Zobrazeno 1 - 10
of 108
pro vyhledávání: '"M. Nawara"'
Autor:
Seyedeh Fatemeh Razavipour, Hyunho Yoon, Kibeom Jang, Minsoon Kim, Hend M. Nawara, Amir Bagheri, Wei-Chi Huang, Miyoung Shin, Dekuang Zhao, Zhiqun Zhou, Derek Van Boven, Karoline Briegel, Lluis Morey, Tan A. Ince, Michael Johnson, Joyce M. Slingerland
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In many cancers, a stem-like cell subpopulation mediates tumor initiation, dissemination and drug resistance. Here, we report that cancer stem cell (CSC) abundance is transcriptionally regulated by C-terminally phosphorylated p27 (p27pT157pT
Externí odkaz:
https://doaj.org/article/7bf3e62bafb2439da609657ec68e47b4
Autor:
Kazuki Kumon, Said M. Afify, Ghmkin Hassan, Shunsuke Ueno, Sadia Monzur, Hend M. Nawara, Hagar A. Abu Quora, Mona Sheta, Yanning Xu, Xiaoying Fu, Maram H. Zahra, Akimasa Seno, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cancer stem cells (CSCs) are subpopulations in the malignant tumors that show self-renewal and multilineage differentiation into tumor microenvironment components that drive tumor growth and heterogeneity. In previous studies, our group succ
Externí odkaz:
https://doaj.org/article/94748b8e5a1d4c658dc75ade67ea7e3d
Autor:
Hager Mansour, Ph.D., Said M. Afify, Ph.D., Ghmkin Hassan, Ph.D., Hagar A. Abu Quora, Ph.D., Hend M. Nawara, Ph.D., Maram H. Zahra, Ph.D., Juan Du, Ph.D., Sadia Monzur, Ph.D., Toshiaki Ohara, M.D., Ph.D., Akimasa Seno, PhD, Masaharu Seno, Ph.D.
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 5, Iss , Pp 100062- (2022)
Metastasis is one of the major causes of cancer deaths. However, the mechanisms of cancer cells acquiring aggressiveness and metastatic potential are still under investigation. Although cancer stem cells (CSCs) have been suggested as tumor initiating
Externí odkaz:
https://doaj.org/article/ee1fe0fc410d44f9a94966074602ca1c
Autor:
Ghmkin Hassan, Said M. Afify, Maram H. Zahra, Hend M. Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S. Salomon, Akimasa Seno, Masaharu Seno
Publikováno v:
Cytotechnology. 75:243-253
Induced pluripotent stem cells (iPSCs) are useful tools for modeling diseases and developing personalized medicine. We have been developing cancer stem cells (CSCs) from iPSCs with conditioned medium (CM) of cancer-derived cells as the mimicry of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff36a9153d9a8c660271ca46a223204
https://doi.org/10.1007/s10616-023-00575-1
https://doi.org/10.1007/s10616-023-00575-1
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 500 (2021)
Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism that disrupts the dynamics of microtubules and induces mitotic arrest and
Externí odkaz:
https://doaj.org/article/904619f709ce416c99780c7a258f5689
Autor:
Said M, Afify, Ghmkin, Hassan, Hiroko, Ishii, Sadia, Monzur, Hend M, Nawara, Amira, Osman, Hagar A, Abu Quora, Mona, Sheta, Maram H, Zahra, Akimasa, Seno, Masaharu, Seno
Publikováno v:
Advances in experimental medicine and biology. 1393
Cancer stem cells (CSCs) are small subpopulation sharing similar properties like normal stem such as self-renewal and differentiation potential to direct tumor growth. Last few years, scientists considered CSCs as the cause of phenotypic heterogeneit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f72397fc4748de2b83ea16bd2e8e48c0
https://pubmed.ncbi.nlm.nih.gov/36587303
https://pubmed.ncbi.nlm.nih.gov/36587303
Publikováno v:
Advances in experimental medicine and biology. 1393
Many tumors are resistant to conventional cancer therapies because a tumor is composed of heterogeneous cell population. Especially, subpopulation of cancer stem cells, which have self-renewal and differentiation properties and responsible for the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d3fa3660b0b5abdc1e3cf542bef6bb
https://pubmed.ncbi.nlm.nih.gov/36587305
https://pubmed.ncbi.nlm.nih.gov/36587305
Autor:
Sadia Monzur, Masaharu Seno, Hend M. Nawara, Akimasa Seno, Juan Du, Maram H. Zahra, Hagar A. Abu Quora, Ghmkin Hassan, Said M. Afify, Ryo Uesaki, Hager Mansour, Mona Sheta, Samah El-Ghlban
Publikováno v:
Biochemical and Biophysical Research Communications. 583:49-55
Cancer stem cells (CSCs) are responsible for cancer initiation, drug resistance, and aggressive tumor phenotypes. Our lab has established a novel method to induce CSCs from induced pluripotent stem (iPS) cells in a microenvironment mimicking chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f11aa20eaf3d33b4d1dbc5ef8e4269
https://doi.org/10.1016/j.bbrc.2021.10.047
https://doi.org/10.1016/j.bbrc.2021.10.047
Publikováno v:
Zagazig University Medical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81059b4860705ced17b1cfb90a6b925e
https://doi.org/10.21608/zumj.2022.171129.2668
https://doi.org/10.21608/zumj.2022.171129.2668
Autor:
Ibrahim M. Salem, Abdallah M. Nawara, Mohamed M. Awadalla, Tarek A. Ghonemy, Mohamed A. Zanaty, Maher B. Borai, Mohamed I. Salem, Niveen S. Sakla
Background Cardiovascular disease is considered a common cause of morbidity and mortality in patients with end-stage renal disease on hemodialysis. Elevated levels of glycated hemoglobin (HbA1c) are associated with CVD in diabetic patients. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4f085af9dabe0b3a61a2b3c1c54dba
https://doi.org/10.21203/rs.3.rs-2184530/v1
https://doi.org/10.21203/rs.3.rs-2184530/v1
