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pro vyhledávání: '"M. Paabøl Andersen"'
Publikováno v:
Psychopharmacology. 178:9-16
Schizophrenic patients have a deficit in prepulse inhibition (PPI) which can be modelled in rats by administration of direct or indirect dopamine (DA) receptor agonists and N-methyl-d-aspartate (NMDA) receptor antagonists. Moreover, antipsychotics re
Autor:
B. Pouzet, M. Paabøl Andersen
Publikováno v:
Psychopharmacology. 156:291-304
Rationale: Dopamine (DA) receptor agonists disrupt the prepulse inhibition (PPI) in rats which is considered to model PPI deficits observed in schizophrenic patients. Many laboratories have demonstrated that both "typical" and "atypical" antipsychoti