Výsledky vyhledávání - "M. P. Valikhov"

Study of the Therapeutic Efficiency of Transduced Olfactory Ensheathing Cells in Spinal Cord Cysts

Autor: A. A. Stepanenko, Igor V. Reshetov, O. V. Stepanova, A. V. Chadin, E. K. Karsuntseva, A D Voronova, A. S. Semkina, M P Valikhov, Grigorii Andreevich Fursa, Anastasiia Olegovna Sosnovtseva, Vladimir P. Chekhonin, Pavel Olegovich Vorobyev

Publikováno v: Stem Cells and Development. 31:9-17

Posttraumatic spinal cord cysts are difficult to treat with medication and surgery. Gene- cell therapy is a promising area of treatment for such patients. However, optimal gene-cell construct for this therapy has not been developed. We investigated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac1fad8045e24b3a978869749871cf0
https://doi.org/10.1089/scd.2021.0265

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Intravital imaging of liposome behavior upon repeated administration: A step towards the development of liposomal companion diagnostic for cancer nanotherapy

Autor: Anastasiia V. Lipatova, Alexander G. Majouga, Stepan Vodopyanov, M P Valikhov, Daria M. Potashnikova, Vladimir P. Chekhonin, P. A. Mel’nikov, Maxim A. Abakumov, Anastasiia S Garanina, Daniil A. Vishnevskiy, Kseniya Yu. Vlasova, V.A. Naumenko

Publikováno v: Journal of Controlled Release. 330:244-256

Accumulation of liposomal drugs into human tumors has substantial variability influencing the probability of positive response to the therapy. Therefore, it becomes very important to identify the eligibility of patients for various treatment options.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ad50bfe7e36dbc8f66302178846e85
https://doi.org/10.1016/j.jconrel.2020.12.014

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Preparation of Adhesion Culture of Neural Stem/Progenitor Cells of the Olfactory Mucosa for the Treatment of Spinal Cord Injuries

Autor: Igor V. Reshetov, M P Valikhov, D A Vishnevskii, E. K. Karsuntseva, A D Voronova, O. V. Stepanova, G. A. Fursa, A. V. Chadin, Vladimir P. Chekhonin

Publikováno v: Bulletin of Experimental Biology and Medicine. 170:158-163

In this work, an optimal protocol was developed for obtaining adhesion culture of neural stem/progenitor cells (NSPC) of rat olfactory mucosa. During the development of the protocol, the conditions for cell culturing on adhesion substrates fibronecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11a49bc8a21a0c954597168c724608f
https://doi.org/10.1007/s10517-020-05023-0

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Combined Preparation of Human Olfactory Ensheathing Cells in the Therapy of Post-Traumatic Cysts of the Spinal Cord

Autor: A. S. Semkina, E. K. Karsuntseva, G. A. Fursa, M P Valikhov, A. V. Chadin, A D Voronova, Vladimir P. Chekhonin, Igor V. Reshetov, O. V. Stepanova

Publikováno v: Bulletin of Experimental Biology and Medicine. 169:539-543

In experiments on rats, co-transplantation of olfactory ensheathing cells of the human olfactory mucosa and neural stem/progenitor cells from the same source into post-traumatic cysts of the spinal cord led to improvement of the motor activity of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9dac378ef6a0ee6636e6c712dcf3cf5
https://doi.org/10.1007/s10517-020-04925-3

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Energy Metabolism in Cellular Regenerative Processes: Focus on PPARα

Autor: E V Kurilina, A D Voronova, T G Kulikova, M P Valikhov, Igor V. Reshetov, Gennady T. Sukhikh, O. V. Stepanova, T V Kuznetsova, R S Akchurin

Publikováno v: Bulletin of Experimental Biology and Medicine. 168:658-661

Reduced expression of the key regulator of cardiac metabolism, transcription factor PPARα, in surgical samples of the auricles from patients with coronary heart disease and heart failure was detected by real-time quantitative PCR. These changes indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999b758cc75ed9e5262ef7468a98d3c0
https://doi.org/10.1007/s10517-020-04774-0

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Neural Stem/Progenitor Cells of Human Olfactory Mucosa for the Treatment of Chronic Spinal Cord Injuries

Autor: A D Voronova, A. V. Chadin, M P Valikhov, Vladimir P. Chekhonin, A. S. Semkina, O. V. Stepanova

Publikováno v: Bulletin of Experimental Biology and Medicine. 168:538-541

We studied the efficiency of transplantation of neural stem/progenitor cells from human olfactory mucosa in chronic spinal cord injury. Neural stem/progenitor cells were obtained by a protocol modified by us and transplanted to rats with spinal post-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba02810a39b5c0e67aaa0f97110790b6
https://doi.org/10.1007/s10517-020-04749-1

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Neurotrophin-3 Enhances the Effectiveness of Cell Therapy in Chronic Spinal Cord Injuries

Autor: O V, Stepanova, A D, Voronova, A V, Chadin, G A, Fursa, E K, Karsuntseva, M P, Valikhov, A S, Semkina, I V, Reshetov, V P, Chekhonin

Publikováno v: Bulletin of experimental biology and medicine. 173(1)

Neurotrophin-3 enhances the effectiveness of human olfactory ensheathing cells in improving hind limb mobility in rats with post-traumatic cysts of the spinal cord. Transplantation of olfactory ensheathing cells into spinal cord cysts reduced their s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02808be9268314231e2eaf8a6b37828c
https://pubmed.ncbi.nlm.nih.gov/35622252

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OBTAINING OF CELLULAR PREPARATIONS OF RAT AND HUMAN OLFACTORY MUCOSA AND THEIR INFLUENCE ON THE SIZE OF MODELED SPINAL CORD CYSTALS

Autor: Vladimir P. Chekhonin, A. V. Chadin, E. K. Karsuntseva, O. V. Stepanova, Igor V. Reshetov, G. A. Fursa, M P Valikhov, A.P Semkina

Publikováno v: http://eng.biomos.ru/conference/articles.htm. 1:75-77

Enriched cultures of olfactory ensheathing cells and neural stem/progenitor cells were obtained according to our developed protocols from the olfactory mucosa of rat and human. It has been shown that only transplantation of human and rat olfactory en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6c4347850f53623ec3f0482c441c022
https://doi.org/10.37747/2312-640x-2021-19-75-77

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