Zobrazeno 1 - 10
of 173
pro vyhledávání: '"M. Michael Barmada"'
Autor:
Vikesh K. Singh, David C. Whitcomb, Peter A. Banks, Samer AlKaade, Michelle A. Anderson, Stephen T. Amann, Randall E. Brand, Darwin L. Conwell, Gregory A. Cote, Timothy B. Gardner, Andres Gelrud, Nalini Guda, Christopher E. Forsmark, Michele Lewis, Stuart Sherman, Thiruvengadam Muniraj, Joseph Romagnuolo, Xiaoqing Tan, Gong Tang, Bimaljit S. Sandhu, Adam Slivka, C. Mel Wilcox, Dhiraj Yadav, Peter Banks, Darwin Conwell, Simon K. Lo, Timothy Gardner, John Baillie, Robert Hawes, Christopher Lawrence, Babak Etemad, Mark DeMeo, Michael Kochman, Judah N. Abberbock, M. Michael Barmada, Emil Bauer, Elizabeth Kennard, Jessica LaRusch, Michael O'Connell, Kimberly Stello, Jyothsna Talluri, Stephen R. Wisniewski, Frank Burton, James DiSario, Mary Money, William Steinberg
Publikováno v:
Pancreatology
INTRODUCTION: The mechanistic definition of chronic pancreatitis (CP) identifies acute pancreatitis (AP) as a precursor stage. We hypothesized that clinical AP frequently precedes the diagnosis of CP and is associated with patient- and disease-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8d685701c5f9efe0dd0a49b72fe138
https://europepmc.org/articles/PMC10122210/
https://europepmc.org/articles/PMC10122210/
Autor:
Uma R Chandran, Olga P Medvedeva, M Michael Barmada, Philip D Blood, Anish Chakka, Soumya Luthra, Antonio Ferreira, Kim F Wong, Adrian V Lee, Zhihui Zhang, Robert Budden, J Ray Scott, Annerose Berndt, Jeremy M Berg, Rebecca S Jacobson
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165395 (2016)
The Cancer Genome Atlas Project (TCGA) is a National Cancer Institute effort to profile at least 500 cases of 20 different tumor types using genomic platforms and to make these data, both raw and processed, available to all researchers. TCGA data are
Externí odkaz:
https://doaj.org/article/cbff19bf021f4dc4a1edfcf54f7fcaea
Autor:
Albert Geskin, Elizabeth Legowski, Anish Chakka, Uma R Chandran, M Michael Barmada, William A LaFramboise, Jeremy Berg, Rebecca S Jacobson
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131166 (2015)
Next Generation Sequencing (NGS) methods are driving profound changes in biomedical research, with a growing impact on patient care. Many academic medical centers are evaluating potential models to prepare for the rapid increase in NGS information ne
Externí odkaz:
https://doaj.org/article/5c1a3bfa87684022aecab460fa3c1926
Autor:
András Szabó, Prachand Issarapu, Emmanuelle Masson, Peter Bugert, Denise Lasher, Sumit Paliwal, Claudia Ruffert, Shin Hamada, K. Radha Mani, Helmut Laumen, Jian-Min Chen, Atsushi Masamune, David A. Groneberg, Katharina Seltsam, Kiyoshi Kume, Xunjun Xiao, Maren Ewers, Eriko Nakano, M. Michael Barmada, Tooru Shimosegawa, Jonas Rosendahl, Giriraj R. Chandak, Thomas Müller, Mark E. Lowe, Miklós Sahin-Tóth, Heiko Witt, Seema Bhaskar, David C. Whitcomb, Claude Férec
Publikováno v:
American Journal of Gastroenterology. 114:974-983
OBJECTIVES. Premature activation of the digestive protease trypsin within the pancreatic parenchyma is a critical factor in the pathogenesis of pancreatitis. Alterations in genes that affect intra-pancreatic trypsin activity are associated with chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f489f34cd4a57579c412918eeeab3
https://doi.org/10.14309/ajg.0000000000000051
https://doi.org/10.14309/ajg.0000000000000051
Autor:
Jessica LaRusch, Jinsei Jung, Ignacio J General, Michele D Lewis, Hyun Woo Park, Randall E Brand, Andres Gelrud, Michelle A Anderson, Peter A Banks, Darwin Conwell, Christopher Lawrence, Joseph Romagnuolo, John Baillie, Samer Alkaade, Gregory Cote, Timothy B Gardner, Stephen T Amann, Adam Slivka, Bimaljit Sandhu, Amy Aloe, Michelle L Kienholz, Dhiraj Yadav, M Michael Barmada, Ivet Bahar, Min Goo Lee, David C Whitcomb, North American Pancreatitis Study Group
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004376 (2014)
CFTR is a dynamically regulated anion channel. Intracellular WNK1-SPAK activation causes CFTR to change permeability and conductance characteristics from a chloride-preferring to bicarbonate-preferring channel through unknown mechanisms. Two severe C
Externí odkaz:
https://doaj.org/article/6a2c7e398d0d4ee099822dc3df1afa18
Autor:
Zaheda H Radwan, Xingbin Wang, Fahad Waqar, Dilek Pirim, Vipavee Niemsiri, John E Hokanson, Richard F Hamman, Clareann H Bunker, M Michael Barmada, F Yesim Demirci, M Ilyas Kamboh
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114618 (2014)
Although common APOE genetic variation has a major influence on plasma LDL-cholesterol, its role in affecting HDL-cholesterol and triglycerides is not well established. Recent genome-wide association studies suggest that APOE also affects plasma vari
Externí odkaz:
https://doaj.org/article/ee457e5d4a5b4e5988923cf5bce136ce
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95152 (2014)
Late-onset Alzheimer's disease (LOAD) is a multifactorial disorder with over twenty loci associated with disease risk. Given the number of genome-wide significant variants that fall outside of coding regions, it is possible that some of these variant
Externí odkaz:
https://doaj.org/article/623033e9ca72455b85f5ec18843261f1
Autor:
Xiaojing Zheng, F Yesim Demirci, M Michael Barmada, Gale A Richardson, Oscar L Lopez, Robert A Sweet, M Ilyas Kamboh, Eleanor Feingold
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111462 (2014)
Epidemiological and genetic studies suggest that schizophrenia and autism may share genetic links. Besides common single nucleotide polymorphisms, recent data suggest that some rare copy number variants (CNVs) are risk factors for both disorders. Bec
Externí odkaz:
https://doaj.org/article/1c81f8826cc049e4868dc682abfb73a6
Publikováno v:
Biological Research For Nursing. 20:126-136
Preeclampsia is a complex genetic disorder with an incompletely understood pathogenesis. Its phenotype may be better elucidated by integrating symptoms. This study aimed to identify symptoms by gestational age and associations with novel preeclampsia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbf4d41bc6b51db5b75084ef5ba48bc
https://doi.org/10.1177/1099800417754140
https://doi.org/10.1177/1099800417754140
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22075 (2011)
A genome-wide association study (GWAS) typically involves examining representative SNPs in individuals from some population. A GWAS data set can concern a million SNPs and may soon concern billions. Researchers investigate the association of each SNP
Externí odkaz:
https://doaj.org/article/5030af119f2e465a8ab7c416d9b9d35d