Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. N. Needle"'
Autor:
P G, Fisher, M N, Needle, A, Cnaan, H, Zhao, J R, Geyer, P T, Molloy, J W, Goldwein, A B, Herman-Liu, P C, Phillips
Publikováno v:
Cancer. 83(3)
A trend toward the use of prolonged postoperative chemotherapy, with radiotherapy deferred until relapse, has emerged for very young children with malignant brain tumors. This study was undertaken to determine the failure patterns among infants who r
Autor:
S M, Blaney, M N, Needle, A, Gillespie, J K, Sato, G H, Reaman, S L, Berg, P C, Adamson, M D, Krailo, W A, Bleyer, D G, Poplack, F M, Balis
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(2)
The antitumor activity of topotecan administered as a 72-h continuous i.v. infusion was evaluated in children with refractory neuroblastoma and sarcomas of soft tissue and bone. We also attempted to increase the dose intensity of topotecan by includi
Autor:
H, Bertsch, S, Rudoler, M N, Needle, P, Malloy, L, Sutton, J, Belasco, A, Meadows, J, Goldwein
Publikováno v:
Medical and pediatric oncology. 30(2)
We reviewed all pediatric cases referred for emergent/urgent therapy (requiring treatment within 48 hours) to identify frequency, patterns of presentation, and efficacy of therapy. We defined five categories of emergent/urgent therapy based on irradi
Autor:
M N, Needle, P T, Molloy, J R, Geyer, A, Herman-Liu, J B, Belasco, J W, Goldwein, L, Sutton, P C, Phillips
Publikováno v:
Medical and pediatric oncology. 29(1)
Pre-clinical data and adult experience suggests that topoisomerase targeted anti-cancer agents may be highly schedule dependent, and efficacy may improve with prolonged exposure. To investigate this hypothesis, 28 children with recurrent brain and so
Publikováno v:
Medical and pediatric oncology. 29(1)
Autor:
R J, Packer, M, Prados, P, Phillips, H S, Nicholson, J M, Boyett, J, Goldwein, L B, Rorke, M N, Needle, L, Sutton, R A, Zimmerman, C R, Fitz, L G, Vezina, E, Etcubanas, J C, Wallenberg, G, Reaman, W, Wara
Publikováno v:
Cancer. 77(10)
Prognosis for the majority of children with brain stem gliomas is dismal. In previous studies, recombinant beta-interferon (r beta IF) has been shown to be effective for children with recurrent brain stem gliomas and may also act synergistically with
Publikováno v:
Journal of Clinical Oncology. 23:4604-4604
4604 Background: Immunomodulatory drugs are compounds that originated via the deliberate structural modification of thalidomide. CC-5013 a derivative with enhanced immunological and anti-angiogenic...
Autor:
Robert J. Mayer, E. Van Cutsem, Philip J. Stella, Philip J. Gold, H. J. Lenz, Allen Lee Cohn, N. Azarnia, B. Mirtsching, Andrew William Pippas, M. N. Needle
Publikováno v:
Journal of Clinical Oncology. 22:3510-3510
3510 Background: Cetuximab (Erbitux) has demonstrated activity in patients with epidermal growth factor receptor (EGFR) expressing colorectal cancer (CRC) refractory to irinotecan (CPT-11) both as a single agent and in combination with irinotecan. Th