Zobrazeno 1 - 10
of 1 023
pro vyhledávání: '"M. Oza"'
Autor:
Rebecca S. Kristeleit, Yvette Drew, Amit M. Oza, Susan M. Domchek, Susana Banerjee, Rosalind M. Glasspool, Judith Balmaña, Lee-may Chen, Manish R. Patel, Howard A. Burris, Tamar Safra, Jennifer Borrow, Kevin K. Lin, Sandra Goble, Lara Maloney, Ronnie Shapira-Frommer
Publikováno v:
British Journal of Cancer. 128:255-265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ddbb016eb4cc600e10e751976a1515
https://doi.org/10.1038/s41416-022-02022-y
https://doi.org/10.1038/s41416-022-02022-y
Publikováno v:
Clinical Cancer Research. 29:305-308
Summary Efforts are under way to define the role of minimally invasive strategies for molecular monitoring and risk stratification in endometrial cancer. A recent publication aims to define the association between circulating tumor DNA level and dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a88c0cb6ac512090fe83ee163eb4e5
https://doi.org/10.1158/1078-0432.ccr-22-2781
https://doi.org/10.1158/1078-0432.ccr-22-2781
Autor:
Ainhoa Madariaga, Sandra A. Mitchell, Tyler Pittman, Lisa Wang, Valerie Bowering, Nisan Kavak, Judy Quintos, Karen Chang, Janelle Ramsahai, Katherine Karakasis, Stephen A. Welch, Neesha C. Dhani, Stephanie Lheureux, Amit M. Oza
Publikováno v:
Gynecologic Oncology. 167:226-233
A double-blind, randomized, placebo-controlled, phase 2 trial assessed gemcitabine in combination with the wee1 inhibitor adavosertib or placebo in platinum resistant or refractory high grade serous ovarian cancer (HGSOC), demonstrating improved prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e6824e1da9f694999dc7b2726b1967
https://doi.org/10.1016/j.ygyno.2022.08.006
https://doi.org/10.1016/j.ygyno.2022.08.006
Autor:
Rachel Campbell, Daniel S.J. Costa, Martin R. Stockler, Yeh Chen Lee, Jonathan A. Ledermann, Dominique Berton, Jalid Sehouli, Felicia T. Roncolato, Rachel O. Connell, Aikou Okamoto, Jane Bryce, Amit M. Oza, Elisabeth Avall-Lundqvist, Jonathan S. Berek, Anne Lanceley, Florence Joly, Felix Hilpert, Amanda Feeney, Marie C. Kaminsky, Katrina Diamante, Michael L. Friedlander, Madeleine T. King
Publikováno v:
Gynecologic Oncology. 166:254-262
The Measure of Ovarian Symptoms and Treatment (MOST) concerns is a validated patient-reported symptom assessment tool for assessing symptom benefit and adverse effects of palliative chemotherapy in women with recurrent ovarian cancer (ROC). We aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5807414259d2fdbf932232575215d830
https://doi.org/10.1016/j.ygyno.2022.05.024
https://doi.org/10.1016/j.ygyno.2022.05.024
Autor:
Eduardo Gonzalez-Ochoa, Amit M. Oza
Publikováno v:
Clinical Cancer Research.
Poly (ADP-ribose) polymerase (PARP) inhibitors exploit synthetic lethality in homologous recombination deficient (HDR) cells and are standard of care treatment in newly diagnosed and relapsed epithelial ovarian cancer (EOC). A recent article demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6b35708f53be2fdf2923a7a6adbe00
https://doi.org/10.1158/1078-0432.ccr-23-0652
https://doi.org/10.1158/1078-0432.ccr-23-0652
Autor:
Oliver Dorigo, Amit M. Oza, Tanja Pejovic, Prafull Ghatage, Sharad Ghamande, Diane Provencher, Lisa D. MacDonald, Heather Torrey, Valarmathy Kaliaperumal, Walead Ebrahimizadeh, Heather A. Hirsch, Yogesh Bramhecha, Jeannine Villella, Stephan Fiset
Publikováno v:
Clinical Cancer Research.
Purpose: Patients with platinum resistant ovarian cancer (OvCa) respond poorly to existing therapies. Hence there is a need for more effective treatments. Methods: The DeCidE1 trial is a multicenter, randomized, open-label, single-arm phase 2 study t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f582f518dde062370107ff4852b658
https://doi.org/10.1158/1078-0432.ccr-22-2595
https://doi.org/10.1158/1078-0432.ccr-22-2595
Autor:
Stephanie Lheureux, Anthony M. Joshua, Amit M. Oza, Bradly G. Wouters, Robert Rottapel, Marianne Koritzinsky, Valerie Bowering, Melania Pintilie, Wenjiang Zhang, Neesha C. Dhani, Sarbjot Gill, Eric X. Chen, Lisa Wang, Swati Garg, Xuan Li, Jeff P. Bruce, Michael Cabanero, Victoria Mandilaras, Ilaria Colombo, Troy Ketela, Zvi Shalev, Zhu Juan Li, Sree Narayanan Nair, Aleksandra Pesic, Ainhoa Madariaga, Stefano Marastoni
Supplementary Tables 1 and 2 show respectively the fold change of lysosomal function and size in treated sensitive/resistant cells obtained by mixed effect modelling. Supplementary Table 3 shows patients enrolled per dose-level (DL) and dose limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fd404fd6897678983cd02bc8e0d246
https://doi.org/10.1158/2767-9764.22544405
https://doi.org/10.1158/2767-9764.22544405
Autor:
Stephanie Lheureux, Anthony M. Joshua, Amit M. Oza, Bradly G. Wouters, Robert Rottapel, Marianne Koritzinsky, Valerie Bowering, Melania Pintilie, Wenjiang Zhang, Neesha C. Dhani, Sarbjot Gill, Eric X. Chen, Lisa Wang, Swati Garg, Xuan Li, Jeff P. Bruce, Michael Cabanero, Victoria Mandilaras, Ilaria Colombo, Troy Ketela, Zvi Shalev, Zhu Juan Li, Sree Narayanan Nair, Aleksandra Pesic, Ainhoa Madariaga, Stefano Marastoni
CRISPR screen TOV1946. Results of the Itra sensitizing CRISPR screen on the TOV1946 cell line using drugZ algorithm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804dd6533494157bd7a37534e70ba030
https://doi.org/10.1158/2767-9764.22544411.v1
https://doi.org/10.1158/2767-9764.22544411.v1
Autor:
Stephanie Lheureux, Anthony M. Joshua, Amit M. Oza, Bradly G. Wouters, Robert Rottapel, Marianne Koritzinsky, Valerie Bowering, Melania Pintilie, Wenjiang Zhang, Neesha C. Dhani, Sarbjot Gill, Eric X. Chen, Lisa Wang, Swati Garg, Xuan Li, Jeff P. Bruce, Michael Cabanero, Victoria Mandilaras, Ilaria Colombo, Troy Ketela, Zvi Shalev, Zhu Juan Li, Sree Narayanan Nair, Aleksandra Pesic, Ainhoa Madariaga, Stefano Marastoni
List of cell lines- Lentiviral constructs, lentivirus generation and infection- Apoptosis Assay- FILIPIN staining- Lysosomal assay and immunofluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7cec6d23c2991ff47759f744a9661b
https://doi.org/10.1158/2767-9764.22544408
https://doi.org/10.1158/2767-9764.22544408
Autor:
Stephanie Lheureux, Anthony M. Joshua, Amit M. Oza, Bradly G. Wouters, Robert Rottapel, Marianne Koritzinsky, Valerie Bowering, Melania Pintilie, Wenjiang Zhang, Neesha C. Dhani, Sarbjot Gill, Eric X. Chen, Lisa Wang, Swati Garg, Xuan Li, Jeff P. Bruce, Michael Cabanero, Victoria Mandilaras, Ilaria Colombo, Troy Ketela, Zvi Shalev, Zhu Juan Li, Sree Narayanan Nair, Aleksandra Pesic, Ainhoa Madariaga, Stefano Marastoni
CRISPR screen OVCAR5. Results of the Itra sensitizing CRISPR screen on the OVCAR5 cell line using drugZ algorithm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f4047cde9577fe058685762f58eb87
https://doi.org/10.1158/2767-9764.22544414
https://doi.org/10.1158/2767-9764.22544414