Zobrazeno 1 - 10
of 1 656
pro vyhledávání: '"M. Osame"'
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 10, Pp 2212-2218 (1996)
Lysosomal acid lipase (LAL) is a hydrolase essential for the intracellular degradation of cholesteryl esters and triglycerides. We previously reported a rat model of Wolman's disease (Wolman rat) that is deficient for LAL activity. In this study, we
Externí odkaz:
https://doaj.org/article/1ac8c8846fc74e8c9e828889d1348907
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 2, Pp 223-229 (1991)
We measured the cholestanol, cholesterol precursor (lathosterol), and plant sterol (campesterol and sitosterol) concentrations of serum and bile in 11 patients with cerebrotendinous xanthomatosis. The mean values of serum cholestanol, lathosterol, ca
Externí odkaz:
https://doaj.org/article/563f83c83ff143cfa7a60c0183317aff
Autor:
Tetsuhiko Taira, Ko-ichi Kawahara, M. Osame, Kimiyoshi Arimura, I. Maruyama, Ikkou Higashimoto, Hideo Mitsuyama, Wataru Matsuyama
Publikováno v:
Clinical and Experimental Immunology. 148:241-247
Summary Churg–Strauss syndrome (CSS) is a rare form of systemic vasculitis occurring in patients with asthma and hypereosinophilia; however, its mechanisms involved in the severe tissue inflammation with vasculitis are poorly understood. High mobil
Autor:
M. Osame, Kimiyoshi Arimura, Wataru Matsuyama, Yuko Shirahama, Ikkou Higashimoto, Mikiko Ono, Hideo Mitsuyama
Publikováno v:
Blood. 109:22-30
Churg-Strauss syndrome (CSS) is a systemic disease that shows marked eosinophilia along with eosinophil infiltration in the tissue. Prolonged eosinophil survival plays an important role in the pathogenesis of CSS; however, its detailed molecular mech
Autor:
Hideo Mitsuyama, Masaki Watanabe, Ikkou Higashimoto, M. Osame, Keiko Mizuno, Wataru Matsuyama, Kimiyoshi Arimura
Publikováno v:
Clinical and Experimental Immunology. 139:490-497
SummaryPulmonary tuberculosis, a granulomatous disease, has few serological markers for its activity. Recently, an increased plasma level of stromal derived factor 1 alpha (SDF-1α), which can induce strong chemotaxis of cells through its receptor CX
Publikováno v:
Neurological Sciences. 24:357-360
A 54-year-old man developed left hemiparesis and tactile and deep sensory disturbance following onset of rightside cervical pain. These symptoms resulted from an isolated infarct in the right medial area of the upper medulla oblongata and intracrania
Publikováno v:
Clinical and Experimental Immunology. 133:397-403
SUMMARYHuman T lymphotrophic virus type-I (HTLV-I), a human retrovirus, infects CD4+ lymphocytes and is thought to modify their function; a possible association with pulmonary diseases has also been suggested. However, little is known about the influ
Publikováno v:
Acta Neurologica Scandinavica. 106:104-108
Objective – To clarify the relationship between mitochondrial DNA (mtDNA) sequence variations and phenotypes in patients with A3243G mutation. Materials and methods – We studied whole mtDNA sequences in two families with A3243G mutation and chara
Autor:
S. Izumo, K. Usuku, M. Osame, Minoru Nakamura, Toshinobu Fujiyoshi, Yoshihisa Yamano, Bernd Kitze, Shunro Sonoda, Shinji Yashiki
Publikováno v:
Clinical and Experimental Immunology. 111:278-285
SUMMARYHTLV-1 causes two distinct human diseases, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T cell leukaemia/lymphoma (ATL). Persistently infected individuals carry a risk of
Publikováno v:
Lupus. 6:590-596
We developed a novel assay using human thrombomodulin (TM), which detected overall abnormalities in the protein C anticoagulant pathway (PC pathway). This assay indicates the degree of inhibition of prothrombinase by TM, which is represented as the p