Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M. N. Weitzmann"'
Autor:
Jeffrey L. Lennox, Kehmia Titanji, Neeta Shenvi, M. N. Weitzmann, Aswani Vunnava, Ighovwhera Ofotokun, Kirk A. Easley, Andrea Knezevic, Antonina Foster, Anandi N. Sheth
Publikováno v:
AIDS. 32:885-894
OBJECTIVE Higher incidence of osteopenia and osteoporosis underlie increased rates of fragility fracture in HIV infection. B cells are a major source of osteoprotegerin (OPG), an inhibitor of the key osteoclastogenic cytokine receptor activator of nu
Publikováno v:
The Open bone journal
Aging is a risk factor for osteoclastic bone loss and bone fracture. Receptor activator of NF-κB ligand (RANKL) is the key effector cytokine for osteoclastogenesis and bone resorption, and is moderated by its decoy receptor osteoprotegerin (OPG). Th
Publikováno v:
Europe PubMed Central
In unstimulated conditions osteoclast renewal occurs as a result of the stromal cell production of the key osteoclastogenic factors, receptor activator of NFkB ligand (RANKL) and macrophage colony-stimulating factor (M-CSF). Inflammation is known to
Autor:
R B Kimble, Sunil Srivastava, Roberto Pacifici, Jeffrey Milbrandt, M Zahner, M N Weitzmann, F. P. Ross, M Rizzo
Publikováno v:
Journal of Clinical Investigation. 102:1850-1859
Central to the pathogenesis of osteoporosis is the ability of estrogen deficiency to increase osteoclast formation by enhancing stromal cell production of the osteoclastogenic cytokine macrophage colony-stimulating factor (M-CSF). We report that stro
Autor:
M. N. Weitzmann, Masayoshi Yamaguchi
Publikováno v:
Molecular Medicine Reports. 2
The carotene p-hydroxycinnamic acid and the xanthophyll β-cryptoxanthin are members of the carotenoid family of plant-derived pigments, which are endowed with anti-osteoporotic properties in vivo. p-Hydroxycinnamic acid and β-cryptoxanthin have bee
Autor:
Mark S. Nanes, Jill A. Rahnert, Janet Rubin, M. N. Weitzmann, Francesco Grassi, Roberto Pacifici, Xian Fan
Publikováno v:
Endocrinology. 147(9)
Nitric oxide is a ubiquitous estrogen-regulated signaling molecule that has been implicated in the regulation of bone maturation and remodeling. To better understand the role that bone-cell-secreted nitric oxide plays in ovariectomy-induced modificat
Publikováno v:
Journal of cellular biochemistry. 78(2)
The role of B lymphocytes in osteoclast (OC) formation is controversial, because both stimulatory and inhibitory effects of B-lineage cells on osteoclastogenesis and life span have been reported. In this study, we have investigated the effects of mat