Výsledky vyhledávání - "M. Mendelsohn"

Akademický článek

Topical Isotretinoin (TMB-001) Treatment for 12 Weeks Did Not Result in Clinically Relevant Laboratory Abnormalities in Participants with Congenital Ichthyosis in the Phase 2b CONTROL Study

Autor: Kalyani Marathe, Joyce M. C. Teng, Scott Guenthner, Christopher G. Bunick, Steven Kempers, Kimmie Eads, Leslie Castelo-Soccio, Alan M. Mendelsohn, Jessica Raiz, Dédée F. Murrell

Publikováno v: Dermatology and Therapy, Vol 13, Iss 6, Pp 1255-1264 (2023)

Abstract Introduction Treatment with oral retinoids can be effective in patients with congenital ichthyosis (CI) but may be associated with clinically significant laboratory changes. In this Phase 2b CONTROL study analysis, we characterize the effect

Externí odkaz: https://doaj.org/article/0589bfedc89443abbc72105e37c33aed

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Akademický článek

Cost-effectiveness analysis of two-way texting for post-operative follow-up in Zimbabwe's voluntary medical male circumcision program.

Autor: Joseph B Babigumira, Scott Barnhart, Joanna M Mendelsohn, Vernon Murenje, Mufuta Tshimanga, Christina Mauhy, Isaac Holeman, Sinokuthemba Xaba, Marrianne M Holec, Batsirai Makunike-Chikwinya, Caryl Feldacker

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0239915 (2020)

ObjectiveAlthough adverse events (AEs) following voluntary medical male circumcision (VMMC) are rare, their prompt ascertainment and management is a marker of quality care. The use of two-way text messaging (2wT) for client follow-up after VMMC reduc

Externí odkaz: https://doaj.org/article/3c282b0da83d4fa096e4fd3f9702765f

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When sexual identity and sexual behaviors do not align: The prevalence of discordance and its physical and psychological health correlates

Autor: David M. Mendelsohn, Allen M. Omoto, Karen Tannenbaum, Christopher S. Lamb

Publikováno v: Stigma Health

Although scholarly work on the complexity of human sexuality has increasingly been a focus of scholarship, comparatively little research has focused on the phenomenon of mismatch, or discordance, between different aspects of sexuality. This study use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541d37c84c2694cd43b40ad3819392a6
https://doi.org/10.1037/sah0000338

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Characteristics and outcomes for participants with congenital ichthyosis who responded to treatment with the topical isotretinoin formulation TMB-001: results from the Phase IIb CONTROL study

Autor: Christopher G. Bunick, Joyce M.C. Teng, Scott Guenthner, Kalyani Marathe, Steven Kempers, Kimmie Eads, Leslie Castelo-Soccio, Alan M. Mendelsohn, Jessica Raiz, Dédée F. Murrell

Publikováno v: Clinical and Experimental Dermatology.

Background Emollients and keratolytics are frequently used to manage symptoms of congenital ichthyosis (CI). Systemic retinoid treatment is complicated by teratogenicity and dose-limiting adverse effects. Objectives This analysis from the randomized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::929d6ec16aaafebddd30b312edc4f2c3
https://doi.org/10.1093/ced/llad105

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Phase IIb randomized CONTROL study demonstrates a novel topical isotretinoin formulation, TMB-001, is safe and effective in participants with either recessive X-linked or autosomal recessive lamellar congenital ichthyosis

Autor: Dedee F Murrell, Joyce M C Teng, Scott Guenthner, Kalyani Marathe, Steven Kempers, Kimmie Eads, Leslie Castelo-Soccio, Alan M Mendelsohn, Jessica Raiz, Christopher G Bunick

Publikováno v: Clinical and Experimental Dermatology.

BackgroundIn two severe congenital ichthyosis subtypes, autosomal recessive lamellar ichthyosis (ARCI-LI) and X-linked recessive ichthyosis (XLRI), cutaneous manifestations include widespread scaling. Approved topical treatment options are limited to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::005dcf3a2e6299e088207f1355d623f9
https://doi.org/10.1093/ced/llad033

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1462. Validating a claims-based algorithm for Lyme Disease in Massachusetts

Autor: Sheryl A Kluberg, Sarah J Willis, Noelle M Cocoros, Susan R Forrow, Emma R Hoffman, Robert M Jin, Aaron M Mendelsohn, Young Hee Nam, Bradford J Gessner, Sarah J Pugh, James H Stark, Cameron T Nutt, Nathan Petrou, Chanu Rhee, Meera Sury, John Aucott

Publikováno v: Open Forum Infectious Diseases. 9

Background Lyme disease (LD) is the fifth most reported notifiable disease in the US, but the true disease burden remains unknown due to inconsistent reporting. Claims-based algorithms estimate a ≥10-fold higher incidence compared to notifiable-dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbf7bd57c8faad36eab2862a335f8f9f
https://doi.org/10.1093/ofid/ofac492.1289

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Efficacy and safety of tildrakizumab in patients with active psoriatic arthritis: results of a randomised, double-blind, placebo-controlled, multiple-dose, 52-week phase IIb study

Autor: Stephen J. Rozzo, Alan M. Mendelsohn, Alice B. Gottlieb, Siba P. Raychaudhuri, Proton Rahman, Saima Chohan, Philip J. Mease, Richard C Chou, Michael E. Luggen, Ferran J Garcia Fructuoso

Publikováno v: Annals of the Rheumatic Diseases

ObjectivesTo evaluate efficacy and safety of the anti-interleukin-23p19 monoclonal antibody tildrakizumab in patients with psoriatic arthritis (PsA).MethodsIn this randomised, double-blind, placebo-controlled, phase IIb study, patients with active Ps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45699aa413018d161e9029b076da7135
https://doi.org/10.1136/annrheumdis-2020-219014

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Clinical implications and predictive values of early PASI responses to tildrakizumab in patients with moderate-to-severe plaque psoriasis

Autor: Jingchuan Zhang, Alan M. Mendelsohn, Joseph F. Merola, Alice B. Gottlieb, Yang Zhao, David M. Pariser, Steven R. Feldman

Publikováno v: Journal of Dermatological Treatment. 33:1670-1675

To evaluate whether early Psoriasis Area Severity Index (PASI) improvements can predict week 28 tildrakizumab responders and nonresponders.Psoriasis patients pooled from two tildrakizumab phase 3 trials randomized to receive tildrakizumab 100 mg at w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69f75cc419f1f199ef56cf10fbdc38e
https://doi.org/10.1080/09546634.2021.1898528

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Double-brooding in Southern Yellow-billed Hornbills Tockus leucomelas

Autor: John M. Mendelsohn, Laurie Marker, William Versfeld, Mark T. Stanback, Matti T. Nghikembua, David Millican

Publikováno v: Ostrich. 92:105-112

Double-brooding is an avian breeding strategy where birds produce at least two successful nests in a single season. Double-brooding is seen most frequently in small passerines for which the breeding season is lengthy enough that they can easily fit i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f7e28a94457ddbfde666fb2de988868
https://doi.org/10.2989/00306525.2021.1891479

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Efficacy and safety of tildrakizumab in Japanese patients with moderate to severe plaque psoriasis: Results from a 64‐week phase 3 study (reSURFACE 1)

Autor: Yukari Okubo, Shigetoshi Sano, Masaru Honma, Alan M. Mendelsohn, Yayoi Tada, Atsuyuki Igarashi, Akimichi Morita, Hidemi Nakagawa, Shinichi Imafuku, Masaki Kawamura, Mamitaro Ohtsuki

Publikováno v: The Journal of Dermatology

Tildrakizumab is a high‐affinity, humanized immunoglobulin G1κ, anti‐interleukin‐23p19 monoclonal antibody recently approved in Japan for treatment of plaque psoriasis. We report results from Japanese patients treated with tildrakizumab in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97908d702d03072b6cbed06c1364628
http://europepmc.org/articles/PMC8247960

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