Zobrazeno 1 - 10
of 1 480
pro vyhledávání: '"M. Nissan"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract In the current study, we designed and synthesized a series of new quinoline derivatives 10a-p as antiproliferative agents targeting cancer through inhibition of VEGFR-2. Preliminary molecular docking to assess the interactions of the designe
Externí odkaz:
https://doaj.org/article/fa84e6d1b71d42208b3a605f3cb0e6d6
Publikováno v:
International Journal of Dentistry, Vol 2024 (2024)
Background. Understanding the correlation between temporomandibular joint disorder (TMD) parameters and various occlusal features can play a significant role in diagnosing and treating occlusal problems and their potential consequences on TMD. Object
Externí odkaz:
https://doaj.org/article/ae0aea03ccca4438a91e75d50374b72a
Autor:
Mostafa M. Ghorab, Mansour S. Alsaid, Mohamed S. A. El-Gaby, Mahmoud M. Elaasser, Yassin M. Nissan
Publikováno v:
Chemistry Central Journal, Vol 11, Iss 1, Pp 1-14 (2017)
Abstract Background Various thiourea derivatives have been used as starting materials for compounds with better biological activities. Molecular modeling tools are used to explore their mechanism of action. Results A new series of thioureas were synt
Externí odkaz:
https://doaj.org/article/1937e12809ab459fa143cd227757e66d
Publikováno v:
Virology. 570:18-28
The challenge continues globally triggered by the absence of an approved antiviral drug against COVID-19 virus infection necessitating global concerted efforts of scientists. Nature still provides a renewable source for drugs used to solve many healt
Autor:
Aliya M. S. El Newahie, Yassin M. Nissan, Nasser S. M. Ismail, Dalal A. Abou El Ella, Sohair M. Khojah, Khaled A.M. Abouzid
Publikováno v:
Molecules, Vol 24, Iss 6, p 1175 (2019)
The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 human colon carcinoma, He
Externí odkaz:
https://doaj.org/article/57a8f786f960428fa7e2ea32e0f87e0f
Autor:
Gehad A. Abdel Jaleel, Ahmed Abbass Mohamed Abd El-Rahman Selim, Enas Ibrahim Mohammed, Yassin M. Nissan, Fatma A. Ragab
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:742-752
Five new series of hydroxybenzofuranyl-pyrazolyl chalcones 3a,b, hydroxyphenyl-pyrazolyl chalcones 6a-c and their corresponding pyrazolylpyrazolines 4a, d, 7a-c and 8a-f have been synthesized and evaluated for their in vitro cyclooxygenase (COX)-1 an
Autor:
Samar H. Fahim, Mohammad Alaraby Salem, Yassin M. Nissan, Amal A.M. Eissa, Mona A. Gamal, Fatma A. Ragab
Publikováno v:
Archiv der Pharmazie.
New coumarin derivatives 9a-f, 10a-e, and 11a-f were synthesized and evaluated for their cytotoxic activity against a human breast cancer cell line (MCF-7). All compounds exhibited good activity in the nanomolar range, using doxorubicin and erlotinib
Autor:
M. Alaraby Salem, Mamdouh Moawad Ali, Fatma A. Ragab, Yassin M. Nissan, Ahmed Abbass Mohamed Abd El-Rahman Selim
Publikováno v:
Natural product research. 36(10)
Novel pyrazolyl 2-hydroxychalcone derivatives 3a–e and pyrazolylpyrazoline derivatives 4a–e and 5a–j derived from the naturally existing furochromone (Khellin) were synthesized and evaluated for th...
Publikováno v:
Virology
The COVID-19 pandemic has urged for the repurposing of existing drugs for rapid management and treatment. Renin inhibitors down regulation of ACE2, which is an essential receptor for SARS-CoV-2 infection that is responsible for COVID-19, in addition
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