Zobrazeno 1 - 10
of 85
pro vyhledávání: '"M. Mauchauffe"'
Autor:
Olivier Bernard, L E Huang, Florence Nguyen-Khac, E Ravet, Jacques Ghysdael, Rodolphe G. Lopez, Serge Fichelson, Alan D. Friedman, V. Della Valle, M. Mauchauffe
Publikováno v:
Oncogene. 25:4840-4847
The transcription factor hypoxia inducible factor 1 (HIF1), an HIF1alpha-aryl hydrocarbon receptor nuclear translocator (ARNT) dimeric factor, is essential to the cellular response to hypoxia. We described a t(1;12)(q21;p13) chromosomal translocation
Autor:
Hung Bui, Nicole Dastugue, Françoise Valensi, Thomas Mercher, Maryvonne Busson-Le Coniat, Olivier Bernard, Paola Ballerini, Beatrice Pellegrino, Florence Nguyen Khac, Francine Mugneret, Roland Berger, Isabelle Radford, M. Mauchauffe
Publikováno v:
Genes, Chromosomes and Cancer. 33:22-28
Translocation t(1;22)(p13;q13) is associated with a peculiar subtype of acute megakaryocytic leukemia (M7) occurring in infants. We have recently characterized a fusion gene, OTT-MAL, resulting from this translocation. We now report three additional
Autor:
Maryvonne Busson-Le Coniat, Thomas Mercher, Florence Nguyen Khac, Nicole Dastugue, Roland Berger, Lætitia Gressin, Olivier Bernard, Thierry Leblanc, M. Mauchauffe, Richard Monni, Francine Mugneret
Publikováno v:
Proceedings of the National Academy of Sciences. 98:5776-5779
The recurrent t(1;22)(p13;q13) translocation is exclusively associated with infant acute megakaryoblastic leukemia. We have identified the two genes involved in this translocation. Both genes possess related sequences in the Drosophila genome. The ch
The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion
Autor:
Maryvonne Busson-Le Coniat, Florence Salomon-Nguyen, Olivier Bernard, Roland Berger, M. Mauchauffe, Véronique Della-Valle, Jacques Ghysdael
Publikováno v:
Proceedings of the National Academy of Sciences. 97:6757-6762
The TEL / ETV6 gene is located at 12p13 and encodes a member of the ETS family of transcription factors. Translocated ETS leukemia (TEL) is frequently involved in chromosomal translocations in human malignancies, usually resulting in the expression o
Autor:
Jacques Ghysdael, M Le Coniat, Hélène Poirel, M. Mauchauffe, Cécile Oury, Estelle Duprez, Olivier Bernard, Serge Romana, Andreas Tsapis, Y. Laabi, Roland Berger, Clémence Carron
Publikováno v:
Oncogene. 14:349-357
The human TEL gene is involved in several 12p13 chromosomal abnormalities present in various human hematological malignancies, the most frequent being the t(12;21)(p13;q22), specific for childhood acute lymphoblastic leukemia. The predicted product o
Autor:
Serge Romana, Philippe Jonveaux, Elizabeth Macintyre, Roland Berger, M. Mauchauffe, M Leconiat, M. A. Flexor, Olivier Bernard, Hélène Poirel
Publikováno v:
Blood. 86:4263-4269
The recurrent t(12;21)(p12;q22) translocation fuses two genes, TEL and AML1, that have previously been shown to be independently involved in myeloid malignant proliferations. A search for rearrangement of the TEL locus in the region known to be invol
Autor:
Roland Berger, M Busson-LeConiat, Marie-Thérèse Daniel, R Monni, L Gressin, Thomas Mercher, Paola Ballerini, Olivier Bernard, M. Mauchauffe, R Heilig, F Nguyen Khac, P Pasturaud, V Della Valle, Michel Lessard, Virginie Penard-Lacronique
Publikováno v:
Leukemia. 15(10)
FISH identified a cryptic t(5;14)(q35;q32) in T acute lymphoblastic leukemia (ALL), whereas it was not observed in B ALL samples. This translocation is present in five out of 23 (22%) children and adolescents with T ALL tested. RanBP17, a gene coding
Autor:
Richard Monni, Fabrice Gouilleux, Roland Berger, Jacques Ghysdael, M. Mauchauffe, Virginie Penard-Lacronique, Sylvie Gisselbrecht, Susana Constantino Rosa Santos, Olivier Bernard
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2001, 20 (7), pp.849-858. ⟨10.1038/sj.onc.1204201⟩
Oncogene, 2001, 20 (7), pp.849-858. ⟨10.1038/sj.onc.1204201⟩
Oncogene, Nature Publishing Group, 2001, 20 (7), pp.849-858. ⟨10.1038/sj.onc.1204201⟩
Oncogene, 2001, 20 (7), pp.849-858. ⟨10.1038/sj.onc.1204201⟩
International audience; The leukemia-associated TEL-Jak2 fusion protein possesses a constitutive tyrosine kinase activity and transforming properties in hematopoietic cell lines and animal models. In the murine pro-B Ba/F3 cell line, this fusion cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cada2ed62ba6dd147a3fabdf9a41c16f
https://hal-univ-tours.archives-ouvertes.fr/hal-02427368
https://hal-univ-tours.archives-ouvertes.fr/hal-02427368
Autor:
Fabrice Gouilleux, Jacques Ghysdael, Roland Berger, Stephanie Dumon, Patrick Mayeux, M. Mauchauffe, Sylvie Gisselbrecht, Virginie Lacronique, Richard Monni, Anthony Boureux, Olivier A. Bernard
Publikováno v:
Blood
Blood, American Society of Hematology, 2000, 95 (6), pp.2076-2083. ⟨10.1182/blood.V95.6.2076⟩
ResearcherID
Europe PubMed Central
Blood, American Society of Hematology, 2000, 95 (6), pp.2076-2083. ⟨10.1182/blood.V95.6.2076⟩
ResearcherID
Europe PubMed Central
The involvement of the cytokine signaling pathway in oncogenesis has long been postulated. Recently, rearrangements of the gene encoding the tyrosine Janus kinase 2 (JAK2) have been reported in human leukemias indicating a direct JAK-signal transduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70df9eda929f99e7826b64eac4d24dbf
https://hal-univ-tours.archives-ouvertes.fr/hal-02427379/document
https://hal-univ-tours.archives-ouvertes.fr/hal-02427379/document
Autor:
Hélène Poirel, M. Mauchauffe, Serge Romana, M Busson-Le Coniat, Roland Berger, V Della Valle, Olivier Bernard
Publikováno v:
Leukemia. 13(11)
The TEL gene is involved in several chromosomal abnormalities of human hematopoietic malignancies. The chromosome 12 breakpoints frequently lie within the fifth intron of the gene, particularly in the most frequent translocation involving TEL, the t(