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Akademický článek
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Autor:
Ryan deOgburn, Alan Dardik, Jose O Leite, Mary M. McGrane, Randy Su, Joan A. Smyth, Joseph Ratliff, Maria Luz Fernandez, Jeff S. Volek
Publikováno v:
Atherosclerosis. 209:442-448
Low-carbohydrate diets (LCD) efficiently induce weight loss and favorably affect plasma lipids, however, the effect of LCD on atherosclerosis is still argued.To evaluate the effect of LCD on the prevention of atherosclerosis.Twenty guinea pigs were f
Publikováno v:
The Journal of Nutrition. 137:1165-1170
We previously demonstrated that a diet therapy involving consumption of 7.28 g psyllium (PSY) and 2 g of plant sterols (PS) per day reduced LDL cholesterol from 3.6 +/- 0.7 to 3.1 +/- 0.8 mmol/L (P < 0.01) and decreased the number of intermediate den
Publikováno v:
The Journal of Nutritional Biochemistry. 18:206-214
Vitamin A deficiency decreases hepatic phosphoenolpyruvate carboxykinase (PEPCK) gene expression in mice and expression is restored with retinoic acid treatment in vivo. This report examines further the mechanism of retinoid regulation of the PEPCK g
Autor:
David D. Waters, Mary M. McGrane, Maria Luz Fernandez, Kristin L. Herron, Ingrid E. Lofgren, Richard M. Clark, Jose M. Ordovas
Publikováno v:
The Journal of Nutrition. 136:1161-1165
The ATP binding cassette G5 (ABCG5) polymorphisms have been postulated to play a role in the response to dietary cholesterol. The objective of this study was to examine the contribution of the ABCG5 polymorphism on the plasma response to consumption
Publikováno v:
The Journal of Nutritional Biochemistry. 16:722-728
We have demonstrated that SC-435, an apical sodium codependent bile acid transporter (ASBT) inhibitor, lowers plasma low-density lipoprotein cholesterol (LDL-C) concentrations in guinea pigs. The purpose of this study was to further examine the hypoc
Autor:
Kelly B. Scribner, Mary M. McGrane
Publikováno v:
The Journal of Nutrition. 133:4112-4117
Phosphoenolpyruvate carboxykinase (PEPCK) gene expression is decreased in vitamin A-deficient (VAD) mice. However, the underlying molecular mechanism at the PEPCK promoter that contributes to this alteration in gene expression remains unexplained and
Publikováno v:
The Journal of Nutrition. 133:2131-2136
Expression of the phosphoenolpyruvate carboxykinase (PEPCK) gene is repressed during fetal liver development and activated at birth. It has been shown that the PEPCK gene is a retinoid-responsive gene, but whether it is regulated by vitamin A in the
Publikováno v:
Journal of the Science of Food and Agriculture. 82:1780-1790
Two experiments were conducted to evaluate the effects of phosphorus (P) level and calcium (Ca)/total P (tP) ratio on the efficacy of microbial phytase. Experiment 1 examined the effects of P concentration and microbial phytase inclusion on mineral e