Zobrazeno 1 - 10
of 488
pro vyhledávání: '"M. Michael Gromiha"'
Publikováno v:
BioMedInformatics, Vol 4, Iss 1, Pp 542-548 (2024)
Artificial intelligence (AI), a branch of computer science, involves developing intelligent computer programs to mimic human intelligence and automate various processes [...]
Externí odkaz:
https://doaj.org/article/75768f9b3665474caf4755c7a93da472
Publikováno v:
Current Research in Structural Biology, Vol 7, Iss , Pp 100132- (2024)
AIDS is one of the deadliest diseases in the history of humankind caused by HIV. Despite the technological development, curtailing the viral infection inside human host still remains a challenge. Therapies such as HAART uses a combination of drugs to
Externí odkaz:
https://doaj.org/article/a39162eea3774447bffae57bee7ff42c
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1205-1226 (2023)
Membrane proteins mediate a wide spectrum of biological processes, such as signal transduction and cell communication. Due to the arduous and costly nature inherent to the experimental process, membrane proteins have long been devoid of well-resolved
Externí odkaz:
https://doaj.org/article/a07ccb0308be46bc9e711f9932f11f53
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/5b4e5a8f080d4bc69726be8845ad5c39
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Mitigating the devastating effect of COVID-19 is necessary to control the infectivity and mortality rates. Hence, several strategies such as quarantine of exposed and infected individuals and restricting movement through lockdown of geograph
Externí odkaz:
https://doaj.org/article/9491c200cd9e4f0f893a124528e7388e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The light chain (AL) amyloidosis is caused by the aggregation of light chain of antibodies into amyloid fibrils. There are plenty of computational resources available for the prediction of short aggregation-prone regions within proteins. How
Externí odkaz:
https://doaj.org/article/4fa62a20ac6040f6894d6f47565edcc3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The urgent need for a treatment of COVID-19 has left researchers with limited choice of either developing an effective vaccine or identifying approved/investigational drugs developed for other medical conditions for potential repurposing, th
Externí odkaz:
https://doaj.org/article/91d1b92f687040aebb2d043b3dfc7e60
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Alzheimer’s disease (AD) and Parkinson’s disease (PD) are well-known neuronal degenerative disorders that share common pathological events. Approved medications alleviate symptoms but do not address the root cause of the disease. Energy dysfuncti
Externí odkaz:
https://doaj.org/article/5bac47577c474c7c93a45722a51758e5
Autor:
Vignayanandam Ravindernath Muddapu, S. Akila Parvathy Dharshini, V. Srinivasa Chakravarthy, M. Michael Gromiha
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic lateral sclerosis, are a prominent class of neurological diseases currently without a cure. They are characterized by an inexorable loss of a specific type of neu
Externí odkaz:
https://doaj.org/article/6221f0cbdda643de92f543cbd509af8a
Publikováno v:
Applied Sciences, Vol 11, Iss 1, p 213 (2020)
N6-methyladenosine (m6A) editing is the most common RNA modification known to contribute to various biological processes. Nevertheless, the mechanism by which m6A regulates transcription is unclear. Recently, it was proposed that m6A controls transcr
Externí odkaz:
https://doaj.org/article/d9c519b0d8444225a2920bad4b9d1eb2