Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M. P. van den Heuvel"'
Autor:
E. P. Tissink, A. A. Shadrin, D. van der Meer, N. Parker, G. Hindley, D. Roelfs, O. Frei, C. C. Fan, M. Nagel, T. Nærland, M. Budisteanu, S. Djurovic, L. T. Westlye, M. P. van den Heuvel, D. Posthuma, T. Kaufmann, A. M. Dale, O. A. Andreassen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Genetic pleiotropy is abundant across spatially distributed brain characteristics derived from one neuroimaging modality (e.g. structural, functional or diffusion magnetic resonance imaging [MRI]). A better understanding of pleiotropy across
Externí odkaz:
https://doaj.org/article/203e2f5dc82f421b993ffe55514ea803
Autor:
Evelien A. J. van Genugten, Theresa J. van Lith, Frederik M. A. van den Heuvel, Josee L. van Steenis, Romy M. ten Heggeler, Monique Brink, Laura Rodwell, Frederick J. A. Meijer, Daphne Lobeek, Wanda Hagmolen of ten Have, Frank L. van de Veerdonk, Mihai G. Netea, Mathias Prokop, Robin Nijveldt, Anil M. Tuladhar, Erik H. J. G. Aarntzen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract In coronavirus disease 2019 (COVID-19), endothelial cells play a central role and an inadequate response is associated with vascular complications. PET imaging with gallium-68 labelled RGD-peptide (68Ga-RGD) targets αvβ3 integrin expressio
Externí odkaz:
https://doaj.org/article/bcc7c129c3b34bbd9f343acf94db7819
Autor:
F. M. A. van den Heuvel, M. Bos, G. S. C. Geuzebroek, E. H. J. G. Aarntzen, I. Maat, H. J. Dieker, M. Verkroost, L. Rodwell, J. ten Oever, R. van Crevel, J. Habets, I. J. E. Kouijzer, R. Nijveldt
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Infective endocarditis (IE) is a complex disease for which the European Society of Cardiology guideline recommends a dedicated multidisciplinary endocarditis team (ET) approach since 2015. It is currently unknown whether this ET a
Externí odkaz:
https://doaj.org/article/deff54cab05e4f5796dc22ee72614d7a
Autor:
Evelien G. E. Hurkmans, Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Yvonne M. H. Versleijen-Jonkers, Melissa H. S. Hillebrandt-Roeffen, Johanne M. Groothuismink, Hanneke I. Vos, Winette T. A. van der Graaf, Uta Flucke, Grigor Muradjan, Hendrik W. B. Schreuder, Melanie M. Hagleitner, Han G. Brunner, Hans Gelderblom, Anne-Marie Cleton-Jansen, Henk-Jan Guchelaar, Eveline S. J. M. de Bont, Daan J. Touw, G. Jan Nijhoff, Leontien C. M. Kremer, Huib Caron, Rachael Windsor, Ana Patiño-García, Anna González-Neira, Federica Saletta, Geoff McCowage, Sumanth Nagabushan, Daniel Catchpoole, D. Maroeska W. M. te Loo, Marieke J. H. Coenen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Despite (neo) adjuvant chemotherapy with cisplatin, doxorubicin and methotrexate, some patients with primary osteosarcoma progress during first-line systemic treatment and have a poor prognosis. In this study, we investigated whether pati
Externí odkaz:
https://doaj.org/article/41ddb83527fc4a9bae06e65f39652d1c
Autor:
A. M. van Hulst, E. J. Verwaaijen, M. F. Fiocco, S. M. F. Pluijm, M. A. Grootenhuis, R. Pieters, E. L. T. van den Akker, M. M. van den Heuvel-Eibrink
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as detrimental with respe
Externí odkaz:
https://doaj.org/article/08ba3da1d9554c76bbc077b8c7062f17
Autor:
Karlijn Bouman, Jan T. Groothuis, Jonne Doorduin, Nens van Alfen, Floris E. A. Udink ten Cate, Frederik M. A. van den Heuvel, Robin Nijveldt, Willem C. M. van Tilburg, Stan C. F. M. Buckens, Anne T. M. Dittrich, Jos M. T. Draaisma, Mirian C. H. Janssen, Erik-Jan Kamsteeg, Esmee S. B. van Kleef, Saskia Koene, Jan A. M. Smeitink, Benno Küsters, Florence H. J. van Tienen, Hubert J. M. Smeets, Baziel G. M. van Engelen, Corrie E. Erasmus, Nicol C. Voermans
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background SELENON (SEPN1)-related myopathy (SELENON-RM) is a rare congenital myopathy characterized by slowly progressive proximal muscle weakness, early onset spine rigidity and respiratory insufficiency. A muscular dystrophy caused by mut
Externí odkaz:
https://doaj.org/article/99f6f067662b4ae7948d3919fc82048d
Autor:
A. J. M. Meijer, F. A. Diepstraten, T. Langer, L. Broer, I. K. Domingo, E. Clemens, A. G. Uitterlinden, A. C. H. de Vries, M. van Grotel, W. P. Vermeij, R. A. Ozinga, H. Binder, J. Byrne, E. van Dulmen-den Broeder, M. L. Garrè, D. Grabow, P. Kaatsch, M. Kaiser, L. Kenborg, J. F. Winther, C. Rechnitzer, H. Hasle, T. Kepak, K. Kepakova, W. J. E. Tissing, A. L. F. van der Kooi, L. C. M. Kremer, J. Kruseova, S. M. F. Pluijm, C. E. Kuehni, H. J. H. van der Pal, R. Parfitt, C. Spix, A. Tillmanns, D. Deuster, P. Matulat, G. Calaminus, A. E. Hoetink, S. Elsner, J. Gebauer, R. Haupt, H. Lackner, C. Blattmann, S. J. C. M. M. Neggers, S. R. Rassekh, G. E. B. Wright, B. Brooks, A. P. Nagtegaal, B. I. Drögemöller, C. J. D. Ross, A. P. Bhavsar, A. G. am Zehnhoff-Dinnesen, B. C. Carleton, O. Zolk, M. M. van den Heuvel-Eibrink, the PanCareLIFE Consortium, and the CPNDS Consortium
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract In children with cancer, the heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility. Using a genome-wide association study (GWAS) approach, we identified a genetic variant in TCERG1L (rs893
Externí odkaz:
https://doaj.org/article/1a21ee1f4f0440f184693f4b2b482abf
Autor:
N. Oosterom, M. Fiocco, R. Q. H. Kloos, I. M. van der Sluis, R. Pieters, B. D. van Zelst, D. E. C. Smith, M. M. van den Heuvel-Eibrink, R. de Jonge, S. G. Heil
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background After High-Dose Methotrexate (HD-MTX), folinic acid rescue therapy (Leucovorin) is administered to reduce side effects in pediatric acute lymphoblastic leukemia (ALL) patients. Leucovorin and MTX are structural analogues, possibly
Externí odkaz:
https://doaj.org/article/adb1e98d32e34de4a97a5e539ca4d3ec
Autor:
V G Pluimakers, M van Waas, C W N Looman, M P de Maat, R de Jonge, P Delhanty, M Huisman, F U S Mattace-Raso, M M van den Heuvel-Eibrink, S J C M M Neggers
Publikováno v:
Endocrine Connections, Vol 9, Iss 7, Pp 676-686 (2020)
Purpose: Augmented survival of childhood nephroblastoma and neuroblastoma has increased long-term side effects such as metabolic syndrome (Met S). Risk stratification is difficult after abdominal radiation because waist circumferenc e underestimate
Externí odkaz:
https://doaj.org/article/96f1d7becb514a9a8937c21704424814
Autor:
W. S. M. E. Theelen, O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. van Noesel, D. S. Peeper, M. M. van den Heuvel, K. Schulze
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background The tumor immune microenvironment is a heterogeneous entity. Gene expression analysis allows us to perform comprehensive immunoprofiling and may assist in dissecting the different components of the immune infiltrate. As gene expre
Externí odkaz:
https://doaj.org/article/debbea0e0b5047e685a2c5ef50af7bd0