Zobrazeno 1 - 10
of 262
pro vyhledávání: '"M. Mishler"'
Autor:
Noor Radde, Genevieve A. Mortensen, Diya Bhat, Shireen Shah, Joseph J. Clements, Sean P. Leonard, Matthew J. McGuffie, Dennis M. Mishler, Jeffrey E. Barrick
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Engineered DNA will slow the growth of a host cell if it redirects limiting resources or otherwise interferes with homeostasis. Escape mutants that alleviate this burden can rapidly evolve and take over cell populations, making genetic engin
Externí odkaz:
https://doaj.org/article/d2a482698d444693acde04b2a15a0850
Autor:
John D. Palmer, Douglas W. Huestis
Publikováno v:
Transfusion. 24:140-140
Publikováno v:
Journal of Microbiology & Biology Education, Vol 19, Iss 2 (2018)
Lack of access to reagents and equipment can make performing microbiology experiments difficult in K-12 classrooms and do-it-yourself (DIY) science settings. We demonstrate how the bacterium Sphingomonas paucimobilis can be used to synthesize gellan
Externí odkaz:
https://doaj.org/article/3145de69c90548b281dd5a403ba311c6
Publikováno v:
ACS Synthetic Biology. 8:521-531
Mobile genetic elements drive evolution by disrupting genes and rearranging genomes. Eukaryotes have evolved epigenetic mechanisms, including DNA methylation and RNA interference, that silence mobile elements and thereby preserve the integrity of the
Publikováno v:
Journal of Electronic Materials. 47:855-865
This paper reports experimental observations evidencing that the intermetallic compound phase interfaced with Cu in the Al-Cu diffusion couple is most likely α2-Cu3Al phase, not γ-Cu9Al4 phase as previously assumed, and that its growth to a critica
Autor:
Prachi Shah, Alejandro E. Gutierrez, Dennis M. Mishler, Jeffrey E. Barrick, Tien C. Nguyen, Saamiha P. Kenkare, Abigail E. Rex
Publikováno v:
Appl Environ Microbiol
Caffeine and other methylxanthines are stimulant molecules found in formulated beverages, including sodas and energy drinks, and in brewed beverages, such as coffee and teas. Previously, we developed a bioassay for caffeine that involves monitoring t
Climate change is one of the topics that draws full attention from many countries worldwide, including Vietnam, because it affects not only the health of human beings, but also agricultural production, economics, cultural and social activities, secur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd17aeeaba5583247c55f7f807102524
https://doi.org/10.4324/9781315514970-10
https://doi.org/10.4324/9781315514970-10
Publikováno v:
Nucleic Acids Research
Riboswitches are shape-changing regulatory RNAs that bind chemicals and regulate gene expression, directly coupling sensing to cellular actuation. However, it remains unclear how their sequence controls the physics of riboswitch switching and activat
Autor:
Sean P. Leonard, Gabriel A. Suárez, Jeffrey E. Barrick, Brian A. Renda, Benjamin R. Jack, Dacia Leon, Dennis M. Mishler
Publikováno v:
ACS Synthetic Biology. 4:939-943
Unwanted evolution can rapidly degrade the performance of genetically engineered circuits and metabolic pathways installed in living organisms. We created the Evolutionary Failure Mode (EFM) Calculator to computationally detect common sources of gene
Autor:
Justin P. Gallivan, Dennis M. Mishler
Publikováno v:
Nucleic Acids Research
Riboswitches are sequences of RNA that control gene expression via RNA-ligand interactions, without the need for accessory proteins. Riboswitches consist of an aptamer that recognizes the ligand and an expression platform that couples ligand binding