Zobrazeno 1 - 10
of 120
pro vyhledávání: '"M. Michael Sigel"'
Autor:
Nicholas Cohen, M. Michael Sigel
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and mo
Publikováno v:
Cornea. 13:9-15
We have documented the inability of human corneal epithelial-like cells to suppress proliferation of peripheral blood leukocytes (PBLs) induced by allogeneic PBLs in a mixed leukocyte reaction (MLR). Instead, enhanced proliferation of PBLs, albeit sm
Publikováno v:
Endocrinology. 129:2862-2866
Previously, we have reported that interleukin-1 (IL-1) can modulate Leydig cell steroidogenesis. Recently, IL-1-like material has been shown to be present in the testis; however, the cellular source of this material remains unclear. In the present st
Publikováno v:
Cornea. 12(1)
Keratin-positive fibroblast-like epithelial cells (FLE), isolated from human corneo-scleral-conjunctival rims, were shown to inhibit mitogen-driven (concanavalin A) DNA synthesis by murine thymocytes and splenocytes [lymphoreticular cells (LRC)]. The
Publikováno v:
Hospital Practice. 29:15-16
Publikováno v:
Experimental Biology and Medicine. 151:225-230
SummaryLymphocytes of MTV-negative Balb/c mice are sensitive to one or more antigens of MTV as determined by blastogenic transformation and migration inhibition assays. The lymphocytes from MTV-positive Balb/cfC3H mice are nonre-sponsive in these ass
Publikováno v:
The Journal of Immunology. 122:8-11
Extracts of a marine tunicate, Ecteinascidia turbinata (Ete) were previously shown to be capable of suppressing humoral and cellular immune responses in vivo and in vitro. In the present work we have examined the mechanisms of suppression in Ete-trea
Autor:
George Melnykovych, John D. Biggers, Vincent J. Cristofalo, Donald K. Dougall, Virginia J. Evans, W. F. Hink, G. D. Hsiung, Frederick H. Kasten, Kenneth S. McCarty, Roland M. Nardone, George H. Rothblat, M. Michael Sigel, Ronald Sinclair
Publikováno v:
In Vitro. 9:339-349
Autor:
Edgar M. Huggins, M. Michael Sigel, James A. Hightower, Steven S. Hayasaka, Larry J. Mccumber, James F. Davis
Publikováno v:
American Zoologist. 23:221-227
The tunicate Ecteinascidia turbinata contains a substance or substances capable of exerting a number of biological effects. Extracts of tunicate tissues have been shown to kill tumor cells in vitro and arrest tumor growth in vivo . The extracts also
Autor:
M. Michael Sigel, Diana M. Lopez
Publikováno v:
International Journal of Cancer. 18:808-812
A new cytotoxicity assay for the study of tumor antigens is described. Splenocytes from normal and mammary-tumor-bearing BALB/c mice were depleted of glass-adherent cells, exposed to various concentrations of tumor extracts and mixed with 51Cr-labell