Zobrazeno 1 - 10
of 1 083
pro vyhledávání: '"M. Orre"'
Autor:
Nona Struyf, Albin Österroos, Mattias Vesterlund, Cornelia Arnroth, Tojo James, Stephanie Sunandar, Georgios Mermelekas, Anna Bohlin, Kerstin Hamberg Levedahl, Sofia Bengtzén, Rozbeh Jafari, Lukas M. Orre, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi, Brinton Seashore-Ludlow, Tom Erkers
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Consistent handling of samples is crucial for achieving reproducible molecular and functional testing results in translational research. Here, we used 229 acute myeloid leukemia (AML) patient samples to assess the impact of sample handling o
Externí odkaz:
https://doaj.org/article/b137e1c0bbc24a2a9826fbbf5bd104d4
Autor:
Quang Thinh Trac, Yudi Pawitan, Tian Mou, Tom Erkers, Päivi Östling, Anna Bohlin, Albin Österroos, Mattias Vesterlund, Rozbeh Jafari, Ioannis Siavelis, Helena Bäckvall, Santeri Kiviluoto, Lukas M. Orre, Mattias Rantalainen, Janne Lehtiö, Sören Lehmann, Olli Kallioniemi, Trung Nghia Vu
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Despite some encouraging successes, predicting the therapy response of acute myeloid leukemia (AML) patients remains highly challenging due to tumor heterogeneity. Here we aim to develop and validate MDREAM, a robust ensemble-based predictio
Externí odkaz:
https://doaj.org/article/708587f7449c4c56ba44998f3046d58f
Autor:
Rosanne E. Veerman, Loes Teeuwen, Paulo Czarnewski, Gözde Güclüler Akpinar, AnnSofi Sandberg, Xiaofang Cao, Maria Pernemalm, Lukas M. Orre, Susanne Gabrielsson, Maria Eldh
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers, but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities, a combination of methods is needed. However, this
Externí odkaz:
https://doaj.org/article/288f51556f364ffeab621ae94079f212
Autor:
Henrik J. Johansson, Fabio Socciarelli, Nathaniel M. Vacanti, Mads H. Haugen, Yafeng Zhu, Ioannis Siavelis, Alejandro Fernandez-Woodbridge, Miriam R. Aure, Bengt Sennblad, Mattias Vesterlund, Rui M. Branca, Lukas M. Orre, Mikael Huss, Erik Fredlund, Elsa Beraki, Øystein Garred, Jorrit Boekel, Torill Sauer, Wei Zhao, Silje Nord, Elen K. Höglander, Daniel C. Jans, Hjalmar Brismar, Tonje H. Haukaas, Tone F. Bathen, Ellen Schlichting, Bjørn Naume, Consortia Oslo Breast Cancer Research Consortium (OSBREAC), Torben Luders, Elin Borgen, Vessela N. Kristensen, Hege G. Russnes, Ole Christian Lingjærde, Gordon B. Mills, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Janne Lehtiö
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Gene expression profiles can classify breast cancer into five clinically relevant subtypes. Here, the authors perform an in-depth quantitative profiling of the proteome of 45 breast tumors, and show they can recapitulate the transcriptome-based class
Externí odkaz:
https://doaj.org/article/6d38d3e496e94ae593fe7bedce5833e0
Autor:
Yafeng Zhu, Lukas M. Orre, Henrik J. Johansson, Mikael Huss, Jorrit Boekel, Mattias Vesterlund, Alejandro Fernandez-Woodbridge, Rui M. M. Branca, Janne Lehtiö
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Proteogenomics enables the discovery of protein coding regions and disease-relevant mutations but their verification remains challenging. Here, the authors combine peptide discovery, curation and validation in an integrated proteogenomics workflow, r
Externí odkaz:
https://doaj.org/article/44312d94faad4197b162f991fca661ad
Autor:
Anja Reithmeier, Elena Panizza, Michael Krumpel, Lukas M. Orre, Rui M. M. Branca, Janne Lehtiö, Barbro Ek-Rylander, Göran Andersson
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-19 (2017)
Abstract Background Tartrate-resistant acid phosphatase (TRAP/ACP5), a metalloenzyme that is characteristic for its expression in activated osteoclasts and in macrophages, has recently gained considerable focus as a driver of metastasis and was assoc
Externí odkaz:
https://doaj.org/article/1423ed8cf89a49e98b7142533816f612
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Protein phosphorylation is involved in the regulation of most eukaryotic cells functions and mass spectrometry-based analysis has made major contributions to our understanding of this regulation. However, low abundance of phosphorylated spec
Externí odkaz:
https://doaj.org/article/490425e62f0e446b872c186b12ec9123
Publikováno v:
Cancer/Radiothérapie. 26:938-940
Autor:
Taner Arslan, Yanbo Pan, Georgios Mermelekas, Mattias Vesterlund, Lukas M. Orre, Janne Lehtiö
Publikováno v:
Nature Protocols. 17:1832-1867
The molecular functions of a protein are defined by its inherent properties in relation to its environment and interaction network. Within a cell, this environment and network are defined by the subcellular location of the protein. Consequently, it i
Publikováno v:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 26(6-7)
Cybersecurity is a major issue in today's world. Health structures are not immune to attacks aimed at stealing valuable sensitive data, demanding a ransom, disrupting or paralyzing a system for political purposes. The Dax Hospital Center (France) had