Zobrazeno 1 - 10
of 88
pro vyhledávání: '"M. Niven"'
Autor:
Trilok Neupane, Lydia R. Chambers, Alexander J. Godfrey, Melina M. Monlux, Evan J. Jacobs, Sophia Whitworth, Jamie E. Spawn, Seo Hee K. Clingman, Kathleen L. Vergunst, Fair M. Niven, James J. Townley, Iris W. Orion, Carly R. Goodspeed, Kathryn A. Cooper, Jeff D. Cronk, Jennifer N. Shepherd, David N. Langelaan
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-13 (2022)
The RquA protein is required for rhodoquinone biosynthesis; however, its exact function is not yet known. Here, the authors demonstrate that RquA is homologous to SAM-dependent methyltransferases but functions as an aminotransferase using Mn2+ as cof
Externí odkaz:
https://doaj.org/article/b2e554daf1fb49c2b8306775749eb555
Autor:
Catherine E. Hanratty, John G. Matthews, Joseph R. Arron, David F. Choy, Ian D. Pavord, P. Bradding, Christopher E. Brightling, Rekha Chaudhuri, Douglas C. Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J. Fowler, Tim C. Hardman, Tim Harrison, Cécile T. Holweg, Peter H. Howarth, James Lordan, Adel H. Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M. Niven, Douglas S. Robinson, Dominick E. Shaw, Samantha Walker, Ashley Woodcock, Liam G. Heaney, on behalf of the RASP-UK (Refractory Asthma Stratification Programme) Consortium
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients
Externí odkaz:
https://doaj.org/article/8b2b5c94718a45699e6b6b269b64f460
Publikováno v:
BMJ Open, Vol 9, Iss 6 (2019)
Externí odkaz:
https://doaj.org/article/1fb6a39c16eb46f6be3f516a8f90e12c
Akademický článek
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Akademický článek
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Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 8 (2015)
Irritable bowel syndrome (IBS) is notoriously difficult to treat and this situation is unlikely to change until the pathophysiology is better understood. There is no doubt that IBS is a multifactorial condition but it is likely that the relative cont
Externí odkaz:
https://doaj.org/article/b9c5b02d40af4140b04c473b4965abcd
Autor:
Chris Newby, Liam G Heaney, Andrew Menzies-Gow, Rob M Niven, Adel Mansur, Christine Bucknall, Rekha Chaudhuri, John Thompson, Paul Burton, Chris Brightling, British Thoracic Society Severe Refractory Asthma Network
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102987 (2014)
Severe refractory asthma is a heterogeneous disease. We sought to determine statistical clusters from the British Thoracic Society Severe refractory Asthma Registry and to examine cluster-specific outcomes and stability.Factor analysis and statistica
Externí odkaz:
https://doaj.org/article/70c674ec43c8481fa98f40da71e7d52f
Publikováno v:
Cytotherapy. 22:S55-S56
Background & Aim Vascular diseases in which the blood supply is blocked are the main cause of death and disability globally with more people dying annually from CVD than any other disease. These diseases in people with diabetes and the elderly affect
Akademický článek
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Autor:
Ian D, Pavord, Neil C, Thomson, Robert M, Niven, Paul A, Corris, Kian Fan, Chung, Gerard, Cox, Brian, Armstrong, Narinder S, Shargill, Michel, Laviolette, Arthur S, Slutsky
Publikováno v:
Annals of Allergy, Asthma & Immunology. 111:402-407
Background: Patients with severe refractory asthma treated with bronchial thermoplasty (BT), a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle, were followed up for 5 years to evaluate long-term safety of