Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M. P. Gamcsik"'
Autor:
M P, Gamcsik, M S, Kasibhatla, D J, Adams, J L, Flowers, O M, Colvin, G, Manikumar, M, Wani, M E, Wall, G, Kohlhagen, Y, Pommier
Publikováno v:
Molecular cancer therapeutics. 1(1)
Depletion of glutathione (GSH) in MCF-7 and MDA-MB-231 cell lines by pretreatment with the GSH synthesis inhibitor buthionine sulfoximine potentiated the activity of 10,11-methylenedioxy-20(S)-camptothecin, SN-38 [7-ethyl-10-hydroxy-20(S)-camptotheci
Publikováno v:
Current pharmaceutical design. 5(8)
Resistance to cyclophosphamide therapy continues to be a major reason for treatment failure. This chapter covers some of the mechanisms implicated in resistance to the toxic and mutagenic effects of cyclophosphamide therapy in the laboratory and clin
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 43(5)
We have utilized 13C NMR spectroscopy to investigate glucose metabolism in the mouse insulinoma Beta TC3 cell line. Cells were cultured and examined both as monolayers and entrapped in alginate/poly-L-lysine/alginate beads. Entrapped cultures were te
Publikováno v:
Cancer research. 55(10)
Native human mammary MCF-7 adenocarcinoma cells and a subline displaying resistance to 4-hydroperoxycyclophosphamide, the chemically activated form of cyclophosphamide, were grown as multicellular spheroids or on a collagen sponge matrix and perfused
Publikováno v:
Cancer research. 51(13)
The in vivo 14N nuclear magnetic resonance spectra of s.c. implanted murine radiation induced fibrosarcomas (RIF-1) display narrow resonances assignable to betaine and other trimethylamines and broad resonances due to amino acids and peptides. In 19
Publikováno v:
Journal of Biological Chemistry. 263:19552-19557
High resolution deuterium NMR spectra were obtained from suspensions of five bacterial strains: Escherichia coli, Clostridium perfringens, Klebsiella pneumoniae, Proteus mirabilis, and Staphylococcus aureus. Deuterium-labeled D-glucose at C-1, C-2, a
Autor:
M P Gamcsik, Stephen B. Baylin, F H Hausheer, G Barnett, S N Rao, I J McLennan, P A Kollman, O M Colvin, J D Saxe, B D Nelkin
Publikováno v:
Carcinogenesis. 10(6)
The conformational and energetic consequences of cytosine methylation in eukaryotes related to transcription or formation of chromatin structure are not well understood. Structures of methylated and unmethylated DNA sequences from biologically releva
Autor:
J P G Malthouse, A. I. Scott, M. P. Gamcsik, R. A. Russell, W. U. Primrose, A. S. F. Boyd, N. E. Mackenzie
Publikováno v:
Chemischer Informationsdienst. 15
Publikováno v:
The Journal of biological chemistry. 263(36)
High resolution deuterium NMR spectra were obtained from suspensions of five bacterial strains: Escherichia coli, Clostridium perfringens, Klebsiella pneumoniae, Proteus mirabilis, and Staphylococcus aureus. Deuterium-labeled D-glucose at C-1, C-2, a