Zobrazeno 1 - 10
of 23
pro vyhledávání: '"M. McLean Bolton"'
Autor:
Audrey Bonnan, Matthew M. J. Rowan, Christopher A. Baker, M. McLean Bolton, Jason M. Christie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Plastic reweighting of parallel fiber synaptic strength is a mechanism for the acquisition of cerebellum-dependent motor learning. Here, the authors found that optogenetic activation of PCs generates dendritic Ca2+ signals that induce plasticity in v
Externí odkaz:
https://doaj.org/article/231e3ecfe8014b23afce4d2cc0b1ebd2
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Identification of candidate risk genes and alteration in the expression of proteins involved in regulating inhibitory neuron function in various psychiatric disorders, support the notion that GABAergic neuron dysfunction plays an important role in di
Externí odkaz:
https://doaj.org/article/18b9b7bfe05c4106aa6f5a4086af62ee
Autor:
Douglas Asede, Divyesh Doddapaneni, Abigail Chavez, James Okoh, Sabah Ali, Carolyn Von-Walter, M. McLean Bolton
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109151- (2021)
Summary: GABAergic neurons regulate different aspects of information processing in the amygdala. Among these are clusters of intercalated cells (ITCs), which have been implicated in fear-related behaviors. Although a few of the ITC clusters have been
Externí odkaz:
https://doaj.org/article/bf447f71f71c4eb58c068aad6c0e453b
Amygdala Intercalated Cells: Gate Keepers and Conveyors of Internal State to the Circuits of Emotion
Publikováno v:
J Neurosci
Generating adaptive behavioral responses to emotionally salient stimuli requires evaluation of complex associations between multiple sensations, the surrounding context, and current internal state. Neural circuits within the amygdala parse this emoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfac919a61d6e485f494b02c5a6cfcc1
https://europepmc.org/articles/PMC9761677/
https://europepmc.org/articles/PMC9761677/
Publikováno v:
eLife, Vol 5 (2016)
We describe refinements in optogenetic methods for circuit mapping that enable measurements of functional synaptic connectivity with single-neuron resolution. By expanding a two-photon beam in the imaging plane using the temporal focusing method and
Externí odkaz:
https://doaj.org/article/eaea621c155d4bc398ca76d2d3162192
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry
Translational Psychiatry
Neurexins are a family of presynaptic cell adhesion proteins that regulate synaptic structure and maintain normal synaptic transmission. Mutations in the α-isoform of neurexin1-gene (NRXN1α) are linked with cognitive and emotional dysregulation, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaf2f03fc8fda2254f8a5dc8bf60c7c
http://link.springer.com/article/10.1038/s41398-020-00926-y
http://link.springer.com/article/10.1038/s41398-020-00926-y
Publikováno v:
Frontiers in Synaptic Neuroscience
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Identification of candidate risk genes and alteration in the expression of proteins involved in regulating inhibitory neuron function in various psychiatric disorders, support the notion that GABAergic neuron dysfunction plays an important role in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043cc792148d53612b18f65c918ee206
https://doi.org/10.3389/fnsyn.2021.697110
https://doi.org/10.3389/fnsyn.2021.697110
Publikováno v:
Cerebral Cortex. 29:4488-4505
The mammalian cerebral cortex is divided into different areas according to their function and pattern of connections. Studies comparing primary visual (V1) and prefrontal cortex (PFC) of primates have demonstrated striking pyramidal neuron (PN) speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7847e1453af78c15ed7db7b4d43671f1
https://doi.org/10.1093/cercor/bhy326
https://doi.org/10.1093/cercor/bhy326
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
The signals in cerebellar Purkinje cells sufficient to instruct motor learning have not been systematically determined. Therefore, we applied optogenetics in mice to autonomously excite Purkinje cells and measured the effect of this activity on plast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb4e1f0d3f803ac89031e36a9fde078
https://doi.org/10.1038/s41467-021-22405-8
https://doi.org/10.1038/s41467-021-22405-8
Publikováno v:
Brain Structure & Function
Amygdala plays crucial roles in emotional learning. The lateral amygdala (LA) is the input station of the amygdala, where learning related plasticity occurs. The LA is cortical like in nature in terms of its cellular make up, composed of a majority o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41d9fcb373101228805b96a5217132e
https://doi.org/10.1007/s00429-020-02051-4
https://doi.org/10.1007/s00429-020-02051-4