Zobrazeno 1 - 10
of 194
pro vyhledávání: '"M. Miralpeix"'
Autor:
M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw, Ana R. Sousa, Louise J. Fleming, Graham Roberts, Ioannis Pandis, Aruna T. Bansal, Julie Corfield, Scott Wagers, Ratko Djukanovic, Kian Fan Chung, Peter J. Sterk, Jorgen Vestbo, Stephen J. Fowler, S. J. Tebbutt, A. Singh, C. P. Shannon, Y. W. Kim, C. X. Yang, G. M. Gauvreau, J. M. Fitzgerald, L. P. Boulet, P. M. O’Byrne, N. Begley, A. Loudon, D. W. Ray, Selene Baos, Lucía Cremades, David Calzada, Carlos Lahoz, Blanca Cárdaba, Kewal Asosingh, Chris Lauruschkat, Kimberly Queisser, Nicholas Wanner, Kelly Weiss, Weiling Xu, Serpil Erzurum, Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Carolea Logun, Sara Alsaaty, Rosemarie Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron Armando, Edward Dennis, Stewart Levine, James Shelhamer, Kilyong Choi, Snezhina Lazova, Penka Perenovska, Dimitrinka Miteva, Stamatios Priftis, Guergana Petrova, Vassil Yablanski, Evgeni Vlaev, Hristina Rafailova, Takashi Kumae, L. J. Holmes, J. Yorke, D. M. Ryan, Sasawan Chinratanapisit, Khlongtip Matchimmadamrong, Jitladda Deerojanawong, Wissaroot Karoonboonyanan, Paskorn Sritipsukho, Vania Youroukova, Denitsa Dimitrova, Yanina Slavova, Spaska Lesichkova, Iren Tzocheva, Snezhana Parina, Svetla Angelova, Neli Korsun, Mihai Craiu, Iustina Violeta Stan, Matea Deliu, Tolga Yavuz, Matthew Sperrin, Umit M. Sahiner, Danielle Belgrave, Cansin Sackesen Sackesen, Ömer Kalayci, Petar Velikov, Tsvetelina Velikova, Ekaterina Ivanova-Todorova, Kalina Tumangelova-Yuzeir, Dobroslav Kyurkchiev, Spyridon Megremis, Bede Constantinides, Alexandros Georgios Sotiropoulos, Paraskevi Xepapadaki, David Robertson, Nikolaos Papadopoulos, Maxim Wilkinson, Craig Portsmouth, David Ray, Royston Goodacre, Anna Valerieva, Irina Bobolea, Daiana Guillén Vera, Gabriel Gonzalez-Salazar, Carlos Melero Moreno, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, R. Wang, I. Satia, R. Niven, J. A. Smith, T. Southworth, J. Plumb, V. Gupta, J. Pearson, I. Ramis, M. D. Lehner, M. Miralpeix, D. Singh, Imran Satia, Mark Woodhead, Paul O’Byrne, Jaclyn Ann Smith, Cecilia Forss, Peter Cook, Sheila Brown, Freya Svedberg, Katherine Stephenson, Margherita Bertuzzi, Elaine Bignell, Malin Enerbäck, Danen Cunoosamy, Andrew Macdonald, Caini Liu, Liang Zhu, Kiochi Fukuda, Cunjin Zhang, Suidong Ouyang, Xing Chen, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li, Marie-Chantal Larose, Anne-Sophie Archambault, Véronique Provost, Jamila Chakir, Michel Laviolette, Nicolas Flamand, Nicola Logan, Dominik Ruckerl, Judith E. Allen, Tara E. Sutherland, E. Hamelmann, C. Vogelberg, S. Goldstein, G. E. Azzi, M. Engel, R. Sigmund, S. J. Szefler, Raquel Mesquita, Luis Coentrão, Rui Veiga, José-Artur Paiva, Roberto Roncon-Albuquerque, Wendy Vargas Porras, Ana González Moreno, Jesus Macías Iglesias, Gustavo Córdova Ramos, Yesenia Peña Acevedo, Miguel Angel Tejedor Alonso, Maria Del Mar Moro Moro, Irena Krcmova, Jakub Novosad, Nicola Alexander Hanania, Marc Massanari, Heike Hecker, Eric Kassel, Craig Laforce, Kathy Rickard, Sanne Snelder, Gert-Jan Braunstahl, T. L. Jones, D. Neville, E. R. Heiden, E. Lanning, T. Brown, H. Rupani, K. S. Babu, A. J. Chauhan, M. Y. Eldegeir, A. A. Chapman, M. Ferwana, M. Caldron
Publikováno v:
Clinical and Translational Allergy, Vol 7, Iss S2, Pp 1-17 (2017)
Externí odkaz:
https://doaj.org/article/8aa220adbd1b41528cac7a760f22478f
Autor:
P. J. Sterk, John H. Riley, Thomas Sandström, Anna Selby, Laurie Pahus, C. Auffray, Ioannis Pandis, Julie Corfield, R. Djukanovic, K. Sun, Massimo Caruso, Jørgen Vestbo, Matthew J. Loza, Andrew J. Simpson, Dominic Burg, I.M. Adcock, S. Bates, Scott Wagers, Ana R. Sousa, J. Corfield, Ariane H. Wagener, René Lutter, Barbro Dahlén, Ratko Djukanovic, G. Praticò, I. Pandis, N. Mores, G. Hedlin, Navin Rao, I. Horváth, Alexander Mazein, B. De Meulder, Richard G. Knowles, John-Olof Thörngren, Wolfgang Seibold, P H Howarth, Victoria M. Goss, Cristina Gómez, Clare S. Murray, Paul Brinkman, Ildiko Horvath, Anthony D. Postle, M. Caruso, Martina Gahlemann, M. Puig Valls, F.K. Chung, P. Montuschi, Dominick E. Shaw, Kai Sun, Aruna T. Bansal, Fahad Alahmadi, Amphun Chaiboonchoe, Graham Roberts, Kian Fan Chung, Yike Guo, H. Ahmed, Thomas Geiser, Klaus Bønnelykke, M. Miralpeix, Simone Hashimoto, Diane Lefaudeux, S.S. Wagers, D. Erzen, B. Thornton, Florian Singer, Louise Fleming, Stephen J. Fowler, Neil Fitch, P. Bakke, Craig E. Wheelock, Nadja Hawwa Vissing, Tim Higenbottam, Jamie Matthews, F. Singer, S.E. Dahlén, Sarah Masefield, Roelinde Middelveld, Jens M. Hohlfeld, Anthony V. D'Amico, Paul Skipp, W.M.C. van Aalderen, Alan J. Knox, Sven-Erik Dahlén, Andrew Bush, A.T. Bansal, Pieter-Paul Hekking, Joost Brandsma, Stewart Bates, L.J. Fleming, Norbert Krug, N. Krug, Magnus Ericsson, J. Riley, P. Powel, Jacek Musiał, Amanda Roberts, Peter J. Sterk, Ian M. Adcock, Pascal Chanez, Cecile T.J. Holweg, F. Baribaud, Stelios Pavlidis, Veit J. Erpenbeck, Z. Weiszhart, C.E. Wheelock, Ralf Sigmund, James P.R. Schofield, Alexander Manta, Andrea Meiser, Susan J. Wilson, Jeanette Bigler, G. Roberts, M. van Geest, Hans Bisgaard, Urs Frey, Michael Boedigheimer, Per Bakke, Chris Compton, Enrica Bucchioni, Paolo Montuschi, David Myles, E.H.D. Bel, Anna James, Elena Formaggio, Anthony Rowe, Dominic E. Shaw, J. Haughney, P. Chanez, A.R. Sousa, S.J. Fowler, K. Fichtner, B. Dahlèn
Publikováno v:
U-BIOPRED Study Group 2021, ' Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort ', Chest . https://doi.org/10.1016/j.chest.2021.02.023
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Chest
Chest, 2021, 160 (1), pp.53-64. ⟨10.1016/j.chest.2021.02.023⟩
Chest, 160(1), 53-64. American College of Chest Physicians
Alahmadi, Fahad H; Simpson, Andrew J; Gomez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Wheelock, Craig; Shaw, Dominic E; Fleming, Louise J; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R; Knowles, Richard; Bansal, Aruna T; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per S; Caruso, Massimo; Chanez, Pascal; ... (2021). Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort. Chest, 160(1), pp. 53-64. Elsevier 10.1016/j.chest.2021.02.023
Chest
Chest, 2021, 160 (1), pp.53-64. ⟨10.1016/j.chest.2021.02.023⟩
Chest, 160(1), 53-64. American College of Chest Physicians
Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question
Autor:
Johan Kolmert, Cristina Gómez, David Balgoma, Marcus Sjödin, Johan Bood, Jon R. Konradsen, Magnus Ericsson, John-Olof Thörngren, Anna James, Maria Mikus, Ana R. Sousa, John H. Riley, Stewart Bates, Per S. Bakke, Ioannis Pandis, Massimo Caruso, Pascal Chanez, Stephen J. Fowler, Thomas Geiser, Peter Howarth, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Marek Sanak, Annelie Behndig, Dominick E. Shaw, Richard G. Knowles, Cécile T. J. Holweg, Åsa M. Wheelock, Barbro Dahlén, Björn Nordlund, Kjell Alving, Gunilla Hedlin, Kian Fan Chung, Ian M. Adcock, Peter J. Sterk, Ratko Djukanovic, Sven-Erik Dahlén, Craig E. Wheelock, H. Ahmed, C. Auffray, A. T. Bansal, E. H. Bel, J. Bigler, B. Billing, F. Baribaud, H. Bisgaard, M. J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, A. Chaiboonchoe, C. H. Compton, J. Corfield, D. Cunoosamy, A. D’Amico, B. De Meulder, V. J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L. J. Fleming, E. Formaggio, U. Frey, M. Gahlemann, V. Goss, Y. Guo, S. Hashimoto, J. Haughney, P. W. Hekking, T. Higenbottam, J. M. Hohlfeld, A. J. Knox, N. Lazarinis, D. Lefaudeux, M. J. Loza, R. Lutter, A. Manta, S. Masefield, J. G. Matthews, A. Mazein, A. Meiser, R. J. M. Middelveld, M. Miralpeix, N. Mores, C. S. Murray, J. Musial, D. Myles, L. Pahus, S. Pavlidis, A. Postle, P. Powel, G. Praticò, M. PuigValls, N. Rao, A. Roberts, G. Roberts, A. Rowe, T. Sandström, J. P. R. Schofield, W. Seibold, A. Selby, R. Sigmund, F. Singer, P. J. Skipp, M. Smicker, K. Sun, B. Thornton, M. Uddin, W. M. van Aalderen, M. van Geest, J. Vestbo, N. H. Vissing, A. H. Wagener, S. S. Wagers, Z. Weiszhart, S. J. Wilson, J. Östling
Publikováno v:
U-BIOPRED Study Group 2020, ' Urinary Leukotriene E 4 and Prostaglandin D 2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study. ', American Journal of Respiratory and Critical Care Medicine, vol. 203, no. 1, pp. 37-53 . https://doi.org/10.1164/rccm.201909-1869OC
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 2021, 203 (1), pp.37-53. ⟨10.1164/rccm.201909-1869OC⟩
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 2021, 203 (1), pp.37-53. ⟨10.1164/rccm.201909-1869OC⟩
Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins (PGs), cysteinyl leukotrienes (CysLTs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e52ab64017bba43414900205d8dbd0
https://doi.org/10.1164/rccm.201909-1869OC
https://doi.org/10.1164/rccm.201909-1869OC
Autor:
Ana R. Sousa, Anna Selby, Jeanette Bigler, Hans Bisgaard, J. Cunha, I.M. Adcock, A.C.C. Coelho, Ryan Santos Costa, Pieter-Paul Hekking, Louise Fleming, Kai Sun, Amphun Chaiboonchoe, C.V.N. Santana, P. Moura-Santos, Scott Wagers, Ratko Djukanovic, G.P. Pinheiro, G. Hedlin, J.V. de Jesus, Kian Fan Chung, Jacek Musiał, Thomas Geiser, F. Baribaud, Emília Maria Medeiros de Andrade Belitardo, L. Cardoso, Klaus Bønnelykke, Anthony D. Postle, P H Howarth, Adelmir Souza-Machado, Valmar Biao-Lima, Stephen J. Fowler, Craig E. Wheelock, Alvaro A. Cruz, Mauricio Lima Barreto, Maria Ilma Araujo, Massimo Caruso, Laurie Pahus, P. J. Cooper, Florian Singer, W.M.C. van Aalderen, Paulo Augusto Moreira Camargos, Wolfgang Seibold, Ildiko Horvath, René Lutter, P.C.A. Almeida, I. Pandis, Victoria M. Goss, Aruna T. Bansal, John H. Riley, M. Puig Valls, P. Powel, Amanda Roberts, Alexander Mazein, M. Miralpeix, I. Paixao-Araujo, B. De Meulder, Michael Boedigheimer, Isaac Suzart Gomes-Filho, Chris Compton, C. Auffray, Jamie Matthews, Diane Lefaudeux, Elena Formaggio, A.A. Cruz, L.M. Mello, Anthony V. D'Amico, A. Lima-Matos, J. Fernandes, P. J. Sterk, Clare S. Murray, Enrica Bucchioni, Andrea Meiser, D. Erzen, Roelinde Middelveld, M. van Geest, Jørgen Vestbo, Alan J. Knox, Graham Roberts, Norbert Krug, Stewart Bates, G. Santos-Lima, Maggie Davis, Stelios Pavlidis, Paul Skipp, Yike Guo, Ariane H. Wagener, E.V. Ponte, Jens M. Hohlfeld, A. Souza-Machado, M.A. Lessa, I.S. Muniz, C.S. Cruz, Nadja Hawwa Vissing, Neuza Maria Alcantara-Neves, Tim Higenbottam, Navin Rao, Dominic Burg, Sarah Masefield, Z. Weiszhart, Matthew J. Loza, J. Haughney, Simone Hashimoto, Per Bakke, B. Thornton, José Miguel Chatkin, Andrew Bush, SE Dahlen, Joost Brandsma, N. Mores, G. Praticò, Kathleen C. Barnes, Carolina Souza-Machado, Rafael Stelmach, V. Bião-Lima, Martina Gahlemann, Paolo Montuschi, T.M.O. Souza, V.S. Vasquez, Camila Alexandrina Figueiredo, P. Chanez, Eduardo Vieira Ponte, Neil Fitch, Anthony Rowe, Cecile T.J. Holweg, S.J. Wilson, K. Fichtner, Alexander Manta, Lidia Lins, Dominic E. Shaw, David Myles, Julie Corfield, B. Dahlén, Thomas Sandström, Peter J. Sterk, Ian M. Adcock, Ralf Sigmund, James P.R. Schofield, Urs Frey, Laura C. Rodrigues, Leila Denise Alves Ferreira Amorim, E.H.D. Bel, Anna James, R.A. Franco, Paula Cristina Andrade Almeida, Paul Brinkman, H. Ahmed, Veit J. Erpenbeck, Richard G. Knowles
Publikováno v:
Respiratory medicine, 161:105817. W.B. Saunders Ltd
Background Asthma prevalence is 339 million globally. ‘Severe asthma’ (SA) comprises subjects with uncontrolled asthma despite proper management. Objectives To compare asthma from diverse ethnicities and environments. Methods A cross-sectional an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1491bcad6f32c965a6ad0f8da265e17d
http://hdl.handle.net/10044/1/83995
http://hdl.handle.net/10044/1/83995
Autor:
Zala Jevnikar, Jörgen Östling, Elisabeth Ax, Jenny Calvén, Kristofer Thörn, Elisabeth Israelsson, Lisa Öberg, Akul Singhania, Laurie C.K. Lau, Susan J. Wilson, Jonathan A. Ward, Anoop Chauhan, Ana R. Sousa, Bertrand De Meulder, Matthew J. Loza, Frédéric Baribaud, Peter J. Sterk, Kian Fan Chung, Kai Sun, Yike Guo, Ian M. Adcock, Debbie Payne, Barbro Dahlen, Pascal Chanez, Dominick E. Shaw, Norbert Krug, Jens M. Hohlfeld, Thomas Sandström, Ratko Djukanovic, Anna James, Timothy S.C. Hinks, Peter H. Howarth, Outi Vaarala, Marleen van Geest, Henric Olsson, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, F.K. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, V. Goss, Y. Guo, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, A.J. James, R. Knowles, A.J. Knox, N. Krug, D. Lefaudeux, M.J. Loza, A. Manta, J.G. Matthews, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, P. Montuschi, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, A. Postle, P. Powel, G. Praticò, N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, J.P.R. Schofield, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson
Publikováno v:
Jevnikar, Zala; Östling, Jörgen; Ax, Elisabeth; Calvén, Jenny; Thörn, Kristofer; Israelsson, Elisabeth; Öberg, Lisa; Singhania, Akul; Lau, Laurie C K; Wilson, Susan J; Ward, Jonathan A; Chauhan, Anoop; Sousa, Ana R; De Meulder, Bertrand; Loza, Matthew J; Baribaud, Frédéric; Sterk, Peter J; Chung, Kian Fan; Sun, Kai; Guo, Yike; ... (2019). Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of allergy and clinical immunology, 143(2), pp. 577-590. Elsevier 10.1016/j.jaci.2018.05.026
Journal of allergy and clinical immunology, 143(2), 577-590. Mosby Inc.
Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L C K, Wilson, S J, Ward, J A, Chauhan, A, Sousa, A R, De Meulder, B, Loza, M J, Baribaud, F, Sterk, P J, Chung, K F, Sun, K, Guo, Y, Adcock, I M, Payne, D, Dahlen, B, Chanez, P, Shaw, D E, Krug, N, Hohlfeld, J M, Sandström, T, Djukanovic, R, James, A, Hinks, T S C, Howarth, P H, Vaarala, O, Van Geest, M, Olsson, H, Adcock, I M, Ahmed, H, Auffray, C, Bakke, P, Bansal, A T, Baribaud, F, Bates, S, Bel, E H, Bigler, J, Bisgaard, H, Boedigheimer, M J, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Caruso, M, Chaiboonchoe, A, Chanez, P, Chung, F K, Compton, C H, Corfield, J, D'amico, A, Dahlen, S E, De Meulder, B, Djukanovic, R, Erpenbeck, V J, Erzen, D, Fichtner, K, Fitch, N, Fleming, L J, Formaggio, E, Fowler, S J, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P W, Higenbottam, T, Hohlfeld, J M, Holweg, C, Horváth, I, James, A J, Knowles, R, Knox, A J, Krug, N, Lefaudeux, D, Loza, M J, Manta, A, Matthews, J G, Mazein, A, Meiser, A, Middelveld, R J M, Miralpeix, M, Montuschi, P, Mores, N, Murray, C S, Musial, J, Myles, D, Pahus, L, Pandis, I, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Riley, J, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J P R, Seibold, W, Selby, A, Shaw, D E, Sigmund, R, Singer, F, Skipp, P J, Sousa, A R, Sterk, P J, Sun, K, Thornton, B, Van Aalderen, W M, Van Geest, M, Vestbo, J, Vissing, N H, Wagener, A H, Wagers, S S, Weiszhart, Z, Wheelock, C E & Wilson, S J 2018, ' Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.05.026
Journal of allergy and clinical immunology, 143(2), 577-590. Mosby Inc.
Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L C K, Wilson, S J, Ward, J A, Chauhan, A, Sousa, A R, De Meulder, B, Loza, M J, Baribaud, F, Sterk, P J, Chung, K F, Sun, K, Guo, Y, Adcock, I M, Payne, D, Dahlen, B, Chanez, P, Shaw, D E, Krug, N, Hohlfeld, J M, Sandström, T, Djukanovic, R, James, A, Hinks, T S C, Howarth, P H, Vaarala, O, Van Geest, M, Olsson, H, Adcock, I M, Ahmed, H, Auffray, C, Bakke, P, Bansal, A T, Baribaud, F, Bates, S, Bel, E H, Bigler, J, Bisgaard, H, Boedigheimer, M J, Bønnelykke, K, Brandsma, J, Brinkman, P, Bucchioni, E, Burg, D, Bush, A, Caruso, M, Chaiboonchoe, A, Chanez, P, Chung, F K, Compton, C H, Corfield, J, D'amico, A, Dahlen, S E, De Meulder, B, Djukanovic, R, Erpenbeck, V J, Erzen, D, Fichtner, K, Fitch, N, Fleming, L J, Formaggio, E, Fowler, S J, Frey, U, Gahlemann, M, Geiser, T, Goss, V, Guo, Y, Hashimoto, S, Haughney, J, Hedlin, G, Hekking, P W, Higenbottam, T, Hohlfeld, J M, Holweg, C, Horváth, I, James, A J, Knowles, R, Knox, A J, Krug, N, Lefaudeux, D, Loza, M J, Manta, A, Matthews, J G, Mazein, A, Meiser, A, Middelveld, R J M, Miralpeix, M, Montuschi, P, Mores, N, Murray, C S, Musial, J, Myles, D, Pahus, L, Pandis, I, Pavlidis, S, Postle, A, Powel, P, Praticò, G, Rao, N, Riley, J, Roberts, A, Roberts, G, Rowe, A, Sandström, T, Schofield, J P R, Seibold, W, Selby, A, Shaw, D E, Sigmund, R, Singer, F, Skipp, P J, Sousa, A R, Sterk, P J, Sun, K, Thornton, B, Van Aalderen, W M, Van Geest, M, Vestbo, J, Vissing, N H, Wagener, A H, Wagers, S S, Weiszhart, Z, Wheelock, C E & Wilson, S J 2018, ' Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2018.05.026
BackgroundAlthough several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) to asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthmatic patients is unclear.ObjectiveWe sought to explore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab73d68f4dbf9b501c650ac563ec4c72
https://eprints.soton.ac.uk/421475/
https://eprints.soton.ac.uk/421475/
Autor:
Jörgen Östling, Marleen van Geest, James P.R. Schofield, Zala Jevnikar, Susan Wilson, Jonathan Ward, Rene Lutter, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Sven-Erik Dahlen, Stephen J. Fowler, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandström, Kai Sun, Ioannis Pandis, Charles Auffray, Ana R. Sousa, Yike Guo, Ian M. Adcock, Peter Howarth, Kian Fan Chung, Jeanette Bigler, Peter J. Sterk, Paul J. Skipp, Ratko Djukanović, Outi Vaarala, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, K.F. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, Y. Guo, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, P. Howarth, A.J. James, R. Knowles, A.J. Knox, N. Krug, D. Lefaudeux, M.J. Loza, R. Lutter, A. Manta, S. Masefield, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, P. Montuschi, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, P. Powell, G. Praticò, M. Puig N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson, Antonios Aliprantis, David Allen, Kjell Alving, P. Badorrek, David Balgoma, S. Ballereau, Clair Barber, Manohara Kanangana Batuwitage, A. Bautmans, A. Bedding, A.F. Behndig, Jorge Beleta, A. Berglind, A. Berton, Grazyna Bochenek, Armin Braun, D. Campagna, Leon Carayannopoulos, C. Casaulta, Romanas Chaleckis, B. Dahlén, imothy Davison, Jorge De Alba, Inge De Lepeleire, Tamara Dekker, Ingrid Delin, P. Dennison, Annemiek Dijkhuis, Paul Dodson, Aleksandra Draper, K. Dyson, Jessica Edwards, L. El Hadjam, Rosalia Emma, Magnus Ericsson, C. Faulenbach, Breda Flood, G. Galffy, Hector Gallart, D. Garissi, J. Gent, M. Gerhardsson de Verdier, D. Gibeon, Cristina Gomez, Kerry Gove, Neil Gozzard, E. Guillmant-Farry, E. Henriksson, Lorraine Hewitt, U. Hoda, Richard Hu, Sile Hu, X. Hu, E. Jeyasingham, K. Johnson, N. Jullian, Juliette Kamphuis, Erika J. Kennington, Dyson Kerry, G. Kerry, M. Klüglich, Hugo Knobel, Johan Kolmert, J.R. Konradsen, Maxim Kots, Kosmas Kretsos, L. Krueger, Scott Kuo, Maciej Kupczyk, Bart Lambrecht, A.-S. Lantz, Christopher Larminie, L.X. Larsson, P. Latzin, N. Lazarinis, N. Lemonnier, Saeeda Lone-Latif, L.A. Lowe, Alexander Manta, Lisa Marouzet, Jane Martin, Caroline Mathon, L. McEvoy, Sally Meah, A. Menzies-Gow, Leanne Metcalf, Maria Mikus, Philip Monk, Shama Naz, K. Nething, Ben Nicholas, U. Nihlén, Peter Nilsson, R. Niven, B. Nordlund, S. Nsubuga, Antonio Pacino, Susanna Palkonen, J. Pellet, Giorgio Pennazza, Anne Petrén, Sandy Pink, C. Pison, Anthony Postle, Malayka Rahman-Amin, Lara Ravanetti, Emma Ray, Stacey Reinke, Leanne Reynolds, K. Riemann, Martine Robberechts, J.P. Rocha, C. Rossios, Kirsty Russell, Michael Rutgers, G. Santini, Marco Santoninco, M. Saqi, Corinna Schoelch, S. Scott, N. Sehgal, Marcus Sjödin, Barbara Smids, Caroline Smith, Jessica Smith, Katherine M. Smith, P. Söderman, A. Sogbessan, F. Spycher, Doroteya Staykova, S. Stephan, J. Stokholm, K. Strandberg, M. Sunther, M. Szentkereszty, L. Tamasi, K. Tariq, John-Olof Thörngren, Jonathan Thorsen, S. Valente, Marianne van de Pol, C.M. van Drunen, Jonathan Van Eyll, Jenny Versnel, Anton Vink, C. von Garnier, A. Vyas, Frans Wald, Samantha Walker, Kristiane Wetzel, Coen Wiegman, Siân Williams, Xian Yang, Elizabeth Yeyasingham, W. Yu Amgen, W. Zetterquist, Z. Zolkipli, A.H. Zwinderman
Publikováno v:
Journal of Allergy and Clinical Immunology, 144(5), 1198-1213. Mosby Inc.
U-BIOPRED Study Group 2019, ' IL-17-high asthma with features of a psoriasis immunophenotype ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2019.03.027
Journal of allergy and clinical immunology, 144(5), 1198-1213. Mosby Inc.
Östling, J R, van Geest, M, U-BIOPRED Study Group, Schofield, J P R, Jevnikar, Z, Wilson, S, Ward, J, Lutter, R, Shaw, D E, Bakke, P S, Caruso, M, Dahlen, S-E, Fowler, S J, Horváth, I, Krug, N, Montuschi, P, Sanak, M, Sandström, T, Sun, K, Pandis, I, Auffray, C, Sousa, A R, Guo, Y, Adcock, I M, Howarth, P, Chung, K F, Bigler, J, Sterk, P J, Skipp, P J, Djukanović, R & Vaarala, O 2019, ' IL-17–high asthma with features of a psoriasis immunophenotype ', Journal of Allergy and Clinical Immunology, vol. 144, no. 5, pp. 1198-1213 . https://doi.org/10.1016/j.jaci.2019.03.027
U-BIOPRED Study Group 2019, ' IL-17-high asthma with features of a psoriasis immunophenotype ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2019.03.027
Journal of allergy and clinical immunology, 144(5), 1198-1213. Mosby Inc.
Östling, J R, van Geest, M, U-BIOPRED Study Group, Schofield, J P R, Jevnikar, Z, Wilson, S, Ward, J, Lutter, R, Shaw, D E, Bakke, P S, Caruso, M, Dahlen, S-E, Fowler, S J, Horváth, I, Krug, N, Montuschi, P, Sanak, M, Sandström, T, Sun, K, Pandis, I, Auffray, C, Sousa, A R, Guo, Y, Adcock, I M, Howarth, P, Chung, K F, Bigler, J, Sterk, P J, Skipp, P J, Djukanović, R & Vaarala, O 2019, ' IL-17–high asthma with features of a psoriasis immunophenotype ', Journal of Allergy and Clinical Immunology, vol. 144, no. 5, pp. 1198-1213 . https://doi.org/10.1016/j.jaci.2019.03.027
Background The role of IL-17 immunity is well established in patients with inflammatory diseases, such as psoriasis and inflammatory bowel disease, but not in asthmatic patients, in whom further study is required. Objective We sought to undertake a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924ef083d27395d6795993c461f0cec8
https://publica.fraunhofer.de/handle/publica/259279
https://publica.fraunhofer.de/handle/publica/259279
Autor:
Pieter-Paul Hekking, Matt J. Loza, Stelios Pavlidis, Bertrand de Meulder, Diane Lefaudeux, Fred Baribaud, Charles Auffray, Ariane H. Wagener, Paul Brinkman, Rene Lutter, Aruna T. Bansal, Ana R. Sousa, Steve A. Bates, Yannis Pandis, Louise J. Fleming, Dominique E. Shaw, Stephen J. Fowler, Y. Guo, Andrea Meiser, Kai Sun, Julie Corfield, Peter H. Howarth, Elisabeth H. Bel, Ian M. Adcock, Kian Fan Chung, Ratko Djukanovic, Peter J. Sterk, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, F.K. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, P. Howarth, A.J. James, R. Knowles, N. Krug, D. Lefaudeux, M.J. Loza, R. Lutter, A. Manta, S. Masefield, J.G. Matthews, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, P. Powel, G. Praticò, M Puig Valls, N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson
Publikováno v:
Journal of allergy and clinical immunology, 141(4), 1280-1290. Mosby Inc.
U-BIOPRED Study Group 2018, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Journal of Allergy and Clinical Immunology, 141(4), 1280-1290. Mosby Inc.
Hekking, P-P W, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, Y, Flemming, L J, Shaw, D E, Fowler, S, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R & Sterk Peter, J 2017, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
U-BIOPRED Study Group 2018, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Journal of Allergy and Clinical Immunology, 141(4), 1280-1290. Mosby Inc.
Hekking, P-P W, Loza, M J, Pavlidis, S, De Meulder, B, Lefaudeux, D, Baribaud, F, Auffray, C, Wagener, A H, Brinkman, P, Lutter, R, Bansal, A T, Sousa, A R, Bates, S A, Pandis, Y, Flemming, L J, Shaw, D E, Fowler, S, Meiser, A, Sun, K, Corfield, J, Howarth, P, Bel, E H, Adcock, I M, Chung, K F, Djukanovic, R & Sterk Peter, J 2017, ' Pathway discovery using transcriptomic profiles in adult-onset severe asthma ', Journal of Allergy and Clinical Immunology, vol. 141, no. 4, pp. 1280-1290 . https://doi.org/10.1016/j.jaci.2017.06.037
Background: Adult-onset severe asthma is characterized by highly symptomatic disease despite high-intensity asthma treatments. Understanding of the underlying pathways of this heterogeneous disease is needed for the development of targeted treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1f7390120efcc86f31e253222be3f9
https://ruj.uj.edu.pl/xmlui/handle/item/125948
https://ruj.uj.edu.pl/xmlui/handle/item/125948
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Akademický článek
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Summary Neutrophil recruitment and survival are important control points in the development and resolution of inflammatory processes. 15-epi-lipoxin (LX)A4 interaction with formyl peptide receptor 2 (FPR2)/ALX receptor is suggested to enhance anti-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d640dbb65f47697adccc1d774cfb072
https://europepmc.org/articles/PMC3722930/
https://europepmc.org/articles/PMC3722930/