Výsledky vyhledávání - "M. O. Staskawicz"

Cytotoxicity against human peripheral blood mononuclear cells and T cell lines mediated by anti-T cell immunotoxins in the absence of added potentiator

Autor: H.-M. Wu, D. M. Fishwild, M. O. Staskawicz, S. F. Carroll

Publikováno v: Clinical and Experimental Immunology. 86:506-513

SUMMARY Several in vitro assays have indicated that anti-T cell immunotoxins (IT), composed of monoclonal antibodies (MoAbs)conjugated to ricin A chain (RTA), are maximally effective against T cells only in the presence of potentiators. It was though

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510edbf6431ce3c1eef9998dd18022d6
https://doi.org/10.1111/j.1365-2249.1991.tb02961.x

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Suppressor cells: dependence on assay conditions for functional activity

Autor: D D Eardley, M O Staskawicz, R K Gershon

Publikováno v: The Journal of Experimental Medicine

Spleen cells educated in vitro with sheep red blood cells (SRBC) suppressed the plaque-forming cell response of Mishell-Dutton assay cultures challenged with optimal doses of SRBC. Changing conditions in the assay cultures changed the effect educated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cb55f752a38800b39644a938281767
https://doi.org/10.1084/jem.143.5.1211

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Immune responsiveness of adult mice exposed neonatally to diethylstilbestrol, steroid hormones, or vitamin A

Autor: S C, Ways, P B, Blair, H A, Bern, M O, Staskawicz

Publikováno v: Journal of environmental pathology and toxicology. 3(5-6)

Neonatal hormone treatments with estradiol, progesterone, testosterone, cortisol, or especially diethylstilbestrol (DES) were found to alter the immune responsiveness of spleen cells from female mice. No significant change in immunocompetence occurre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfd10604dff6e6d5bd17a0d83a543378
https://pubmed.ncbi.nlm.nih.gov/7441080

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Inhibitor cells in spleens of mice with low natural killer activity

Autor: P B, Blair, M O, Staskawicz, J S, Sam

Publikováno v: Journal of the National Cancer Institute. 71(3)

Inbred strains of mice differ markedly in levels of natural killer (NK) cytotoxic activity. BPS mice normally have very low spleen cell NK activity. However, their NK activity can be significantly augmented with the use of interferon inducer, which s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd8aff364822094ea5bc57c54b3ba069
https://pubmed.ncbi.nlm.nih.gov/6577231

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