Výsledky vyhledávání

'A system biology' approach to bioinformatics and functional genomics in complex human diseases: arthritis

Autor: M G, Attur, M N, Dave, K, Tsunoyama, M, Akamatsu, M, Kobori, J, Miki, S B, Abramson, M, Katoh, A R, Amin

Publikováno v: Current issues in molecular biology. 4(4)

Human and other annotated genome sequences have facilitated generation of vast amounts of correlative data, from human/animal genetics, normal and disease-affected tissues from complex diseases such as arthritis using gene/protein chips and SNP analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbb8c90aada41480e91582575626eb79
https://pubmed.ncbi.nlm.nih.gov/12432964

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Osteopontin: an intrinsic inhibitor of inflammation in cartilage

Autor: M G, Attur, M N, Dave, S, Stuchin, A J, Kowalski, G, Steiner, S B, Abramson, D T, Denhardt, A R, Amin

Publikováno v: Arthritis and rheumatism. 44(3)

To identify extracellular and intraarticular matrix components that are differentially expressed in normal and osteoarthritis (OA)-affected cartilage and to investigate their functions with respect to regulation of mediators of inflammation.Different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57d4014c72587d09474bafabc1c62e1f
https://pubmed.ncbi.nlm.nih.gov/11263772

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A novel mechanism of action of chemically modified tetracyclines: inhibition of COX-2-mediated prostaglandin E2 production

Autor: R N, Patel, M G, Attur, M N, Dave, I V, Patel, S A, Stuchin, S B, Abramson, A R, Amin

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(6)

Tetracyclines (doxycycline and minocycline) inhibit inducible NO synthase expression and augment cyclooxygenase (COX)-2 expression and PGE2 production. In contrast, chemically modified tetracyclines (CMTs), such as CMT-3 and -8 (but not CMT-1, -2, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85578d89db69598f2e6d1d8467e62951
https://pubmed.ncbi.nlm.nih.gov/10477618

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A counter-selectable marker for genetic transformation of the yeast Schwanniomyces alluvius

Autor: M. N. Dave, Bharat B. Chattoo

Publikováno v: Applied microbiology and biotechnology. 48(2)

We report here a counter-selectable marker system for genetic transformation of the yeast Schwanniomyces alluvius, based on the complementation of uracil auxotrophs defective in either orotidine-5'-phosphate decarboxylase (URA3) or orotidine-5'-pyrop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6732e78fe4e4662fcef851a849c34a
https://pubmed.ncbi.nlm.nih.gov/9299778

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