Zobrazeno 1 - 10
of 176
pro vyhledávání: '"M. Marvola"'
Publikováno v:
Die Pharmazie. 56(9)
In chronopharmacotherapy, circadian changes in disease symptoms are taken into account. Press-coated, time-controlled release tablets containing pseudoephedrine hydrochloride as a model drug have been formulated and the suitability of this highly sol
Publikováno v:
Acta Anaesthesiologica Scandinavica. 35:575-577
To compare the effectiveness of propofol given intravenously and rectally, ten piglets received propofol intravenously. On the next day, the same piglets and five other piglets were given suppositories containing propofol. Serial blood samples were c
Publikováno v:
Oral Oncology Supplement. 1:75-76
Publikováno v:
Pharmaceutical research. 8(8)
Erythromycin acistrate is a new prodrug of erythromycin. Its bioavailability from hard gelatin capsules containing the drug with or without sodium bicarbonate was studied in healthy volunteers. The plasma levels of erythromycin, anhydroerythromycin,
Publikováno v:
European journal of drug metabolism and pharmacokinetics.
In our previous study the reasons for fast absorption of ibuprofen from sodium bicarbonate based hard gelatin capsules stayed unclear. These were not investigated using pH regulators (aluminium hydroxide, calcium carbonate, tartaric acid) with differ
Publikováno v:
European Journal of Clinical Pharmacology. 31:367-369
The relative bioavailability and pharmacokinetics of two orally administered aqueous suspensions of noscapine hydrogen embonate were compared with those of noscapine hydrochloride solution. Noscapine hydrochloride showed faster absorption and gave a
Publikováno v:
Arzneimittel-Forschung. 30(10)
The aim of the present study was to extend our earlier research into the effect of osmotic pressure on the intestinal absorption of drugs. In the experiments rats and an in situ technique were used. Sulfafurazol and ethanol were test substances and o
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 20(3)
The bioavailability and effect on the systolic and diastolic blood pressure, heart rate, salivary flow, skin temperature, and subjective sedation of three brands of clonidine were studied in nine healthy volunteers after a single 300-micrograms oral
Publikováno v:
Acta pharmaceutica Nordica. 1(6)
The release of drugs from hard gelatin capsules is often limited by the disintegration rate of the capsule. We set out to determine whether it is possible to hasten the in vivo disintegration of hard gelatin capsules by adding disintegrants (sodium b