Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M. Nieboer"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Over the past years, large consortia have been established to fuel the sequencing of whole genomes of many cancer patients. Despite the increased abundance in tools to study the impact of SNVs, non-coding SVs have been largely ignored in the
Externí odkaz:
https://doaj.org/article/0b53ef2e3f784aba84c29c9f9d64c804
Autor:
Mircea Cretu Stancu, Markus J. van Roosmalen, Ivo Renkens, Marleen M. Nieboer, Sjors Middelkamp, Joep de Ligt, Giulia Pregno, Daniela Giachino, Giorgia Mandrile, Jose Espejo Valle-Inclan, Jerome Korzelius, Ewart de Bruijn, Edwin Cuppen, Michael E. Talkowski, Tobias Marschall, Jeroen de Ridder, Wigard P. Kloosterman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The detection of structural variants can be difficult with short-read sequencing technology, especially when variants are highly complex. Here, the authors use a MinION nanopore sequencer to analyse two patient genomes and develop NanoSV to map known
Externí odkaz:
https://doaj.org/article/2f2f3bf4470440ca92bbf204569b91fc
Autor:
Michelle L M Mulder, Johanna E Vriezekolk, Tamara W van Hal, Lieke M Nieboer, Nathan den Broeder, Elke M G J de Jong, Alfons A den Broeder, Frank H J van den Hoogen, Philip S Helliwell, Mark H Wenink
Publikováno v:
The Lancet. Rheumatology, 4, 4, pp. E252-E261
The Lancet. Rheumatology, 4, E252-E261
The Lancet. Rheumatology, 4, E252-E261
Item does not contain fulltext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3afac53f74d3ed7c502c39c909c5e1
https://doi.org/10.1016/s2665-9913(22)00028-5
https://doi.org/10.1016/s2665-9913(22)00028-5
Autor:
Marleen M Nieboer, Lambert C J Dorssers, Roy Straver, Leendert H J Looijenga, Jeroen de Ridder
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208002 (2018)
Most tumors are composed of a heterogeneous population of subclones. A more detailed insight into the subclonal evolution of these tumors can be helpful to study progression and treatment response. Problematically, tumor samples are typically very he
Externí odkaz:
https://doaj.org/article/da7834b4e2bd4dccb0195e35ca53e025
Akademický článek
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Autor:
Ronald van Marion, Lambert C. J. Dorssers, Job van Riet, Ad J. M. Gillis, Hans Stoop, Marleen M. Nieboer, Leendert H. J. Looijenga, Harmen J.G. van de Werken, J. Wolter Oosterhuis, Jeroen de Ridder
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 120(4), 444-452. Nature Publishing Group
British Journal of Cancer, 120(4), 444-452. Nature Publishing Group
BackgroundTesticular germ cell cancer (TGCC), being the most frequent malignancy in young Caucasian males, is initiated from an embryonic germ cell. This study determines intratumor heterogeneity to unravel tumor progression from initiation till meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22a4587d16f9d834e6af89160b21a0e
https://doi.org/10.1038/s41416-019-0381-1
https://doi.org/10.1038/s41416-019-0381-1
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Over the past years, large consortia have been established to fuel the sequencing of whole genomes of many cancer patients. Despite the increased abundance in tools to study the impact of SNVs, non-coding SVs have been largely ignored in these data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3135379708e51d1929995a139fdaee
http://europepmc.org/articles/PMC8277903
http://europepmc.org/articles/PMC8277903
Autor:
Jeroen de Ridder, Marleen M. Nieboer
Publikováno v:
Bioinformatics (Oxford, England). 36(Suppl_2)
Motivation Despite the fact that structural variants (SVs) play an important role in cancer, methods to predict their effect, especially for SVs in non-coding regions, are lacking, leaving them often overlooked in the clinic. Non-coding SVs may disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f611c5d4277d234bc54b124e7fcc8deb
https://pubmed.ncbi.nlm.nih.gov/33381833
https://pubmed.ncbi.nlm.nih.gov/33381833
Akademický článek
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Akademický článek
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