubject variability. Methods A PKPD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e110c8745ea6c78c49aac4c7904fa7ff
https://doi.org/10.1046/j.1365-2125.2003.01751.x
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2
Complete bioavailability and lack of food-effect on pharmacokinetics of gliclazide 30 mg modified release in healthy volunteers
Autor: P. Delrat, R. Jochemsen, M. Paraire
Publikováno v: Biopharmaceutics & Drug Disposition. 23:151-157
A new modified release (MR) formulation containing 30 mg of gliclazide was developed to obtain a better predictable release of the active principle and to allow once-daily dosing regimen. An absolute bioavailability study was carried out to character
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31689f7508e30c5a66c419b79ea992d
https://doi.org/10.1002/bdd.303
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3
Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation
Autor: N, Frey, C, Laveille, M, Paraire, M, Francillard, N H G, Holford, Roeline, Jochemsen
Publikováno v: British journal of clinical pharmacology. 55(2)
To study the relationship between the pharmacokinetics (PK) of gliclazide and its long-term pharmacodynamic (PD) effect in a large population of Type 2 diabetic patients and to identify factors predicting intersubject variability.A PKPD database of 6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab22f2e6342ff05fe46a86b64babae72
https://pubmed.ncbi.nlm.nih.gov/12580986
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8
Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl- 1-(3-(2-chloroethyl)-3-nitrosoureido) ethylphosphonate-S10036
Autor: H, Tapiero, M B, Yin, J, Catalin, M, Paraire, P, Deloffre, Y, Rustum, J P, Bizzari, K D, Tew
Publikováno v: Anticancer research. 9(6)
Fotemustine is a new chloroethylnitrosourea which has recently entered a Phase II clinical trial. Using standard cytotoxicity analyses, Fotemustine was shown to be preferentially active in two Mer- cell lines, human colon BE and human lung A427. Comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a94cb336255e7c77fd7134b14094648
https://pubmed.ncbi.nlm.nih.gov/2627116
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9
Early monitoring of human renal transplantations by N-acetyl-beta-D-glucosaminidase isoenzyme activities in urines
Autor: R, Bourbouze, J C, Gluckman, P, Frantz, M, Paraire, F C, Baumann, J, Luciani, F, Percheron, M, Legrain
Publikováno v: Clinica chimica acta; international journal of clinical chemistry. 149(2-3)
Monitoring of variations in N-acetyl-beta-D-glucosaminidase (NAG) urinary activity, following renal transplantation, has been proposed for the early diagnosis of rejection episodes. In this study, the measurement of urinary NAG-B activity was conduct
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92382cb4e2c881982c7745ec0b568228
https://pubmed.ncbi.nlm.nih.gov/3896578
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10
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