Zobrazeno 1 - 10
of 42
pro vyhledávání: '"M. P. Dolan"'
Autor:
Mohammad Shahbazi, Heather E. Wheeler, Gregory T. Armstrong, Robert D. Frisina, Lois B. Travis, M. Eileen Dolan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tinnitus is a common sensorineural complication that can occur de novo or after cancer treatments involving cisplatin or radiotherapy. Considering the heterogeneous etiology and pathophysiology of tinnitus, the extent to which shared genetic
Externí odkaz:
https://doaj.org/article/288b8c672e924134bc31b6107b3bd81e
Autor:
Xindi Zhang, Matthew R. Trendowski, Emma Wilkinson, Mohammad Shahbazi, Paul C. Dinh, Megan M. Shuey, Regeneron Genetics Center, Darren R. Feldman, Robert J. Hamilton, David J. Vaughn, Chunkit Fung, Christian Kollmannsberger, Robert Huddart, Neil E. Martin, Victoria A. Sanchez, Robert D. Frisina, Lawrence H. Einhorn, Nancy J. Cox, Lois B. Travis, M. Eileen Dolan
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2801-2816 (2022)
Abstract Purpose Cisplatin is a critical component of first‐line chemotherapy for several cancers, but causes peripheral sensory neuropathy, hearing loss, and tinnitus. We aimed to identify comorbidities for cisplatin‐induced neurotoxicities amon
Externí odkaz:
https://doaj.org/article/44f25d0b9c9c44fea27f757e2ecf0dda
Autor:
Barthelemy Diouf, Claudia Wing, John C. Panetta, Donnie Eddins, Wenwei Lin, Wenjian Yang, Yiping Fan, Deqing Pei, Cheng Cheng, Shannon M. Delaney, Wei Zhang, Erik J. Bonten, Kristine R. Crews, Steven W. Paugh, Lie Li, Burgess B. Freeman 3rd, Robert J. Autry, Jordan A. Beard, Daniel C. Ferguson, Laura J. Janke, Kirsten K. Ness, Taosheng Chen, Stanislav S. Zakharenko, Sima Jeha, Ching‐Hon Pui, Mary V. Relling, M. Eileen Dolan, William E. Evans
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1490-1504 (2021)
Abstract Vincristine (VCR) is one of the most widely prescribed medications for treating solid tumors and acute lymphoblastic leukemia (ALL) in children and adults. However, its major dose‐limiting toxicity is peripheral neuropathy that can disrupt
Externí odkaz:
https://doaj.org/article/e3e40089bb0343279b5f3003e28e87aa
Autor:
Hai Lin, Katherine A. Hargreaves, Rudong Li, Jill L. Reiter, Yue Wang, Matthew Mort, David N. Cooper, Yaoqi Zhou, Chi Zhang, Michael T. Eadon, M. Eileen Dolan, Joseph Ipe, Todd C. Skaar, Yunlong Liu
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Single nucleotide variants (SNVs) in intronic regions have yet to be systematically investigated for their disease-causing potential. Using known pathogenic and neutral intronic SNVs (iSNVs) as training data, we develop the RegSNPs-intron al
Externí odkaz:
https://doaj.org/article/47cc29eb6f3b4c69825e0bce0b359331
Autor:
E. Bagnaschi, J. C. Costa, K. Sakurai, M. Borsato, O. Buchmueller, A. De Roeck, M. J. Dolan, J. R. Ellis, H. Flächer, K. Hahn, S. Heinemeyer, M. Lucio, D. Martínez Santos, K. A. Olive, S. Trifa, G. Weiglein
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 79, Iss 11, Pp 1-19 (2019)
Abstract We report the results of a global analysis of dark matter simplified models (DMSMs) with leptophobic mediator particles of spin one, considering the cases of both vector and axial-vector interactions with dark matter (DM) particles and quark
Externí odkaz:
https://doaj.org/article/0affe5b8a375450f9bc8a53ec734ec93
Autor:
E. Bagnaschi, K. Sakurai, M. Borsato, O. Buchmueller, M. Citron, J. C. Costa, A. De Roeck, M. J. Dolan, J. R. Ellis, H. Flächer, S. Heinemeyer, M. Lucio, D. Martínez Santos, K. A. Olive, A. Richards, V. C. Spanos, I. Suárez Fernández, G. Weiglein
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 78, Iss 3, Pp 1-38 (2018)
Abstract We use MasterCode to perform a frequentist analysis of the constraints on a phenomenological MSSM model with 11 parameters, the pMSSM11, including constraints from $$\sim 36$$ ∼36 /fb of LHC data at 13 TeV and PICO, XENON1T and PandaX-II s
Externí odkaz:
https://doaj.org/article/701f440222c442df8599bc6ebb34d91a
Autor:
J. C. Costa, E. Bagnaschi, K. Sakurai, M. Borsato, O. Buchmueller, M. Citron, A. De Roeck, M. J. Dolan, J. R. Ellis, H. Flächer, S. Heinemeyer, M. Lucio, D. Martínez Santos, K. A. Olive, A. Richards, G. Weiglein
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 78, Iss 2, Pp 1-22 (2018)
Abstract We describe a likelihood analysis using MasterCode of variants of the MSSM in which the soft supersymmetry-breaking parameters are assumed to have universal values at some scale $$M_\mathrm{in}$$ Min below the supersymmetric grand unificatio
Externí odkaz:
https://doaj.org/article/41f07c0ff34a472eae4334199afa3421
Autor:
Claudia Wing, Masaaki Komatsu, Shannon M. Delaney, Matthew Krause, Heather E. Wheeler, M. Eileen Dolan
Publikováno v:
Stem Cell Research, Vol 22, Iss C, Pp 79-88 (2017)
The generation of induced pluripotent stem cells (iPSCs) and differentiation to cells composing major organs has opened up the possibility for a new model system to study adverse toxicities associated with chemotherapy. Therefore, we used human iPSC-
Externí odkaz:
https://doaj.org/article/daa661df9d544a6c8d52dc468dd515d3
Autor:
E. Bagnaschi, M. Borsato, K. Sakurai, O. Buchmueller, R. Cavanaugh, V. Chobanova, M. Citron, J. C. Costa, A. De Roeck, M. J. Dolan, J. R. Ellis, H. Flächer, S. Heinemeyer, G. Isidori, M. Lucio, F. Luo, D. Martínez Santos, K. A. Olive, A. Richards, G. Weiglein
Publikováno v:
European Physical Journal C: Particles and Fields, Vol 77, Iss 4, Pp 1-28 (2017)
Abstract We perform a likelihood analysis of the minimal anomaly-mediated supersymmetry-breaking (mAMSB) model using constraints from cosmology and accelerator experiments. We find that either a wino-like or a Higgsino-like neutralino LSP, $$\tilde{\
Externí odkaz:
https://doaj.org/article/a792c676b365453f85a1eea16db564a1
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol 2008, Iss default, Pp 7-14 (2008)
Wei Zhang, R Stephanie Huang, M Eileen DolanSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637, USAAbstract: The goal of personalized medicine is to recommend drug treatment based on an individual’s
Externí odkaz:
https://doaj.org/article/5d7da38f70ce46f0ac959ab72d27709f