Zobrazeno 1 - 10
of 31
pro vyhledávání: '"M. Paolella"'
Autor:
Lauren M. Paolella, Sarmistha Mukherjee, Cassie M. Tran, Bruna Bellaver, Mindy Hugo, Timothy S. Luongo, Swapnil V. Shewale, Wenyun Lu, Karthikeyani Chellappa, Joseph A. Baur
Publikováno v:
Molecular Metabolism, Vol 32, Iss , Pp 136-147 (2020)
Objective: Pharmacological agents targeting the mTOR complexes are used clinically as immunosuppressants and anticancer agents and can extend the lifespan of model organisms. An undesirable side effect of these drugs is hyperlipidemia. Although multi
Externí odkaz:
https://doaj.org/article/b5faee1960844042ab6ab3295bfd6258
Autor:
Sarmistha Mukherjee, James Mo, Lauren M. Paolella, Caroline E. Perry, Jade Toth, Mindy M. Hugo, Qingwei Chu, Qian Tong, Karthikeyani Chellappa, Joseph A. Baur
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Liver regeneration is critical to survival after traumatic injuries, exposure to hepatotoxins, or surgical interventions, yet the underlying signaling and metabolic pathways remain unclear. In this study, we show that hepatocyte-specific loss of the
Externí odkaz:
https://doaj.org/article/5be476c9f2ad4f45a959b3a77c5bb5e1
Autor:
Antonio Davila, Ling Liu, Karthikeyani Chellappa, Philip Redpath, Eiko Nakamaru-Ogiso, Lauren M Paolella, Zhigang Zhang, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
Publikováno v:
eLife, Vol 7 (2018)
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (N
Externí odkaz:
https://doaj.org/article/27a97775e8b14fa5b714a0c3f98795b2
Autor:
JORDAN W. STROBER, LAUREN M. PAOLELLA, REBECCA SUH, BRANDON T. HUBBARD, SUE MURRAY, DANIEL F. VATNER
Publikováno v:
Diabetes. 71
Increased de novo lipogenesis (DNL) contributes to lipid disturbances prevalent in insulin resistant (IR) subjects, including dyslipidemia and NAFLD; however, the specific carbon sources that maintain DNL during hepatic IR remain unknown. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::634411df1beca540a6c2c377583111ff
https://doi.org/10.2337/db22-224-or
https://doi.org/10.2337/db22-224-or
Autor:
Jade Toth, Sarmistha Mukherjee, Karthikeyani Chellappa, Qingwei Chu, James Mo, Caroline Perry, Lauren M Paolella, Joseph A. Baur, Mindy M Hugo, Qiang Tong
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight, Vol 6, Iss 7 (2021)
Liver regeneration is critical to survival after traumatic injuries, exposure to hepatotoxins, or surgical interventions, yet the underlying signaling and metabolic pathways remain unclear. In this study, we show that hepatocyte-specific loss of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb125375f2ac8d6e3ece0d2fc49fc050
http://europepmc.org/articles/PMC8119200
http://europepmc.org/articles/PMC8119200
Autor:
Sarmistha Mukherjee, Swapnil V. Shewale, Timothy S. Luongo, Bruna Bellaver, Joseph A. Baur, Karthikeyani Chellappa, Cassie M. Tran, Lauren M Paolella, Mindy M Hugo, Wenyun Lu
Publikováno v:
Molecular Metabolism, Vol 32, Iss, Pp 136-147 (2020)
Molecular Metabolism
Molecular Metabolism
Objective Pharmacological agents targeting the mTOR complexes are used clinically as immunosuppressants and anticancer agents and can extend the lifespan of model organisms. An undesirable side effect of these drugs is hyperlipidemia. Although multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa2b9ad7ecb648eeeb2c79dae3a5f00
https://pubmed.ncbi.nlm.nih.gov/32029223
https://pubmed.ncbi.nlm.nih.gov/32029223
Autor:
Zhigang Zhang, Antonio Davila, Eiko Nakamaru-Ogiso, Lauren M Paolella, Marie E. Migaud, Ling Liu, Philip Redpath, Joshua D. Rabinowitz, Karthikeyani Chellappa, Joseph A. Baur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8efa9bdef849dbf4444b95c4a497982
https://doi.org/10.7554/elife.33246.020
https://doi.org/10.7554/elife.33246.020
Autor:
Eiko Nakamaru-Ogiso, Joshua D. Rabinowitz, Zhigang Zhang, Joseph A. Baur, Ling Liu, Antonio Davila, Karthikeyani Chellappa, Lauren M Paolella, Philip Redpath, Marie E. Migaud
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be10e8ce51baadfa2e9bf5cf8c7f0639
http://europepmc.org/articles/PMC6013257
http://europepmc.org/articles/PMC6013257
Autor:
James G. Davis, Sarmistha Mukherjee, Swapnil V. Shewale, Daniel J. Rader, Lauren M Paolella, Edwige Edouard, Cassie M. Tran, Aisha Wilson, Karthikeyani Chellappa, Joseph A. Baur
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d821047edf37c7154a8bc09e73fd442
https://doi.org/10.1096/fasebj.2018.32.1_supplement.536.8
https://doi.org/10.1096/fasebj.2018.32.1_supplement.536.8
Autor:
M. Paolella, E. Young, R. W. Bounds, Raivo Stern, I. Heinmaa, Eva Pavarini, Marina Carravetta
Publikováno v:
Physical Review B. 97
We have studied carbon-doped magnesium diboride nanoparticles using $^{13}\mathrm{C}$ and $^{11}\mathrm{B}$ NMR in the normal and superconducting states. Measurements of the line shape reveal the role of carbon as a flux-pinning center and, combined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a17c77daef25a4290c81fa18232fe37
https://doi.org/10.1103/physrevb.97.014509
https://doi.org/10.1103/physrevb.97.014509